DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16700 and slc-36.4

DIOPT Version :9

Sequence 1:	NP_573191.1	Gene:	CG16700 / 32694	FlyBaseID:	FBgn0030816	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_492453.1	Gene:	slc-36.4 / 186798	WormBaseID:	WBGene00010421	Length:	481	Species:	Caenorhabditis elegans

Alignment Length:	484	Identity:	127/484 - (26%)
Similarity:	230/484 - (47%)	Gaps:	70/484 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DAEAPNQLEKNQTATVPRQETAEGGSTGETAVGGAAAKVTKEQDHDAEYHPPTSYLETIVHLFKG 66
            |.:.||..:...:..:.|:       ||.:|..|                        :::...|
Worm    42 DRDRPNDTKSVISTLIARK-------TGISATSG------------------------LINFICG 75

  Fly    67 NIGPGLFAMGDAFKNGGLLVAPLLTVVIAVVSIHCQHVLVTCSKKMRDLKGDSVCADYAQTVEQC 131
            .||||.|::..:||..||.....|..::..:|::..|.:|.||:.:....||. ..||.:..|..
Worm    76 MIGPGCFSLAVSFKQAGLWGGLALVFIVGFLSLYSMHKIVNCSQYLAKSNGDQ-SLDYGEMAEAA 139

  Fly   132 FENGPSKLRGWSRTMGRLVDIFI--CVT--QLGFCCIYFVFISTNLKQILQAYDI------DMNV 186
            .:|...    |:|..|:|..|.|  |:.  |||...::.||.   ::.:::.::.      ..:.
Worm   140 MQNSYK----WARKHGKLAKIVINACLLAFQLGVITVFMVFA---VEHVIEIWEFFADSPPPFSK 197

  Fly   187 HLVMLLAFVPVLLSSLITNLKWLTPVSMFANVCMILGLA-ITLYYALKDGLPEVEERALWTNGS- 249
            .:::|:.|||.:|.:.|.::|.||.:.:|.||.:...:. ||....:....|      .|..||
Worm   198 CVMILMYFVPQMLLNFIGHMKLLTILCLFGNVIIFAAIVLITKELMVHTWYP------TWELGSV 256

  Fly   250 ----QLALFFGTAIFAFEGIALVMPLKNAMRKPHQFERPLGVLNVGMFLVSVMFMFAGSVGYMKW 310
                .::|..|..|::|||.|:|:|::|:::.|.......|||:..|.||:|::.|.|..||:.:
Worm   257 TGIEGISLAAGALIYSFEGQAMVLPMENSLKYPKDMTGATGVLSTAMNLVTVLYAFLGFFGYVTF 321

  Fly   311 GEQVGGSLTLNLGDTILAQAVKLMVSAGVLLGYPLQFFVAIQIMWPNAKQMCGIEGRSLLGEL-- 373
            |..|.|||||||.::||..::|.::...:..|..:|.:|.:|::.|:.:.... |.|.::..|
Worm   322 GPAVQGSLTLNLPNSILTVSIKGLLVLKIFFGSAIQLYVIVQMLLPSLRSKIS-EDRKMVHRLLP 385

  Fly   374 -GFRTFMVLVTLAIAEMVPALGLFISLIGALCSTALALVFPPVIE-LISRSELNKGPGIWICVKN 436
             ..|..::|::|.||.:||.|...|.|:|......::|:.|..:: ::......|...::...:.
Worm   386 YALRLGLMLISLCIALIVPNLMQIIPLVGITSGLLISLILPSFLDCMVFLPVFKKQGDMFKFYQK 450

  Fly   437 LVILV-LALLGFF---TGSYESLKQIVKH 461
            |:|.| |.:||:|   .|.|.|:..|:.:
Worm   451 LIINVFLFVLGWFFLGAGLYSSIDDIINN 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16700	NP_573191.1	SLC5-6-like_sbd	53..452	CDD:294310	116/422 (27%)
CG16700	NP_573191.1	SdaC	57..452	CDD:223884	116/418 (28%)
slc-36.4	NP_492453.1	Aa_trans	62..471	CDD:279788	119/447 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166140
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2463
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.810