DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4991 and slc36a1

DIOPT Version :9

Sequence 1:	NP_001259638.1	Gene:	CG4991 / 32695	FlyBaseID:	FBgn0030817	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	XP_017948307.1	Gene:	slc36a1 / 100492769	XenbaseID:	XB-GENE-976345	Length:	480	Species:	Xenopus tropicalis

Alignment Length:	465	Identity:	145/465 - (31%)
Similarity:	247/465 - (53%)	Gaps:	30/465 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 RQND-KSLEKNP--ERFTKNVTEKGADPENGDPVRRRGHETSELEAATHLFKGSVGAGLFAMGDC 108
            |.|| .|.|.:|  |.....::...:.|.....:......|:..:...||.||::|.||.::...
Frog    10 RYNDYSSTEASPSEESPPGTISNYVSGPRRYQRLGEDSSSTTWYQTLIHLLKGNIGTGLLSLPLA 74

  Fly   109 FKNGGLAGATILLPIIAVMCVHCERMLIRGSVLAVERTPGVDFLDYPETVEKCFEHGPRP-LRKM 172
            .||.|:....:.|..:.::.|||..:|::.:....:|... .|:||.:.:....:..|.. |::.
Frog    75 VKNAGIVLGPLSLVFMGIIAVHCMDLLVKCAHHLCQRNQR-PFVDYGDALMYSMQGSPSQWLQRH 138

  Fly   173 SRVMKLIVEMFLCVTQFGFCAIYFVFITENLHQVLQ-QNG------------IVISM-SMVMLIT 223
            |...:.||..||.:||.|||.:||||:.:|:.||:: .||            :|.|| |.:.:::
Frog   139 SVWGRRIVGFFLILTQLGFCCVYFVFLADNIKQVVEAANGTTNDCSSNETLVLVESMDSRLYILS 203

  Fly   224 LLPAMIPSL-MTNLKYISPVSLFANVALLFGLIATLTIAFSDGPMPSVGDRHLFTGGAQLALFFG 287
            .||.:|..: :|||:|:|..||.||:::|..:|........|.|.|:  .....:.....|||||
Frog   204 FLPFLILLVFITNLRYLSIFSLLANLSMLGSVIMIYQYIGRDIPDPT--SLSFVSSWRSYALFFG 266

  Fly   288 TALFSYEGIALILPLRNSMRRPEKFSTRFGVLNSTMFFTTALFIFTGFVSYVRWGEEVAGSITLN 352
            ||:|::|||.::|||.|.|:.|.:|..   ||...|...|.|:|..|.:.|:|:|..:..|||||
Frog   267 TAIFAFEGIGVVLPLENKMKIPHQFPV---VLYVGMGIVTILYISMGTLGYLRFGSSIQASITLN 328

  Fly   353 LVVEEVFSQVVKVIAALGVFLGYPIQFFVMIKILWPPLKRSNNCTQKYPITSQVCLRFFMVMMTF 417
            | ....|.|.||::.:.|:|:.:.:||:|..:|:.|.:  :.:...::.....:.:|..:|.:|.
Frog   329 L-PNCWFYQSVKLLYSFGIFITFALQFYVAAEIIVPAV--TLHVHDRWVRCMDLTVRAALVCITC 390

  Fly   418 GVALVVPKLNLFISLIGALCSTCLAFVIPVLIDFVTRAQVPKALGVWSYIKNILILTVAVLGIVT 482
            .:|:::|.|.|.|||:|::.|:.||.:||.|::.:|  ...:.|..|...|:|.|..:.:||.|.
Frog   391 VLAILIPHLGLVISLVGSVSSSALALIIPPLLEILT--YYTEGLSRWVISKDIFISLLGILGFVL 453

  Fly   483 GTYQSIVEIV 492
            |||.::.|::
Frog   454 GTYVALWELI 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4991	NP_001259638.1	SLC5-6-like_sbd	82..489	CDD:294310	136/422 (32%)
CG4991	NP_001259638.1	SdaC	84..488	CDD:223884	136/419 (32%)
slc36a1	XP_017948307.1	SLC5-6-like_sbd	50..459	CDD:382020	136/419 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.030