DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16700 and slc38a5b

DIOPT Version :9

Sequence 1:	NP_573191.1	Gene:	CG16700 / 32694	FlyBaseID:	FBgn0030816	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_001002648.1	Gene:	slc38a5b / 436921	ZFINID:	ZDB-GENE-040718-395	Length:	472	Species:	Danio rerio

Alignment Length:	491	Identity:	97/491 - (19%)
Similarity:	191/491 - (38%)	Gaps:	97/491 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 QLEKNQTATVPRQE----TAEGGSTGETAVGGAAAKVTKEQDHDAEYHPPTSYLETIVHLFKGNI 68
            |||:.:  ...|:|    .::||.|.:.                .::...||:..::.:|....:
Zfish    16 QLEEGE--PTEREEFLPHKSDGGKTPQF----------------TDFEGKTSFGMSVFNLSNAIM 62

  Fly    69 GPGLFAMGDAFKNGGLLVAPLLTVVIAVVSIHCQHVLVTCSKKMRDLKGDSVCADYAQTVEQCFE 133
            |.|:..:..|..|.|:::..:|...|||:|.:..|:|:..:       |......|.|..::.|.
Zfish    63 GSGILGLSYAMSNTGIVLFLVLLTCIAVLSSYSVHLLLRSA-------GVVGIRAYEQLGKRAFG 120

  Fly   134 NGPSKLRGWSRTMGRLVDIFICVTQLGFCCIYFVFISTNLKQILQAY--------DIDMNVHLVM 190
            : |.|:         |..:.|.:..:|....|...:...|..::||:        :..:|.:.::
Zfish   121 H-PGKI---------LAAVVITMHNIGAMSSYLFIVKYELPLVIQAFLGLQHSSGEWFLNGNYLI 175

  Fly   191 LLAFVPVLLS-SLITNLKWLTPVSMFANVCMILGLAITLY--------------YALKDGLPEVE 240
            ::..:.::|. :|:..|.:|...|.|:..||:..|...:|              :.:...:..:|
Zfish   176 IIVSISIILPLALMRQLGYLGYTSGFSLTCMVFFLISVIYKKFNIPCPFEDFSNHTVVSNISIIE 240

  Fly   241 ---ERALWTNGSQLALFFGTAIFAFEGIALVMPLKNAMRKPHQFERPLGVLNVGMFLVSVMFMFA 302
               |...:|...|.|.......|||.....|:|:...:|.|.: .|...:.||.:..:.||::..
Zfish   241 GECEAKFFTINQQTAYTVPILAFAFVCHPEVLPIYTELRNPTK-RRMQAIANVSILGMFVMYLLT 304

  Fly   303 GSVGYMKWGEQVGGSL--TLNLGDTI--LAQAVKLMVSAGVLLGYPLQFF----VAIQIMWPN-- 357
            ...||:.:.......|  |.:..|.:  |...|::.|...|.|..|:..|    ..:|:::|.
Zfish   305 AIFGYLTFYLNTEAELLHTYSKVDPLDTLILCVRVAVLVAVTLTVPVVLFPIRRALLQLLFPEKP 369

  Fly   358 ---AKQMCGIEGRSLLGELGFRTFMVLVTLAIAEMVPALGLFISLIGALCSTALALVFPPV--IE 417
               |:            .:.....::.|...:...||.:.....:|||..:.:|..:.|.:  |.
Zfish   370 FHWAR------------HISIALCLLFVVNLLVIFVPNIRDIFGIIGATSAPSLIFILPGLFYIR 422

  Fly   418 LIS--RSELNKGPGIW-ICVKNLVILVLAL-LGFFT 449
            ::|  :..:|..|.|. .|...|..:.:.: |.|.|
Zfish   423 IVSPEQEPMNSRPKILAACFTALGFIFMTMSLTFIT 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16700	NP_573191.1	SLC5-6-like_sbd	53..452	CDD:294310	89/442 (20%)
CG16700	NP_573191.1	SdaC	57..452	CDD:223884	87/438 (20%)
slc38a5b	NP_001002648.1	SLC5-6-like_sbd	46..457	CDD:294310	87/440 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594532
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D697331at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.760