DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16700 and slc38a6

DIOPT Version :9

Sequence 1:	NP_573191.1	Gene:	CG16700 / 32694	FlyBaseID:	FBgn0030816	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_001008117.2	Gene:	slc38a6 / 493479	XenbaseID:	XB-GENE-1016511	Length:	448	Species:	Xenopus tropicalis

Alignment Length:	447	Identity:	92/447 - (20%)
Similarity:	169/447 - (37%)	Gaps:	94/447 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 TSYLETIVHLFKGNIGPGLFAMGDAFKNGGLLVAPLLTVVIAVVSIHCQHV-----LVTCSKKMR 113
            ||:...:.:|....:|.|:..:..|....|:|....|.:::|:::.:..|:     |:|......
Frog    39 TSFGFAVFNLMNAIMGSGILGLSYAMAKTGILGFSALLLIVALLAAYSIHLLLRMCLLTAVTSYE 103

  Fly   114 DLKGDSVCADYAQTVEQCFENGPSKLRGWSRTMGRLVDIFICVTQLGFCCIYFVFISTNLKQILQ 178
            ||                      .|..:.|:...||...|.:..:|....|...|.:.|...:.
Frog   104 DL----------------------GLYAFGRSGKVLVACTILIQNVGAMSSYLFIIKSELPAAIA 146

  Fly   179 AY-----------D-----IDMNVHLVMLLAFVP----------------VLLSSLITNLKWLTP 211
            ::           |     |..:|.:|:.||.:|                |..:.:|...||..|
Frog   147 SFLPGAQGEPWYLDGRTLLIITSVCIVLPLALLPKIGFLGYTSSLSFFFMVYFAVVIVIKKWNIP 211

  Fly   212 VSMFANVCMILGLAITLYYALKDGLPEVEERALWTNGSQLALFFGTAIFAFEGIALVMPLKNAMR 276
                   |.:..|..|:.:.....:.|.:.: |:....:.|....|..|:|.....|:|:...::
Frog   212 -------CPLPPLNHTVTFLQAPNISECKPK-LFDFSKESAFALPTMAFSFLCHTSVLPIYCELK 268

  Fly   277 KPHQFERPLGVLNVGMFLVSVMFMFAGSVGYMKWGEQVGGSL----TLNLGDTILAQAVKLMVSA 337
            .|.: .:...|.|||:.|..:::..:...||:.:.:.|...|    :..|...:|...|:|.:..
Frog   269 SPSK-SKMQNVANVGIALSFLIYYISALFGYLTFYDNVKSELLQGYSKYLPKDVLIITVRLCILL 332

  Fly   338 GVLLGYPLQFF---VAIQIMWPNAKQMCGIEGRSLLGELGFRTFMVLVTLAIAEMVPALGLFISL 399
            .|||..||..|   .|:.:|:.:......|  |.:|..|.....:||:.:.:.:|....|    :
Frog   333 AVLLTVPLIHFPARKAVMMMFFSRYPFSYI--RHILVTLVLNIIIVLLAIYVPDMRSVFG----V 391

  Fly   400 IGALCSTALALVFPPVIEL-ISRSELNK------------GPGIWICVKNLVILVLA 443
            :|:..||.|..|||.:..: :.|.:.:.            |..|..|...|:|:.||
Frog   392 VGSTTSTCLLFVFPGLFYVKLGREDCSSPQKFGACGLLVLGICIGACSLTLIIMNLA 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16700	NP_573191.1	SLC5-6-like_sbd	53..452	CDD:294310	92/447 (21%)
CG16700	NP_573191.1	SdaC	57..452	CDD:223884	90/444 (20%)
slc38a6	NP_001008117.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..36
slc38a6	NP_001008117.2	SLC5-6-like_sbd	37..412	CDD:382020	84/409 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D697331at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930