DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16700 and slc38a9

DIOPT Version :9

Sequence 1:	NP_573191.1	Gene:	CG16700 / 32694	FlyBaseID:	FBgn0030816	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_001073468.1	Gene:	slc38a9 / 562137	ZFINID:	ZDB-GENE-061013-597	Length:	549	Species:	Danio rerio

Alignment Length:	499	Identity:	104/499 - (20%)
Similarity:	188/499 - (37%)	Gaps:	127/499 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 GAAAKVTKEQDHDAEYHPPTSYLETIVHLFKGNIGPGLFAMGDAFKNGGLLVAPLLTVVIAVVSI 99
            |.|.||   |..|:....|:  :.||..::...:|..:.::....|..|..:..::.|::.::::
Zfish    91 GTAFKV---QGGDSPIKNPS--IVTIFAIWNTMMGTSILSIPWGIKQAGFTLGIIIIVLMGLLTL 150

  Fly   100 HCQHVLVTCSKKM-----RDLKGDSVCADYAQTVEQCFENGPSKLRGWSRTMGRLVDIFICVTQL 159
            :|.:.::..:|.:     .|.:...||..|.        .|..|   ||..      :|..|:.:
Zfish   151 YCCYRVLKSTKSIPYVDTSDWEFPDVCKYYF--------GGFGK---WSSL------VFSLVSLI 198

  Fly   160 GFCCIYFVFISTNL-------------------------KQILQAY-DIDMN------------- 185
            |...:|:|.:|..|                         ::::..| |:|.:
Zfish   199 GAMVVYWVLMSNFLFNTGKFIFNYVHNVNTSDAFGTNGTERVICPYPDVDPHGNSSTSLYSGSDN 263

  Fly   186 ---------------VHLVMLLAFVPVL---LSSLITNLKWLTPVSMFANVCMILGLAITLYYAL 232
                           :...::|..:|:|   .:|......:|..:|:...:.::...||.|.:.|
Zfish   264 STGLEFDHWWSKTNTIPFYLILLLLPLLNFRSASFFARFTFLGTISVIYLIFLVTYKAIQLGFHL 328

  Fly   233 K----DG----LPEVEERALWTNGSQLALFFGTAIFAFEGIALVMPLKNAMRKPHQFERPLGVLN 289
            :    |.    :||.  |.|:   .||:.....|.|....|..:|  ||   ..|| |..:..|:
Zfish   329 EFHWFDSSMFFVPEF--RTLF---PQLSGVLTLAFFIHNCIITLM--KN---NKHQ-ENNVRDLS 382

  Fly   290 VGMFLVSVMFMFAGSVGYMKWGEQVGGS--LTLNLGDTILAQAVKLMVSAGVLL-----GYP-LQ 346
            :...||.:.:::.|.:.:..:.......  :..|..|...:..:.:.|:...||     .|| |.
Zfish   383 LAYLLVGLTYLYVGVLIFAAFPSPPLSKECIEPNFLDNFPSSDILVFVARTFLLFQMTTVYPLLG 447

  Fly   347 FFVAIQIMWPNAKQMCGIEGRSLLGELGFRTFMVLVTLAIAEMVPALGLFISLIGALCSTALALV 411
            :.|.:|:|    .|:.|......|.......|:|...:.:|...|.:|..|...||||..||..|
Zfish   448 YLVRVQLM----GQIFGNHYPGFLHVFVLNVFVVGAGVLMARFYPNIGSIIRYSGALCGLALVFV 508

  Fly   412 FPPVIELIS---RSELNKGPGIWICV---KNLVILVLA-LLGFF 448
            .|.:|.::|   |.||.     |...   ..|::|.:| |||.|
Zfish   509 LPSLIHMVSLKRRGELR-----WTSTLFHGFLILLGVANLLGQF 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16700	NP_573191.1	SLC5-6-like_sbd	53..452	CDD:294310	98/481 (20%)
CG16700	NP_573191.1	SdaC	57..452	CDD:223884	97/477 (20%)
slc38a9	NP_001073468.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..27
		SdaC	100..549	CDD:223884	99/487 (20%)
		SLC5-6-like_sbd	110..538	CDD:294310	91/464 (20%)
		Important for arginine binding and amino acid transport. /evidence=ECO:0000269\|PubMed:29872228	117..122		1/4 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594542
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.830