DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG16700 and LAX2

DIOPT Version :9

Sequence 1:	NP_573191.1	Gene:	CG16700 / 32694	FlyBaseID:	FBgn0030816	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_179701.1	Gene:	LAX2 / 816640	AraportID:	AT2G21050	Length:	483	Species:	Arabidopsis thaliana

Alignment Length:	495	Identity:	94/495 - (18%)
Similarity:	182/495 - (36%)	Gaps:	93/495 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LEKNQTATVPRQETAEGGSTGETAVGGAAAKVTKEQDHDAEYHPPTSYLETIVHLFKGNIGPGLF 73
            :|..:.|.    ||...|:..|....|.|..: |.:..|..:|..::| :.........:...|.
plant     1 MENGEKAA----ETVVVGNYVEMEKDGKALDI-KSKLSDMFWHGGSAY-DAWFSCASNQVAQVLL 59

  Fly    74 AMGDAFKNGGLLVAPLLTVVIAVVSIHCQHVLVTCSKKMRDLKGDSVCADYAQTVEQCFENGPSK 138
            .:..:|...|:|...|..:...::.....:::.....:.|..| :....::...|.|.||.....
plant    60 TLPYSFSQLGMLSGILFQLFYGILGSWTAYLISILYVEYRTRK-EREKVNFRNHVIQWFEVLDGL 123

  Fly   139 LRGWSRTMGRLVD----IFICVTQLGFCCIYFVFISTNLKQILQAYDIDMNVHLVMLLAFVPVLL 199
            |....|.:|...:    :|..|.||..|.....:|:.||.:....|....   ......|:|
plant   124 LGKHWRNVGLAFNCTFLLFGSVIQLIACASNIYYINDNLDKRTWTYIFGA---CCATTVFIP--- 182

  Fly   200 SSLITNLKWLTPVSMFAN--VCMILGLAITLYYA----LKDGLPEVEERALWTNGSQLALFFGTA 258
                          .|.|  :...|||.:|.|.|    :...|....|....:..|:|.|:|..|
plant   183 --------------SFHNYRIWSFLGLLMTTYTAWYLTIASILHGQVEGVKHSGPSKLVLYFTGA 233

  Fly   259 ---IFAFEGIALVMPLKNAMRKPHQFERPLGVLNVGMFLVSVMFMF-----AGSVGYMKWGEQVG 315
               ::.|.|.|:.:.:.:||.||.:|:        .::|.:.:::.     :.|..|..:|:
plant   234 TNILYTFGGHAVTVEIMHAMWKPQKFK--------SIYLFATLYVLTLTLPSASAVYWAFGD--- 287

  Fly   316 GSLTLNLGDTILA---------QAVKLMVSAGVLLGY---PLQFFVAIQIMWPNAKQMCGI-EGR 367
              |.||..:....         ..|.:::...:..|:   ||.|      :|   :::.|: |.|
plant   288 --LLLNHSNAFALLPKNLYRDFAVVLMLIHQFITFGFACTPLYF------VW---EKLIGMHECR 341

  Fly   368 SLLGELGFRTFMVLVTLAIAEMVPALGLFISLIGALCSTALALVFPPVIELIS-------RSELN 425
            |:......|..:|:....:|.:.|..|...|.:|:|..:....:.|.:..:.:       .:.:.
plant   342 SMCKRAAARLPVVIPIWFLAIIFPFFGPINSTVGSLLVSFTVYIIPALAHIFTFRSSAARENAVE 406

  Fly   426 KGP---GIW---ICVKNLVILVLALLGFFTGSYESLKQIV 459
            :.|   |.|   ..:...:::.:.::||..|.:.|:...|
plant   407 QPPRFLGRWTGAFTINAFIVVWVFIVGFGFGGWASMINFV 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16700	NP_573191.1	SLC5-6-like_sbd	53..452	CDD:294310	81/442 (18%)
CG16700	NP_573191.1	SdaC	57..452	CDD:223884	80/438 (18%)
LAX2	NP_179701.1	PLN03074	2..461	CDD:215559	94/494 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810