DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4991 and Slc36a1

DIOPT Version :9

Sequence 1:	NP_001259638.1	Gene:	CG4991 / 32695	FlyBaseID:	FBgn0030817	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_569099.1	Gene:	Slc36a1 / 155205	RGDID:	619801	Length:	475	Species:	Rattus norvegicus

Alignment Length:	464	Identity:	146/464 - (31%)
Similarity:	247/464 - (53%)	Gaps:	41/464 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 DKSLEKNPERFTKNVTEKGADPENGDPVRRRGHETSE--LEAATHLFKGSVGAGLFAMGDCFKNG 112
            |.|.|::|        .:|....:....:|.|..:|.  .:...||.||::|.||..:....||.
  Rat    18 DVSPEESP--------SEGLGSFSPGSYQRLGENSSMTWFQTLIHLLKGNIGTGLLGLPLAVKNA 74

  Fly   113 GLAGATILLPIIAVMCVHCERMLIRGSVLAVERTPGVDFLDYPETVEKCFEHGPRP-LRKMSRVM 176
            ||....:.|.:|.::.|||..:|::.:.....|. ...||||.:||....|..|.. :|..|...
  Rat    75 GLLLGPLSLLVIGIVAVHCMGILVKCAHHLCRRL-NKPFLDYGDTVMYGLECSPSTWIRNHSHWG 138

  Fly   177 KLIVEMFLCVTQFGFCAIYFVFITENLHQVLQ-QNG----------IVISMSM---VMLITLLPA 227
            :.||:.||.|||.|||.:||||:.:|..||:: .||          ::::.:|   :.::|.||.
  Rat   139 RRIVDFFLVVTQLGFCCVYFVFLADNFKQVIEAANGTTTNCNNNETVILTPTMDSRLYMLTFLPF 203

  Fly   228 MI-PSLMTNLKYISPVSLFANVALLFGLIATLTIAFSDGPMPSVGDRH--LFTGGAQLALFFGTA 289
            :: .|.:.||:.:|..||.||:::...||..........|.||    |  |........||||||
  Rat   204 LVLLSFIRNLRILSIFSLLANISMFVSLIMIYQFIVQRIPDPS----HLPLVAPWKTYPLFFGTA 264

  Fly   290 LFSYEGIALILPLRNSMRRPEKFSTRFGVLNSTMFFTTALFIFTGFVSYVRWGEEVAGSITLNLV 354
            :|::|||.::|||.|.|:..:||..   :|...|...|.|:|..|.:.|:::|.::.|||||||.
  Rat   265 IFAFEGIGVVLPLENKMKDSQKFPL---ILYLGMAIITVLYISLGSLGYLQFGADIKGSITLNLP 326

  Fly   355 VEEVFSQVVKVIAALGVFLGYPIQFFVMIKILWPPLKRSNNCTQKYPITSQVCLRFFMVMMTFGV 419
            ...:: |.||::.::|:|..|.:||:|..:|:.|.:  .:...:::.:...:..|..||.:|..:
  Rat   327 NCWLY-QSVKLLYSIGIFFTYALQFYVAAEIIIPAI--VSRVPERFELVVDLSARTAMVCVTCVL 388

  Fly   420 ALVVPKLNLFISLIGALCSTCLAFVIPVLIDFVTRAQVPKALGVWSYIKNILILTVAVLGIVTGT 484
            |:::|:|:|.|||:|::.|:.||.:||.|::..|  ...:.:...:..|:.||..:..:|.|.||
  Rat   389 AVLIPRLDLVISLVGSVSSSALALIIPPLLEVTT--YYGEGISPLTITKDALISILGFVGFVVGT 451

  Fly   485 YQSIVEIVK 493
            |:|:.|:::
  Rat   452 YESLWELIQ 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4991	NP_001259638.1	SLC5-6-like_sbd	82..489	CDD:294310	138/426 (32%)
CG4991	NP_001259638.1	SdaC	84..488	CDD:223884	137/423 (32%)
Slc36a1	NP_569099.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32		5/21 (24%)
Slc36a1	NP_569099.1	SLC5-6-like_sbd	47..452	CDD:382020	134/417 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352563
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.960