DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16700 and slc38a6

DIOPT Version :9

Sequence 1:	NP_573191.1	Gene:	CG16700 / 32694	FlyBaseID:	FBgn0030816	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_001018308.1	Gene:	slc38a6 / 336741	ZFINID:	ZDB-GENE-050522-51	Length:	449	Species:	Danio rerio

Alignment Length:	424	Identity:	96/424 - (22%)
Similarity:	173/424 - (40%)	Gaps:	56/424 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 TSYLETIVHLFKGNIGPGLFAMGDAFKNGGLLVAPLLTVVIAVVSIHCQH-VLVTCSKKMRDLKG 117
            :|::.:..:|....:|.|:..:..|..|.|.:...:|.:::|.::.:..| :|:.|.|
Zfish    38 SSFMSSAFNLMNAIMGSGILGLSYAMANTGTVGFSILLLMVASLAAYSIHLLLLLCDK------- 95

  Fly   118 DSVCADYAQTVEQCFENGPSKLRGWSRTMGRLVDIFICVTQLGFCCIYFVFISTNLKQILQAYD- 181
             :....|....|:.. |.|.|:         ||...|.:..:|....|...:.|.|...:..:.
Zfish    96 -TGINSYEALGEKAL-NRPGKI---------LVACTILIQNIGAMSSYLFILKTELPAAIIGFMR 149

  Fly   182 ---------IDMNVHLVMLLAFVPVLLSSLITNLKWLTPVSMFANVCMILGLAITLY--YALKDG 235
                     .:..|.|::|:..:.||..:|:..:.:|...|..|.:.|:....:.:.  :::...
Zfish   150 SDSETSGKWFENGVTLLILVTVIIVLPLALLPKIGFLGYTSSIAFLFMLFFTVVVVVKKWSIPCP 214

  Fly   236 LPEVEERALWTN-----------GSQLALFFGTAIFAFEGIALVMPLKNAMRKPHQFERPLGVLN 289
            ||.....:|..|           .|:.|....|..|:|.....|.|:...:.:|.: .|.....|
Zfish   215 LPINSTLSLSLNTSECTAQLFVISSKSAYAVPTMAFSFLCHTAVFPIYCELHRPTK-RRMQRATN 278

  Fly   290 VGMFLVSVMFMFAGSVGYMKWGEQVGGSLTL----NLGDTILAQAVKLMVSAGVLLGYPLQFFVA 350
            |.:||..|:::.:...||:.:...||..|.|    .|...||..:|:|.:...|||..||..|.|
Zfish   279 VSIFLSFVVYLISALFGYLTFYSHVGSELLLAYNTYLPRDILVMSVRLAILLAVLLTVPLIHFPA 343

  Fly   351 IQIMWPNAKQMC-GIEGRSLLGELGFRTFMVLVTLAIAEMVPALGLFISLIGALCSTALALVFPP 414
            .:.:    ..:| |....|.|.......|::.:.|.:|..||.:.....::|:..||.|..|:|.
Zfish   344 RKAV----LMLCRGEREFSWLSHTLSCFFILTLVLLLAIFVPDIKNVFGVVGSTTSTCLLFVYPG 404

  Fly   415 VIELISRSE----LNKGPGIWICVKNLVILVLAL 444
            :..|...||    .|....:::.|..||:.||:|
Zfish   405 MFFLRISSEPIRSFNSVGAVFLLVIGLVVGVLSL 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16700	NP_573191.1	SLC5-6-like_sbd	53..452	CDD:294310	96/424 (23%)
CG16700	NP_573191.1	SdaC	57..452	CDD:223884	95/421 (23%)
slc38a6	NP_001018308.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..25
		SLC5-6-like_sbd	36..443	CDD:294310	96/424 (23%)
		SdaC	37..442	CDD:223884	96/424 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594510
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D697331at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.760