Protein Alignment CG16700 and SLC38A5

DIOPT Version :10

• Sequence 1: NP_573191.1
• Gene: CG16700 / 32694
• FlyBaseID: FBgn0030816
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: XP_054184094.1
• Gene: SLC38A5 / 92745
• HGNCID: 18070
• Length: 541
• Species: Homo sapiens
• Alignment Length: 518
• Identity: 109/518 - (21%)
• Similarity: 202/518 - (38%)
• Gaps: 107/518 - (20%)

  Fly    16 TVPRQET-------AEGGSTGETAVG------------GAA--AKVTKEQDHDAEYHPPTSYLET 59
            |.|.|||       ...|:....|||            |.|  :|..:..|.:.:    ||:..:
Human    40 TPPPQETRMELQDPKMNGALPSDAVGYRQEREGFLPSRGPAPGSKPVQFMDFEGK----TSFGMS 100

  Fly    60 IVHLFKGNIGPGLFAMGDAFKNGGLLVAPLLTVVIAVVSIHCQHVLVTCSKKMRDLKGDSVCADY 124
            :.:|....:|.|:..:..|..:.|::....|.:.||::|.:..|:|:||:       |.:....|
Human   101 VFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCA-------GIAGIRAY 158

  Fly   125 AQTVEQCFENGPSKLRGWSRTMGR-LVDIFICVTQLGFCCIYFVFISTNLKQILQAY-------D 181
            .|..::.|  ||:         |: :|...||:..:|....|...|.:.|..::..:       |
Human   159 EQLGQRAF--GPA---------GKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPEGD 212

  Fly   182 IDMNVHLVMLLAFVPVLLS-SLITNLKWLTPVSMFANVCMILGLAITLYYALK------------ 233
            ..:..:|::::..|.::|. :|:.:|.:|...|..:..||:..|...:|...:
Human   213 WFLKGNLLIIIVSVLIILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAIGHNETAM 277

  Fly   234 ----------DGLPEVEERALWTNGSQLALFFGTAIFAFEGIALVMPLKNAMRKPHQFERPLGVL 288
                      .||....|..::|..||::.......|||.....|:|:...:.:|.: .|...|.
Human   278 ESEALVGLPSQGLNSSCEAQMFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPSK-RRMQAVA 341

  Fly   289 NVGMFLVSVMFMFAGSVGYMKWGEQVGGSL--TLNLGDTILAQAVKLMVSAGVLLGYPLQFFV-- 349
            ||.:..:..|:....:.||:.:...|...:  ..:..|.::. .|:|.|...|.|..|:..|.
Human   342 NVSIGAMFCMYGLTATFGYLTFYSSVKAEMLHMYSQKDPLIL-CVRLAVLLAVTLTVPVVLFPIR 405

  Fly   350 -AIQ--------IMWPNAKQMCGIEGRSLLGELGFRTFMVLVTLAIAEMVPALGLFISLIGALCS 405
             |:|        ..||....:..|             .:|||.:.:. .||.:.....:||:..:
Human   406 RALQQLLFPGKAFSWPRHVAIALI-------------LLVLVNVLVI-CVPTIRDIFGVIGSTSA 456

  Fly   406 TALALVFPPVIEL-ISRSELNKGPGI-WICVKNLVILVLALLGFFTGSYESLKQIVKHFGEEE 466
            .:|..:.|.:..| |..||:.  |.: |..::.....::||:...|...|..::..:...|||
Human   457 PSLIFILPSIFYLRIVPSEVE--PFLSWPKIQGCQAWIMALIPTPTPWEEEEEEEEEEEEEEE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16700	NP_573191.1	SLC5-6-like_sbd	53..452	CDD:444915	92/444 (21%)
SLC38A5	XP_054184094.1	SLC5-6-like_sbd	93..484	CDD:444915	89/430 (21%)