Protein Alignment CG16700 and SLC38A3

DIOPT Version :10

• Sequence 1: NP_573191.1
• Gene: CG16700 / 32694
• FlyBaseID: FBgn0030816
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_006832.1
• Gene: SLC38A3 / 10991
• HGNCID: 18044
• Length: 504
• Species: Homo sapiens
• Alignment Length: 517
• Identity: 115/517 - (22%)
• Similarity: 201/517 - (38%)
• Gaps: 112/517 - (21%)

  Fly     4 EAPNQLEK----------------------NQTATVPRQETAEGGSTGETAVGGAAAKVTKEQDH 46
            |||.|.|.                      ||....|.:...||.|        ...|...::.|
Human     2 EAPLQTEMVELVPNGKHSEGLLPVITPMAGNQRVEDPARSCMEGKS--------FLQKSPSKEPH 58

  Fly    47 DAEYHPPTSYLETIVHLFKGNIGPGLFAMGDAFKNGGLLVAPLLTVVIAVVSIHCQHVLVTCSKK 111
            ..::...||:..::.:|....:|.|:..:..|..|.|:::...|...:|::|.:..|:|
Human    59 FTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLL------ 117

  Fly   112 MRDLKGDSVCA--DYAQTVEQCFENGPSKLRGWSRTMGRLVDIFICVTQLGFCCIYFVFISTNLK 174
               ||...|..  .|.|...:.| ..|.||         ...:.|.:..:|....|...|.:.|.
Human   118 ---LKSSGVVGIRAYEQLGYRAF-GTPGKL---------AAALAITLQNIGAMSSYLYIIKSELP 169

  Fly   175 QILQAY--------DIDMNVHLVMLLAFVPVLLS-SLITNLKWLTPVSMFANVCMILGLAITLY- 229
            .::|.:        |..||.:.:::|..|.::|. :|:..|.:|...|.|:..||:..|...:|
Human   170 LVIQTFLNLEEKTSDWYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYK 234

  Fly   230 -YALKDGLP----------------------EVEERA-------LWTNGSQLALFFGTAIFAFEG 264
             :.:...||                      :||..|       .:|..||.|.......|||..
Human   235 KFHVPCPLPPNFNNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVC 299

  Fly   265 IALVMPLKNAMRKPHQFERPLGVLNVGMFLVSVMFMFAGSVGYMKWGEQVGGSL--TLNLGD--T 325
            ...|:|:...::.|.: ::...:.|:.:.::.:|:..|...||:.:...|...|  |.:..|  .
Human   300 HPEVLPIYTELKDPSK-KKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKVDPFD 363

  Fly   326 ILAQAVKLMVSAGVLLGYPLQFFV---AI-QIMWPNAKQMCGIEGRSLLGELGFRTFMVLVTLAI 386
            :|...|::.|...|.|..|:..|.   || |:::|| ::...:  |.:|..:|..|.:.|:.:..
Human   364 VLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFPN-QEFSWL--RHVLIAVGLLTCINLLVIFA 425

  Fly   387 AEMVPALGLFISLIGALCSTALALVFPPVIEL-ISRSELNKGPGIWICVKNLVILVLALLGF 447
            ..:   ||:| .:|||..:..|..:||.:... |..:|  |.|.  .....::.|..|:|||
Human   426 PNI---LGIF-GVIGATSAPFLIFIFPAIFYFRIMPTE--KEPA--RSTPKILALCFAMLGF 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16700	NP_573191.1	SLC5-6-like_sbd	53..452	CDD:444915	102/446 (23%)
SLC38A3	NP_006832.1	Aa_trans	64..491	CDD:279788	102/447 (23%)