Protein Alignment CG16700 and SLC38A4

DIOPT Version :10

• Sequence 1: NP_573191.1
• Gene: CG16700 / 32694
• FlyBaseID: FBgn0030816
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_060488.2
• Gene: SLC38A4 / 55089
• HGNCID: 14679
• Length: 547
• Species: Homo sapiens
• Alignment Length: 558
• Identity: 110/558 - (19%)
• Similarity: 210/558 - (37%)
• Gaps: 168/558 - (30%)

  Fly    18 PRQETAEGGSTGETAVG-GAAAKV----------TKEQ--------------DHDAEYHP-PTSY 56
            |..|::.|.|..::.:| |.:.|.          |:.|              |:..|:|| .||:
Human    13 PDDESSSGESAPDSYIGIGNSEKAAMSSQFANEDTESQKFLTNGFLGKKKLADYADEHHPGTTSF 77

  Fly    57 LETIVHLFKGNIGPGLFAMGDAFKNGGLLVAPLLTVVIAVVSIHCQHVLVTCSKKMRDLKGDSVC 121
            ..:..:|....:|.|:..:..|..|.|:::..::.:.:|::|::..|:|:..:|     :|.|:.
Human    78 GMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLKTAK-----EGGSLI 137

  Fly   122 ADYAQTVEQCFENGPSKLRGWSRTMGRLVDIFICVTQLGFCCIYFVFISTNLKQILQAY-DIDMN 185
              |.:..|:.|        ||...:|..|.  |.:..:|....|...|...|.::::|: .::.|
Human   138 --YEKLGEKAF--------GWPGKIGAFVS--ITMQNIGAMSSYLFIIKYELPEVIRAFMGLEEN 190

  Fly   186 V--------HLVMLLAFVPVLLSSLITNLKWLTPVSMFANVCMILGLAITLY------------- 229
            .        :|::.::...:|..||:.||.:|...|.|:..||:..:::.:|
Human   191 TGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLPVLD 255

  Fly   230 ---------------------------------YALKD--GLPEVEER-ALWTNG---------- 248
                                             |..::  ||.|.:.: :|..:|
Human   256 HSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDENQAKGSLHDSGVEYEAHSDDK 320

  Fly   249 ---------SQLALFFGTAIFAF----EGIALVMPLKNAMRKPHQFERPLGVLNVGMFLVSVMFM 300
                     |:.|......:|||    |.:.:...||:..|:..|     .|.|:.:..:.||::
Human   321 CEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKMQ-----TVSNISITGMLVMYL 380

  Fly   301 FAGSVGYMKWGEQVGGSL--------TLNLGDTILAQAVKLMVSAGVLLGYPLQFF----VAIQI 353
            .|...||:.:..:|...|        ||:    |....|:|.|...|.|..|:..|    ..|.:
Human   381 LAALFGYLTFYGEVEDELLHAYSKVYTLD----IPLLMVRLAVLVAVTLTVPIVLFPIRTSVITL 441

  Fly   354 MWPNAKQMCGIEGRSLLGELGFRTFMVLVTL--AIAEMVPALGLFISLIGALCSTALALVFPPVI 416
            ::|.         |.......|....||:.|  .:..:||.:......|||..:|.|..:.|.|.
Human   442 LFPK---------RPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVF 497

  Fly   417 EL-ISRSELNKGP-----------GIWICVKNLVILVL 442
            .| :.:.|..:.|           ||:..:.::.::::
Human   498 YLKLVKKETFRSPQKVGALIFLVVGIFFMIGSMALIII 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16700	NP_573191.1	SLC5-6-like_sbd	53..452	CDD:444915	97/497 (20%)
SLC38A4	NP_060488.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30		4/16 (25%)
		SLC5-6-like_sbd	73..535	CDD:444915	97/496 (20%)