DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16700 and slc36a4

DIOPT Version :9

Sequence 1:	NP_573191.1	Gene:	CG16700 / 32694	FlyBaseID:	FBgn0030816	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	XP_002664741.3	Gene:	slc36a4 / 504109	ZFINID:	ZDB-GENE-050309-239	Length:	488	Species:	Danio rerio

Alignment Length:	473	Identity:	166/473 - (35%)
Similarity:	269/473 - (56%)	Gaps:	53/473 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 PRQETAEGGSTGETA-VGGAAAKVTKEQDHDAEYHPP-TSYLETIVHLFKGNIGPGLFAMGDAFK 80
            |..|.|||....|.. |.|         |.|:::.|. .::.:|::||.|||||.||..:..|.|
Zfish    14 PLMEKAEGEEEEEDENVDG---------DEDSKHLPQGITFTQTLLHLLKGNIGTGLLGLPLAVK 69

  Fly    81 NGGLLVAPLLTVVIAVVSIHCQHVLVTCSKKMRD-LKGDSVCADYAQTVEQCFENGPSKLRGWSR 144
            |.|:::.|:..|::.||.:||.|:||.||.::.: ||...:  .|::||....|...|:....|.
Zfish    70 NAGIVLGPVSLVLMGVVCVHCMHILVNCSHQLSERLKRSPL--GYSETVAAAMELSSSQCLRRSA 132

  Fly   145 TMGR-LVDIFICVTQLGFCCIYFVFISTNLKQILQ------------------------AYDIDM 184
            ..|| ||:.|:.:||||||.:||||::.|:||:::                        :..||:
Zfish   133 HFGRHLVNFFLVLTQLGFCSVYFVFLAENIKQVMEGTHMNSTAETVLLSSNSSEASVASSVAIDL 197

  Fly   185 NVHLVMLLAFVPVLLSSLITNLKWLTPVSMFANVCMILGLAITLYYALKDGLPEVEERALWTNGS 249
            .:::|.||.|:.||  :.|.:|:.:..:|..||:||.:.|.....|.|.| |.:.......:...
Zfish   198 RLYMVFLLPFIIVL--TFIRDLRNMAALSAIANLCMAISLIFIFSYILND-LSDPRRLPYASTWR 259

  Fly   250 QLALFFGTAIFAFEGIALVMPLKNAMRKPHQFERPLGVLNVGMFLVSVMFMFAGSVGYMKWGEQV 314
            :...||||||||||||.:|:||:|.||:|.:|.:   .||:||..:.|:::...::||:::.:.:
Zfish   260 KFPFFFGTAIFAFEGIGVVLPLENQMREPKRFPQ---ALNIGMGFIIVLYVTLATLGYLRFRDDI 321

  Fly   315 GGSLTLNL-GDTILAQAVKLMVSAGVLLGYPLQFFVAIQIMWPNAKQMCGIEGRS--LLGELGFR 376
            .||:|||| .|:...|.||::.|.||.:.:.:||||..:|:.|   .||....:|  .:.:|..|
Zfish   322 KGSITLNLPHDSWSNQLVKVLYSFGVFVSFAVQFFVPAEILLP---PMCERVRKSWRRVADLSLR 383

  Fly   377 TFMVLVTLAIAEMVPALGLFISLIGALCSTALALVFPPVIELISRSELNKGPGIWICVKNLVILV 441
            ..:|.:|...|.::|.|.|.|||:||:.|:||||||||::|||:..  ::.|...:.:|::.|..
Zfish   384 ALLVCLTCVTAVLIPRLDLVISLVGAVSSSALALVFPPLVELIAFP--SQPPPPMLLLKDISIAA 446

  Fly   442 LALLGFFTGSYESLKQIV 459
            |..:||.||:|.::::|:
Zfish   447 LGFIGFLTGTYVTVEEII 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16700	NP_573191.1	SLC5-6-like_sbd	53..452	CDD:294310	153/428 (36%)
CG16700	NP_573191.1	SdaC	57..452	CDD:223884	153/423 (36%)
slc36a4	XP_002664741.3	SLC5-6-like_sbd	42..460	CDD:294310	154/430 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594530
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm6436
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R126
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.990