DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4991 and Slc38a1

DIOPT Version :9

Sequence 1:	NP_001259638.1	Gene:	CG4991 / 32695	FlyBaseID:	FBgn0030817	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_620187.1	Gene:	Slc38a1 / 170567	RGDID:	69645	Length:	485	Species:	Rattus norvegicus

Alignment Length:	467	Identity:	81/467 - (17%)
Similarity:	171/467 - (36%)	Gaps:	104/467 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 LEITGRQN-----DKSLEKNPERFTKNVTEKGADPENG--------DPVRRRGHETSELE----- 88
            ||:|..||     |.::..:...||        :.|||        |...||....|.||
  Rat     8 LELTELQNMTVPEDDNVSNDSNDFT--------EVENGQINSKFISDRESRRSLTNSHLEKRKCD 64

  Fly    89 -----------AATHLFKGSVGAGLFAMGDCFKNGGLAGATILLPIIAVMCVHCERMLIRGSVLA 142
                       :..:|....:|:|:..:.....|.|:....|||..:.::.::...:|     |.
  Rat    65 EYIPGTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLILLTSVTLLSIYSINLL-----LI 124

  Fly   143 VERTPGVDFLDYPETVEKCFEHGPRPLRKMSRVMKLIVEMFLCVTQFGFCAIYFVFITENLHQVL 207
            ..:..|.  :.|.:..|:.|          ....||::.....:...|....|...:...|...:
  Rat   125 CSKETGC--MVYEKLGEQVF----------GTTGKLVIFGATSLQNTGAMLSYLFIVKNELPSAI 177

  Fly   208 QQ-------------NGIVISMSMVMLIT---LLPAMIPSLMTNLKYISPVSLFANVALLFGLIA 256
            :.             :|.|    :|:::|   :||.   .|:.||.|:...|.|:...::|.||.
  Rat   178 KSLMGEEETFSAWYVDGRV----LVVMVTFGIILPL---CLLKNLGYLGYTSGFSLSCMVFFLIV 235

  Fly   257 TLTIAFSDGPMPSVGDRHLFTGGAQL--------ALFFGTALFSYEGIAL-------ILPLRNSM 306
            .:...|.   :|.:......|..|.:        ..|....:::...||.       :||:.:.:
  Rat   236 VIYKKFQ---IPCMNGEQNSTVSANVTDACTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSEL 297

  Fly   307 RRPEKFSTRFGVLNSTMFFTT-ALFIFTGFVSYVRWGEEVAGSITLNL-VVEEVFSQVVKVIAAL 369
            :  ::...:..::::..||.. .::..|....|:.:.|:|...:.... ...::....|::...:
  Rat   298 K--DRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYEKVQSDLLHKYQSTGDILILTVRLAVIV 360

  Fly   370 GVFLGYPIQFFVMIKILWPPLKRSNNCTQKYPITSQVCLRFFMVMMTFGVALVVPKLNLFISLIG 434
            .|.|..|:.||.:...|:...|::     |:.:...|.:...::::...:.:.:|.:.....::|
  Rat   361 AVILTVPVLFFTVRSSLFELAKKT-----KFHLCRHVLVTIILLVIINLLVIFIPSMKDIFGVVG 420

  Fly   435 ALCSTCLAFVIP 446
            ...:..|.|::|
  Rat   421 VTSANMLIFILP 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4991	NP_001259638.1	SLC5-6-like_sbd	82..489	CDD:294310	67/414 (16%)
CG4991	NP_001259638.1	SdaC	84..488	CDD:223884	67/412 (16%)
Slc38a1	NP_620187.1	SLC5-6-like_sbd	69..472	CDD:382020	64/398 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352582
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D697331at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.860