DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16700 and Slc36a1

DIOPT Version :9

Sequence 1:	NP_573191.1	Gene:	CG16700 / 32694	FlyBaseID:	FBgn0030816	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_569099.1	Gene:	Slc36a1 / 155205	RGDID:	619801	Length:	475	Species:	Rattus norvegicus

Alignment Length:	432	Identity:	165/432 - (38%)
Similarity:	255/432 - (59%)	Gaps:	44/432 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 SYLETIVHLFKGNIGPGLFAMGDAFKNGGLLVAPLLTVVIAVVSIHCQHVLVTCSKKM-RDLKGD 118
            ::.:|::||.|||||.||..:..|.||.|||:.||..:||.:|::||..:||.|:..: |.|  :
  Rat    47 TWFQTLIHLLKGNIGTGLLGLPLAVKNAGLLLGPLSLLVIGIVAVHCMGILVKCAHHLCRRL--N 109

  Fly   119 SVCADYAQTVEQCFENGPSK-LRGWSRTMGRLVDIFICVTQLGFCCIYFVFISTNLKQILQAYD- 181
            ....||..||....|..||. :|..|....|:||.|:.||||||||:||||::.|.||:::|.:
  Rat   110 KPFLDYGDTVMYGLECSPSTWIRNHSHWGRRIVDFFLVVTQLGFCCVYFVFLADNFKQVIEAANG 174

  Fly   182 ----------------IDMNVHLVMLLAFVPVLLSSLITNLKWLTPVSMFANVCMILGLAITLYY 230
                            :|..::::..|.|  ::|.|.|.||:.|:..|:.||:.|.:.| |.:|.
  Rat   175 TTTNCNNNETVILTPTMDSRLYMLTFLPF--LVLLSFIRNLRILSIFSLLANISMFVSL-IMIYQ 236

  Fly   231 ALKDGLPEVEERALWTNGSQLALFFGTAIFAFEGIALVMPLKNAMRKPHQFERPLGVLNVGMFLV 295
            .:...:|:.....|........|||||||||||||.:|:||:|.|:...:|  || :|.:||.::
  Rat   237 FIVQRIPDPSHLPLVAPWKTYPLFFGTAIFAFEGIGVVLPLENKMKDSQKF--PL-ILYLGMAII 298

  Fly   296 SVMFMFAGSVGYMKWGEQVGGSLTLNLGDTILAQAVKLMVSAGVLLGYPLQFFVAIQIMWPNAKQ 360
            :|:::..||:||:::|..:.||:||||.:..|.|:|||:.|.|:...|.|||:||.:|:.|
  Rat   299 TVLYISLGSLGYLQFGADIKGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVAAEIIIP---- 359

  Fly   361 MCGIEGR-----SLLGELGFRTFMVLVTLAIAEMVPALGLFISLIGALCSTALALVFPPVIELIS 420
              .|..|     .|:.:|..||.||.||..:|.::|.|.|.|||:|::.|:||||:.||::|:.:
  Rat   360 --AIVSRVPERFELVVDLSARTAMVCVTCVLAVLIPRLDLVISLVGSVSSSALALIIPPLLEVTT 422

  Fly   421 RSELNKGPGI--WICVKNLVILVLALLGFFTGSYESLKQIVK 460
                ..|.||  ....|:.:|.:|..:||..|:||||.::::
  Rat   423 ----YYGEGISPLTITKDALISILGFVGFVVGTYESLWELIQ 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16700	NP_573191.1	SLC5-6-like_sbd	53..452	CDD:294310	161/422 (38%)
CG16700	NP_573191.1	SdaC	57..452	CDD:223884	161/420 (38%)
Slc36a1	NP_569099.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32
Slc36a1	NP_569099.1	SLC5-6-like_sbd	47..452	CDD:382020	161/422 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352564
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm8993
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.820