DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4991 and skat-1

DIOPT Version :9

Sequence 1:	NP_001259638.1	Gene:	CG4991 / 32695	FlyBaseID:	FBgn0030817	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_498989.1	Gene:	skat-1 / 176271	WormBaseID:	WBGene00010307	Length:	460	Species:	Caenorhabditis elegans

Alignment Length:	485	Identity:	121/485 - (24%)
Similarity:	212/485 - (43%)	Gaps:	72/485 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 SLEKNPERFTKNVTEKGADPENGD------PVRRRGHETSELEAATHLFKGSVGAGLFAMGDCFK 110
            |.|:..||   .||.:|......|      |..|.|...:...|...|.|....||.|::...:|
Worm     2 SEEEGRER---AVTVEGDAESMNDGRALVQPPARSGDVITPTRAVLTLSKSMFNAGCFSLPYAWK 63

  Fly   111 NGGLAGATILLPIIAVMCVHCERMLIRGSVLAVERTPGVDFLDYPETVEKCFEHGP-RPLRKMSR 174
            .|||..:.::..:||.:..:...:|:|.|....:::.. ..|||....:|..::.. |.||..|:
Worm    64 LGGLWVSFVMSFVIAGLNWYGNHILVRASQHLAKKSDR-SALDYGHFAKKVCDYSDIRFLRNNSK 127

  Fly   175 VMKLIVEMFLCVTQFGFCAIYFVFITENL------------HQVLQQNGIVISMSMVMLITLLPA 227
            .:...|.:.:...|.|.|::..:||::||            ||         .|.::..::|...
Worm   128 AVMYFVNVTILFYQLGMCSVAILFISDNLVNLVGDHLGGTRHQ---------QMILMATVSLFFI 183

  Fly   228 MIPSLMTNLKYISPVSLFANVALLFGLIATLTIAFSDGPMPSVGDR----HLFTGGAQLALFFGT 288
            ::.::.|.::.   ||.||.|:.:|.:|....|.......|:..|:    ..|||...:   .|.
Worm   184 LLTNMFTEMRI---VSFFALVSSVFFVIGAAVIMQYTVQQPNQWDKLPAATNFTGTITM---IGM 242

  Fly   289 ALFSYEGIALILPLRNSMRRPEKFSTRFGVLNSTMFFTTALFIFTGFVSYVRWGEEVAGSITLNL 353
            :::::||..:|||:.|.:..|..|...||||::||...||.....||..|..:|:.:|.:||.|:
Worm   243 SMYAFEGQTMILPIENKLDNPAAFLAPFGVLSTTMIICTAFMTALGFFGYTGFGDSIAPTITTNV 307

  Fly   354 VVEEVFSQVVKVIAALGVFLGYPIQFFVMIKILWPPLKRSNNCTQKYPIT----SQVCLRFFMVM 414
            ..|.::| .|.|...|...||..|..:|:..:.:...:|....  ::|..    |....|.|.|:
Worm   308 PKEGLYS-TVNVFLMLQSLLGNSIAMYVVYDMFFNGFRRKFGA--RFPNVPKWLSDKGFRVFWVL 369

  Fly   415 MTFGVALVVPKLNLFISLIGALCSTCLAFVIPVLIDFVTRAQVPKALGVWSYIK----------- 468
            :|:.:|:::|||.:.|.|:|.......|.:.|...:.:|         .|:..|
Worm   370 VTYLMAVLIPKLEIMIPLVGVTSGALCALIFPPFFEMIT---------FWTDWKGLLTYRQRMTK 425

  Fly   469 ---NILILTVAVLGIVTGTYQSIVEIVKEF 495
               |::::.:.|..|:.|.|.:|..|::.|
Worm   426 IFINLVVMAIGVFAIIAGVYTNIHAIIQSF 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4991	NP_001259638.1	SLC5-6-like_sbd	82..489	CDD:294310	107/441 (24%)
CG4991	NP_001259638.1	SdaC	84..488	CDD:223884	107/438 (24%)
skat-1	NP_498989.1	Aa_trans	35..446	CDD:279788	106/438 (24%)
skat-1	NP_498989.1	SdaC	40..448	CDD:223884	107/435 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.030