DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8945 and Agbl4

DIOPT Version :9

Sequence 1:	NP_573190.1	Gene:	CG8945 / 32693	FlyBaseID:	FBgn0030815	Length:	1430	Species:	Drosophila melanogaster
Sequence 2:	XP_011238954.1	Gene:	Agbl4 / 78933	MGIID:	1918244	Length:	552	Species:	Mus musculus

Alignment Length:	387	Identity:	67/387 - (17%)
Similarity:	130/387 - (33%)	Gaps:	157/387 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly  1083 PMTWNRYHNHDEIVKYLETVRMRHPQLVELIHIGRSFEGRPLIVVKIESKQTAAAANNDGLHTIK 1147
            |.|:.|:.:      ||::::.::........:|:|.:.|.|                 .|.||.
Mouse   180 PYTYTRFQH------YLDSLQKKNMDYFFREQLGQSVQQRQL-----------------DLLTIT 221

  Fly  1148 RPKRKRKSGQANAVF----VEAGAQGLAWIGPAAATWMIAE--LLRLMKTNKSNEDVEFIRNTTW 1206
            .|:..|:..:...:|    |..|....:::......:::::  :.|:::           .:..:
Mouse   222 SPENLREGSEKKVIFITGRVHPGETPSSFVCQGIIDFLVSQHPIARVLR-----------EHLVF 275

  Fly  1207 YIMPVLNPDGYAYSHEYDRFWKKSRSQHQTPPPSGLLDSAMTWLQQKRGPDKVC--YGVDLDRNW 1269
            .|.|:||||| .|...|.                                   |  .|.||:|:|
Mouse   276 KIAPMLNPDG-VYLGNYR-----------------------------------CSLMGFDLNRHW 304

  Fly  1270 LYHWGKRGSSKAPCNEFYAGPAPFSEPETKAVSEFLM----DYRTQIKLYISLQAYGQVISYPVK 1330
            |                  .|:|::.|....|.:.::    |.:|.::.||.:.|:..:::..:.
Mouse   305 L------------------DPSPWAHPTLHGVKQLIIKMYNDPKTSLEFYIDIHAHSTMMNGFMY 351

  Fly  1331 ANSTFNSERL--------------DDF--------LDVAMVGTDGLRKKGSKSRYKVDASNDLIE 1373
            .|...:.||.              :||        .|....|| |.|..|.           |::
Mouse   352 GNIFEDEERFQRQSIFPKLLCQNAEDFSYTSTSFNRDAVKAGT-GRRFLGG-----------LLD 404

  Fly  1374 QRSGCADAFAAYEIGIPFSYTLQLADNGVHGYLL-PSSAIEPTARDAF-----EIISGMLDY 1429
            ..|.|              |||:::   .:.|:: .::|..|...:|:     .:....|||
Mouse   405 HSSYC--------------YTLEVS---FYSYIIGGTTAAVPYTEEAYMKLGRNVARTFLDY 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8945	NP_573190.1	Propep_M14	988..1058	CDD:280416
CG8945	NP_573190.1	M14_CP_A-B_like	1089..1430	CDD:199844	64/381 (17%)
Agbl4	XP_011238954.1	Pepdidase_M14_N	65..>142	CDD:375499
Agbl4	XP_011238954.1	M14_AGBL4_like	199..450	CDD:349479	62/362 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900