DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16700 and CG13384

DIOPT Version :9

Sequence 1:	NP_573191.1	Gene:	CG16700 / 32694	FlyBaseID:	FBgn0030816	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_723383.1	Gene:	CG13384 / 34160	FlyBaseID:	FBgn0032036	Length:	504	Species:	Drosophila melanogaster

Alignment Length:	454	Identity:	180/454 - (39%)
Similarity:	270/454 - (59%)	Gaps:	16/454 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 NQTATVPRQETAEGGSTGETAVGGAAAKVTKEQDHDAEYHPPTSYLETIVHLFKGNIGPGLFAMG 76
            |....|..:::.....:|:..:|............|.|:  |||..:|:|||.|||||.|:.||.
  Fly    56 NTLVNVHSEDSLAASGSGDDEIGSTDKSYNPTHHRDLEH--PTSNFDTLVHLLKGNIGTGILAMP 118

  Fly    77 DAFKNGGLLVAPLLTVVIAVVSIHCQHVLVTCSKKM-RDLKGDSVCADYAQTVEQCFENGPSKLR 140
            |||||.||.|....|:::..:..||.|:||.||.:: |..:..|:  |:::.....||:||..||
  Fly   119 DAFKNAGLYVGLFGTMIMGAICTHCMHMLVNCSHELCRRFQQPSL--DFSEVAYCSFESGPLGLR 181

  Fly   141 GWSRTMGRLVDIFICVTQLGFCCIYFVFISTNLKQILQAYDIDMNVHLVMLLAFVPVLLSSLITN 205
            .:|....|:|..|:.:||:||||:||:|::.|:|.::..| ..|.|.:.:|:...|::|.:|:.|
  Fly   182 RYSMLARRIVTTFLFITQIGFCCVYFLFVALNIKDVMDHY-YKMPVQIYLLIMLGPMILLNLVRN 245

  Fly   206 LKWLTPVSMFANVCMILGLAITLYYALKDGLPE---VEERALWTNGSQLALFFGTAIFAFEGIAL 267
            ||:|||||:.|.:..:.|||||..|.|.| ||:   |:..|.|   :.|.|:|||||:|||||.:
  Fly   246 LKYLTPVSLVAALLTVAGLAITFSYMLVD-LPDVHTVKPVATW---ATLPLYFGTAIYAFEGIGV 306

  Fly   268 VMPLKNAMRKPHQFERPLGVLNVGMFLVSVMFMFAGSVGYMKWGEQVGGSLTLNL--GDTILAQA 330
            |:||:|.||.|..|....||||.||.:|:.::...|..||:|:||.|.||:||||  ||| |:|.
  Fly   307 VLPLENNMRTPEDFGGTTGVLNTGMVIVACLYTAVGFFGYLKYGEHVEGSITLNLPQGDT-LSQL 370

  Fly   331 VKLMVSAGVLLGYPLQFFVAIQIMWPNAKQMCGIEGRSLLGELGFRTFMVLVTLAIAEMVPALGL 395
            |::.::..:.|.|.|||:|.:.|:.|..:..........|.....|..:|..|..:|..:|.||.
  Fly   371 VRISMAVAIFLSYTLQFYVPVNIVEPFVRSHFDTTRAKDLSATVLRVVLVTFTFLLATCIPNLGS 435

  Fly   396 FISLIGALCSTALALVFPPVIELISRSELNKGPGIWICVKNLVILVLALLGFFTGSYESLKQIV 459
            .|||:||:.|:||||:.||:||:|:...:..|...|:..|:::||:..|.||..|::.||.||:
  Fly   436 IISLVGAVSSSALALIAPPIIEVITFYNVGYGRFNWMLWKDVLILIFGLCGFVFGTWASLAQIL 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16700	NP_573191.1	SLC5-6-like_sbd	53..452	CDD:294310	170/404 (42%)
CG16700	NP_573191.1	SdaC	57..452	CDD:223884	167/400 (42%)
CG13384	NP_723383.1	SdaC	92..484	CDD:223884	167/401 (42%)
CG13384	NP_723383.1	SLC5-6-like_sbd	94..495	CDD:294310	170/410 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468309
Domainoid	1	1.000	157	1.000	Domainoid score	I1306
eggNOG	1	0.900	-	-		E1_COG0814
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1622
Isobase	1	0.950	-	0	Normalized mean entropy	S2463
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm6436
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22950
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R126
SonicParanoid	1	1.000	-	-		X121
	12	11.880