Protein Alignment CG16700 and SLC32A1

DIOPT Version :10

• Sequence 1: NP_573191.1
• Gene: CG16700 / 32694
• FlyBaseID: FBgn0030816
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_542119.1
• Gene: SLC32A1 / 140679
• HGNCID: 11018
• Length: 525
• Species: Homo sapiens
• Alignment Length: 499
• Identity: 110/499 - (22%)
• Similarity: 199/499 - (39%)
• Gaps: 103/499 - (20%)

  Fly    23 AEGGSTGETAVGGAAAKVTKEQDHDAEYH-------PPTSYLETI--VHLFKGNIGP-------- 70
            |||...|:.   ||.|.|    :.|..|.       ||:...:.:  ...|.|:..|
Human    65 AEGEPCGDE---GAEAPV----EGDIHYQRGSGAPLPPSGSKDQVGGGGEFGGHDKPKITAWEAG 122

  Fly    71 --------GLFAMG--DAFKNGGLLVAPLLTVVIAVVSIHCQHVLVTC---------SKKMRD-- 114
                    |:|.:|  .|..:||.| ...|.:..|||..:...:|:.|         ..::||
Human   123 WNVTNAIQGMFVLGLPYAILHGGYL-GLFLIIFAAVVCCYTGKILIACLYEENEDGEVVRVRDSY 186

  Fly   115 -LKGDSVCADYAQTVEQCFENGPSKLRGWSRTMGRLVDIFICVTQLGFCCIYFVFISTNLKQILQ 178
             ...::.||....|:.                 ||:|:: ..:.:|...||.:|.:|.||
Human   187 VAIANACCAPRFPTLG-----------------GRVVNV-AQIIELVMTCILYVVVSGNL----- 228

  Fly   179 AYD----IDMNVHLVMLLAFVPVLLSSLITNLKWLTPVSMFANVCMILGLAITLY---YALKDGL 236
            .|:    :.::.....::|...:|..:.:.|||   .||.|:.:|.:....|.:.   |.|....
Human   229 MYNSFPGLPVSQKSWSIIATAVLLPCAFLKNLK---AVSKFSLLCTLAHFVINILVIAYCLSRAR 290

  Fly   237 PEVEERA-LWTNGSQLALFFGTAIFAFEGIALVMPLKNAMRKPHQFERPLGVLNVGMFLVSVMFM 300
            ....|:. .:.:..:..:..|..:|::.....:..|:..|::|.:|...:...::...::..:|.
Human   291 DWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFA 355

  Fly   301 FAGSVGYMKWGEQVGGSLTLNLGDTILAQAVKLMVSAGVLLGYPLQFFVAIQIMWPNAKQ----- 360
            .   |.|:.|.::....:|.||..:|.| .|.:.:.|..||.|||.||.|::::..:..|
Human   356 L---VAYLTWADETKEVITDNLPGSIRA-VVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRA 416

  Fly   361 ---MC-GIEGRSLLGELGFRTFMVLVTLAIAEMVPALGLFISLIGALCSTALALVFPPV--IELI 419
               .| ..:||.....|..|..:|:.||.:|..||...|.:.|.|:|....|..:.|.:  :.|:
Human   417 FFPACYSGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLL 481

  Fly   420 SRSELNKGPGIWICV-KNLVILVLALLGFFTGSYESLKQIVKHF 462
            .|..|      |..| .::.|.|:..:...:|...||:.:::.:
Human   482 WRKLL------WHQVFFDVAIFVIGGICSVSGFVHSLEGLIEAY 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16700	NP_573191.1	SLC5-6-like_sbd	53..452	CDD:444915	97/450 (22%)
SLC32A1	NP_542119.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	83..107		3/23 (13%)
		Aa_trans	115..512	CDD:279788	93/433 (21%)