DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG16700 and Slc36a2

DIOPT Version :9

Sequence 1:	NP_573191.1	Gene:	CG16700 / 32694	FlyBaseID:	FBgn0030816	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_647555.2	Gene:	Slc36a2 / 246235	RGDID:	620492	Length:	481	Species:	Rattus norvegicus

Alignment Length:	463	Identity:	154/463 - (33%)
Similarity:	261/463 - (56%)	Gaps:	61/463 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 AAKVTKEQD---------HDAEYHPPTSYLETIVHLFKGNIGPGLFAMGDAFKNGGLLVAPLLTV 92
            :||..:.||         ..:|.....:..:|:|||.|||:|.|:..:..|.||.|:|:.||..:
  Rat    26 SAKKVQSQDPNPVNGSSSESSEKTKGITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLL 90

  Fly    93 VIAVVSIHCQHVLVTCSKKMRDLKGDSVC-------ADYAQTVEQCFENGPSK-LRG---WSRTM 146
            |:.:::.||.|:||.|:::.        |       .||..||.....:.|:. |:.   |.|
  Rat    91 VMGLIACHCMHILVRCAQRF--------CHRLNKPFMDYGDTVMHGLASSPNTWLQSHAHWGR-- 145

  Fly   147 GRLVDIFICVTQLGFCCIYFVFISTNLKQILQAYD-----------------IDMNVHLVMLLAF 194
             .:|..|:.||||||||:|.||::.||||:::|.:                 ||..::   :|||
  Rat   146 -HVVSFFLIVTQLGFCCVYIVFLADNLKQVVEAVNSTTISCHKNETVVLTPTIDSRLY---MLAF 206

  Fly   195 VPVL-LSSLITNLKWLTPVSMFANVCMILGLAITLYYALKDGLPEVEERALWTNGSQLALFFGTA 258
            :||| |...|.||:.||..|:.|||.|::.|.|...|.:: |:|:..:..|..:.....||||||
  Rat   207 LPVLGLLVFIRNLRVLTIFSLLANVSMLVSLVIIAQYIIQ-GIPDPSQLPLVASWKTYPLFFGTA 270

  Fly   259 IFAFEGIALVMPLKNAMRKPHQFERPLGVLNVGMFLVSVMFMFAGSVGYMKWGEQVGGSLTLNLG 323
            ||:||.|.:|:||:|.|:...:|..   :|::||.:::.:::..|::||:::|:.:..|:||||.
  Rat   271 IFSFESIGVVLPLENKMKDARRFPT---ILSLGMSIITTLYIAIGALGYLRFGDDIKASITLNLP 332

  Fly   324 DTILAQAVKLMVSAGVLLGYPLQFFVAIQIMWPNAKQMCGIEGR-SLLGELGFRTFMVLVTLAIA 387
            :..|.|:|||:...|:|..|.|||:|..:|:.|.|  :..:..| :|..:|..|..:|.:|..:|
  Rat   333 NCWLYQSVKLLYVVGILCTYALQFYVPAEIIIPLA--VSQVSKRWALPVDLSIRLALVCLTCMLA 395

  Fly   388 EMVPALGLFISLIGALCSTALALVFPPVIELISRSELNKGPGIWICVKNLVILVLALLGFFTGSY 452
            .::|.|.|.:||:|::.|:||||:.||::|:  .:...:|.......|:.:|.:|..:||..|:|
  Rat   396 ILIPRLDLVLSLVGSVSSSALALIIPPLLEV--TTYYGEGMSPLTITKDALISILGFMGFVVGTY 458

  Fly   453 ESLKQIVK 460
            ::|.::::
  Rat   459 QALDELIR 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16700	NP_573191.1	SLC5-6-like_sbd	53..452	CDD:294310	147/428 (34%)
CG16700	NP_573191.1	SdaC	57..452	CDD:223884	147/424 (35%)
Slc36a2	NP_647555.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	26..49		5/22 (23%)
Slc36a2	NP_647555.2	SLC5-6-like_sbd	50..461	CDD:382020	148/432 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352579
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm8993
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.820