Protein Alignment CG4991 and SLC38A8

DIOPT Version :9

• Sequence 1: NP_001259638.1
• Gene: CG4991 / 32695
• FlyBaseID: FBgn0030817
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001073911.1
• Gene: SLC38A8 / 146167
• HGNCID: 32434
• Length: 435
• Species: Homo sapiens
• Alignment Length: 480
• Identity: 96/480 - (20%)
• Similarity: 172/480 - (35%)
• Gaps: 114/480 - (23%)

  Fly    71 PENGDPVRRRGHETSELEAATHLFKGSVGAGLFAMGDCFKNGGLAGATILLPIIAVMCVHCERML 135
            ||...|..... ..|.:.|...|.|.::||||......|...|......|:.:::::      .|
Human    12 PEKPHPATAAA-TLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLV------FL 69

  Fly   136 IRGSVLAVERTPGVDFLDYPETVE-----------KCFEHGPRPLRKMSRVMKLIVEMFLCVTQF 189
            |.|.|:          |.|...|.           .|   || .:.|:.....|:..:.:.|.
Human    70 ISGLVI----------LGYAAAVSGQATYQGVVRGLC---GP-AIGKLCEACFLLNLLMISVA-- 118

  Fly   190 GFCAIYFVFITENLHQVLQQ--NGIV-----------ISMSMVMLITLLPAMIPSLMTNLKYISP 241
                 :...|.:.|.::...  :|..           .::.::.::.:||...|..:...||
Human   119 -----FLRVIGDQLEKLCDSLLSGTPPAPQPWYADQRFTLPLLSVLVILPLSAPREIAFQKY--- 175

  Fly   242 VSLFANVALLFGLIATLTIAFSDGPMPSVGDRH-LFTGGAQLALF--FGTALFSYEGIALILPLR 303
            .|:...:|..: |...:|:.:...|...|.:.| ..:..:..::|  |.|..|.::.....:.:.
Human   176 TSILGTLAACY-LALVITVQYYLWPQGLVRESHPSLSPASWTSVFSVFPTICFGFQCHEAAVSIY 239

  Fly   304 NSMRRPEKFSTRFGVLNSTMFFTTALFIF--TGFVSYVRWGEEVAGSITLNLVVEEVFSQVVKVI 366
            .|||   |.|.....|.|.:.......|:  ||...::.:|.||:..:.::....::...|.:|:
Human   240 CSMR---KRSLSHWALVSVLSLLACCLIYSLTGVYGFLTFGTEVSADVLMSYPGNDMVIIVARVL 301

  Fly   367 AALGVFLGYPIQFFVMIKIL-----------WPP--LKRSNNCTQKYPITSQVCLRFFMVMMTFG 418
            .|:.:...|||..|:...::           |.|  |...:....:.|:|      ...|.:|..
Human   302 FAVSIVTVYPIVLFLGRSVMQDFWRRSCLGGWGPSALADPSGLWVRMPLT------ILWVTVTLA 360

  Fly   419 VALVVPKLNLFISLIG-----------ALCSTCLAFVIPVLIDFVTRAQVPKALGVWSYIKNILI 472
            :||.:|.|:..:|:||           .||..|...|.|:      ..:|...|.||
Human   361 MALFMPDLSEIVSIIGGISSFFIFIFPGLCLICAMGVEPI------GPRVKCCLEVW-------- 411

  Fly   473 LTVAVLGIVTGTY---QSIVEIVKE 494
               .|:.::.||:   ||....|.|
Human   412 ---GVVSVLVGTFIFGQSTAAAVWE 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4991	NP_001259638.1	SLC5-6-like_sbd	82..489	CDD:294310	91/462 (20%)
		SdaC	84..488	CDD:223884	90/459 (20%)
SLC38A8	NP_001073911.1	SdaC	23..431	CDD:223884	91/464 (20%)
		SLC5-6-like_sbd	23..431	CDD:294310	91/464 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158541
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D697331at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.860