Protein Alignment CG4991 and SLC38A6

DIOPT Version :9

• Sequence 1: NP_001259638.1
• Gene: CG4991 / 32695
• FlyBaseID: FBgn0030817
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001166173.1
• Gene: SLC38A6 / 145389
• HGNCID: 19863
• Length: 521
• Species: Homo sapiens
• Alignment Length: 479
• Identity: 89/479 - (18%)
• Similarity: 172/479 - (35%)
• Gaps: 122/479 - (25%)

  Fly    69 ADPENGDPV------RRRGHETSELEAATHLFKGSVGAGLFAMGDCFKNGGLAGATILLPIIAVM 127
            |:.|...|:      |:|....|...:..:|....:|:|:..:.....|.|:.|.:.||..:|::
Human    24 AEAEELSPLLSNELHRQRSPGVSFGLSVFNLMNAIMGSGILGLAYVLANTGVFGFSFLLLTVALL 88

  Fly   128 CVHCERML----IRGSVLAVE-------RTPGVDFLDYPETVEKCFEHGPRPLRKMSRVMKLIVE 181
            ..:...:|    |:.:|.:.|       ..||                            ||:|.
Human    89 ASYSVHLLLSMCIQTAVTSYEDLGLFAFGLPG----------------------------KLVVA 125

  Fly   182 MFLCVTQFGFCAIYFVFITENLHQVLQQ------------NG----IVISMSMVMLITLLPAMIP 230
            ..:.:...|..:.|.:.|...|...:.:            :|    |:|.:.:|..:.|||.
Human   126 GTIIIQNIGAMSSYLLIIKTELPAAIAEFLTGDYSRYWYLDGQTLLIIICVGIVFPLALLPK--- 187

  Fly   231 SLMTNLKYISPVSLFANVALLFGLIA-----------TLTIAFSDGPMPSVGD---RHLFTGGAQ 281
              :..|.|.|.:|.|  ..:.|.|:.           ||........:.:|.|   ..||....:
Human   188 --IGFLGYTSSLSFF--FMMFFALVVIIKKWSIPCPLTLNYVEKGFQISNVTDDCKPKLFHFSKE 248

  Fly   282 LALFFGTALFSYEGIALILPLRNSMRRPEKFSTRFGVLNSTMFFTTALFIFTGFVSYVRWGEEVA 346
            .|....|..||:.....|||:...::.|.|...: .|.|:.:..:..::..:....|:.:.::|.
Human   249 SAYALPTMAFSFLCHTSILPIYCELQSPSKKRMQ-NVTNTAIALSFLIYFISALFGYLTFYDKVE 312

  Fly   347 GSIT---LNLVVEEVFSQVVKVIAALGVFLGYPIQFFVMIKILWPPLKRSNNCT--QKYPITSQV 406
            ..:.   ...:..:|....||:.....|.|..|:..|        |.:::....  ..:|.:
Human   313 SELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHF--------PARKAVTMMFFSNFPFS--- 366

  Fly   407 CLRFFMVMMTFGV-----ALVVPKLNLFISLIGALCSTCLAFVIPVLI-------DFVTRAQVPK 459
            .:|.|::.:...:     |:.||.:.....::||..||||.|:.|.|.       ||::
Human   367 WIRHFLITLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLKLSREDFLS------ 425

  Fly   460 ALGVWSYIKNILIL-TVAVLGIVT 482
                |..:..:::. .:|..|:::
Human   426 ----WKKLGGLILSHRLACSGVIS 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4991	NP_001259638.1	SLC5-6-like_sbd	82..489	CDD:294310	84/460 (18%)
		SdaC	84..488	CDD:223884	84/458 (18%)
SLC38A6	NP_001166173.1	SLC5-6-like_sbd	46..429	CDD:294310	82/439 (19%)
		SdaC	50..434	CDD:223884	81/440 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158550
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D697331at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.860