DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16700 and Slc38a2

DIOPT Version :9

Sequence 1:	NP_573191.1	Gene:	CG16700 / 32694	FlyBaseID:	FBgn0030816	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	XP_006242344.1	Gene:	Slc38a2 / 29642	RGDID:	69420	Length:	535	Species:	Rattus norvegicus

Alignment Length:	495	Identity:	101/495 - (20%)
Similarity:	186/495 - (37%)	Gaps:	124/495 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 EQDHDAEYHP-PTSYLETIVHLFKGNIGPGLFAMGDAFKNGGLLVAPLLTVVIAVVSIHCQHVLV 106
            ::.::.::|| .||:..::.:|....:|.|:..:..|..|.|:.:..:|...:::.|::..|:|:
  Rat    59 KKKYETDFHPGTTSFGMSVFNLSNAIVGSGILGLSYAMANTGIALFIILLTFVSIFSLYSVHLLL 123

  Fly   107 TCSKKMRDLKGDSVCADYAQTVEQCFENGPSKLRGWSRTMGRLVDIFICVTQLGFCCIYFVFIST 171
            ..:.     :|.|:.  |.|...:.:     .|.|.....|.     |.:..:|....|...:..
  Rat   124 KTAN-----EGGSLL--YEQLGHKAY-----GLAGKLAASGS-----ITMQNIGAMSSYLFIVKY 171

  Fly   172 NLKQILQAYDIDMNV------------HLVMLLAFVPVLLSSLITNLKWLTPVSMFANVCMILGL 224
            .|..:::|.   ||:            :||:|::||.:|..||:.||.:|...|..:.:|||..|
  Rat   172 ELPLVIKAL---MNIEDTNGLWYLNGDYLVLLVSFVLILPLSLLRNLGYLGYTSGLSLLCMIFFL 233

  Fly   225 ----------------AITLYYAL-------------KDGLPEVEERALWTNGSQLALFFGTAI- 259
                            |::.:.||             |..:|...|.||..|.:....|...|:
  Rat   234 IVVGVVVFVCRKCILKALSGHPALLTSAIFCCQVICKKFQIPCPVEVALMANETVNGTFTQVALA 298

  Fly   260 -------------------------------FAFEGIALVMPLKNAMRKPHQFERPLGVLNVGMF 293
                                           |:|.....|:|:...: |.....|.:.|..:..|
  Rat   299 ALASNSTAADTCRPRYFIFNSQTVYAVPILTFSFVCHPAVLPIYEEL-KSRSRRRMMNVSKISFF 362

  Fly   294 LVSVMFMFAGSVGYMKWGEQVGGSL----TLNLGDTILAQAVKLMVSAGVLLGYPLQFFVAIQIM 354
            .:.:|::.|...||:.:.|.|...|    :..:|..||...|:|.|...|.|..|:..|   .|.
  Rat   363 AMFLMYLLAALFGYLTFYEHVESELLHTYSAIVGTDILLLVVRLAVLVAVTLTVPVVIF---PIR 424

  Fly   355 WPNAKQMCGIEGRSLLGELGFRTFMVLVT-LAIAEM----VPALGLFISLIGALCSTALALVFPP 414
            ......:|..:..|     .||..::.|| ||...:    ||.:......|||..:..|..:.|.
  Rat   425 SSVTHLLCPTKEFS-----WFRHSVITVTILAFTNLLVIFVPTIRDIFGFIGASAAAMLIFILPS 484

  Fly   415 V--IELISRSELNKG----------PGIWICVKNLVILVL 442
            .  |:|:.:..:...          .|:.:.:.::.::||
  Rat   485 AFYIKLVKKEPMRSVQKIGALCFLLSGVVVMIGSMGLIVL 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16700	NP_573191.1	SLC5-6-like_sbd	53..452	CDD:294310	99/484 (20%)
CG16700	NP_573191.1	SdaC	57..452	CDD:223884	97/480 (20%)
Slc38a2	XP_006242344.1	SdaC	64..516	CDD:223884	99/480 (21%)
Slc38a2	XP_006242344.1	SLC5-6-like_sbd	69..518	CDD:294310	97/477 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352587
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750