DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG16700 and SLC38A9

DIOPT Version :9

Sequence 1:NP_573191.1 Gene:CG16700 / 32694 FlyBaseID:FBgn0030816 Length:468 Species:Drosophila melanogaster
Sequence 2:NP_001336311.1 Gene:SLC38A9 / 153129 HGNCID:26907 Length:561 Species:Homo sapiens


Alignment Length:489 Identity:95/489 - (19%)
Similarity:171/489 - (34%) Gaps:164/489 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    35 GAAAKVTKEQDHDAEYHPPTSYLETIVHLFKGNIGPGLFAMGDAFKNGGLLVAPLLTVVIAVVSI 99
            |:|.|:   |.:...|...|| |.||..::...:|..:.::....|..|......:.:::.::::
Human   102 GSAYKL---QSYTEGYGKNTS-LVTIFMIWNTMMGTSILSIPWGIKQAGFTTGMCVIILMGLLTL 162

  Fly   100 HCQHVLVTCSKKMRDLKGDS-----VCADYAQTVEQCFENGPSKLRGWSRTMGRLVDIFICVTQL 159
            :|.:.:|.....|..|...|     ||..|..:..|           ||..      :|..|:.:
Human   163 YCCYRVVKSRTMMFSLDTTSWEYPDVCRHYFGSFGQ-----------WSSL------LFSLVSLI 210

  Fly   160 GFCCIYFVFISTNL--------KQILQAYDIDMNVHLVMLLAFVPVLLSSLITNLKWLTPVSMFA 216
            |...:|:|.:|..|        ..|....|.|             .:||:..:|     ||    
Human   211 GAMIVYWVLMSNFLFNTGKFIFNFIHHINDTD-------------TILSTNNSN-----PV---- 253

  Fly   217 NVCMILGL------AITLYYALKDGLPEVEERALWTNGSQLALFFGTAIFAFEGIALVMPLKNAM 275
             :|...|.      :..::||...|..:.|:   |.:.|:...|:        .:.|::||.| .
Human   254 -ICPSAGSGGHPDNSSMIFYANDTGAQQFEK---WWDKSRTVPFY--------LVGLLLPLLN-F 305

  Fly   276 RKPHQFER--PLGVLNVGMFLVSVMFMFAGSVGY---MKW--------------GEQVGGSLTL- 320
            :.|..|.:  .||.::| ::|:.::...|..:|:   ..|              ..|:.|.||| 
Human   306 KSPSFFSKFNILGTVSV-LYLIFLVTFKAVRLGFHLEFHWFIPTEFFVPEIRFQFPQLTGVLTLA 369

  Fly   321 -------------------NLGDTILAQAVKLM--VSAGVL------------------------ 340
                               |:.|..:|..:..:  :..|||                        
Human   370 FFIHNCIITLLKNNKKQENNVRDLCIAYMLVTLTYLYIGVLVFASFPSPPLSKDCIEQNFLDNFP 434

  Fly   341 ----LGYPLQFFVAIQIM--WPNAKQMCGIEGR-----SLLGELGFRTFMVLVT--------LAI 386
                |.:..:.|:..|:|  :|    :.|...|     .:.|::....|.||:.        :.:
Human   435 SSDTLSFIARIFLLFQMMTVYP----LLGYLARVQLLGHIFGDIYPSIFHVLILNLIIVGAGVIM 495

  Fly   387 AEMVPALGLFISLIGALCSTALALVFPPVIELIS 420
            |...|.:|..|...||.|..|...::|.:|.:||
Human   496 ACFYPNIGGIIRYSGAACGLAFVFIYPSLIYIIS 529

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG16700NP_573191.1 SLC5-6-like_sbd 53..452 CDD:294310 90/471 (19%)
SdaC 57..452 CDD:223884 88/467 (19%)
SLC38A9NP_001336311.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..30
SLC5-6-like_sbd 115..556 CDD:320982 90/473 (19%)
Important for arginine binding and amino acid transport. /evidence=ECO:0000250|UniProtKB:Q08BA4 129..134 1/4 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165158585
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0814
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.830

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