DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8945 and Cpn1

DIOPT Version :9

Sequence 1:	NP_573190.1	Gene:	CG8945 / 32693	FlyBaseID:	FBgn0030815	Length:	1430	Species:	Drosophila melanogaster
Sequence 2:	XP_011245709.1	Gene:	Cpn1 / 93721	MGIID:	2135874	Length:	463	Species:	Mus musculus

Alignment Length:	293	Identity:	72/293 - (24%)
Similarity:	120/293 - (40%)	Gaps:	87/293 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly  1083 PMTWNRYHNHDEIVKYLETVRMRHPQLVELIHIGRSFEGRPLIVVKIESKQTAAAANNDGLHTIK 1147
            |:|: |:|.:|::|:.|..|..:.|.:..|.:||||.:||.|.|::.        ::..|:|...
Mouse    20 PVTF-RHHRYDDLVRTLYKVHNQCPDITRLYNIGRSVKGRYLYVLEF--------SDYPGIHEPL 75

  Fly  1148 RPKRKRKSG-QANAVFVEAGAQGLAWIGPAAATWMIAELLRLMKTNKSNEDVEFIRNTTWYIMPV 1211
            .|:.|.... ..|.|.   |.:.|.         .::|.|.....|::...:..|::|..:|:|.
Mouse    76 EPEVKYVGNMHGNEVL---GRELLL---------QLSEFLCEEFRNRNQRILRLIQDTRIHILPS 128

  Fly  1212 LNPDGYAYSHEYDRFWKKSRSQHQTPPPSGLLDSAMTWLQQKRGPDKVCY--------GVDLDRN 1268
            :|||||          :.:.:|..:|               :.||:...|        ||||:||
Mouse   129 MNPDGY----------EVAAAQVHSP---------------REGPNMSGYLVGRNNANGVDLNRN 168

  Fly  1269 ------WLYHWGKRGSSKAPCNEFYAGPAPFS-----EPETKAVSEFLMDYRTQIKLYISLQAYG 1322
                  :.|:..|.|   .|.:..   |.|.:     ||||:||.:::    ..:...:|...:|
Mouse   169 FPDLNTYFYYNSKNG---GPNHHL---PLPDNWKSQVEPETRAVIQWI----RSLNFVLSANMHG 223

  Fly  1323 --QVISYPVK---------ANSTFNSERLDDFL 1344
              .|.:||..         .:.|.||...||.|
Mouse   224 GAVVANYPYDKSLEHRFRGPHRTSNSPTPDDEL 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8945	NP_573190.1	Propep_M14	988..1058	CDD:280416
CG8945	NP_573190.1	M14_CP_A-B_like	1089..1430	CDD:199844	69/287 (24%)
Cpn1	XP_011245709.1	Peptidase_M14_like	25..343	CDD:386095	69/287 (24%)
Cpn1	XP_011245709.1	Peptidase_M14NE-CP-C_like	347..421	CDD:200604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4063
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950