back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8945 and Cpa5

DIOPT Version :9

Sequence 1:	NP_573190.1	Gene:	CG8945 / 32693	FlyBaseID:	FBgn0030815	Length:	1430	Species:	Drosophila melanogaster
Sequence 2:	NP_653120.1	Gene:	Cpa5 / 74649	MGIID:	1921899	Length:	436	Species:	Mus musculus

Alignment Length:	466	Identity:	125/466 - (26%)
Similarity:	217/466 - (46%)	Gaps:	83/466 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   978 RISYDKYQIWRLKPQDEEQVRALEEFKKGEDGVKLQWLKGPSLRGL-TDVLVPPKMLVDFQGTLN 1041
            ::::...|:.|:..::|:|:..|.:.:. :...|:.:.:||:...| .|:.||...|...:..|.
Mouse    34 QVNFTGDQVLRVLAKNEKQLSLLRDLET-QKPQKVDFWRGPARPSLPVDMRVPFSELPSVKAYLK 97

  Fly  1042 YEGIAHEVLIFDVGKAIAYE---LTKEDYLQTTRPSKPRPTAPPPMTWNRYHNHDEIVKYLETVR 1103
            ..|:|:.::|.|:...:..|   :.|...|:.:..|         .:::.||..|||..:::...
Mouse    98 SHGLAYSIMIKDIQVLLDEERDAMAKSRRLERSTNS---------FSYSSYHTLDEIYSWIDNFV 153

  Fly  1104 MRHPQLVELIHIGRSFEGRPLIVVKIESKQTAAAANNDGLHTIKRPKRKRKSGQANAVFVEAGAQ 1168
            ..|..||..||||:|||.|.::|:|.    :....|        ||          |::::.|..
Mouse   154 AEHSNLVSKIHIGKSFENRSILVLKF----STGGPN--------RP----------AIWIDTGIH 196

  Fly  1169 GLAWIGPAAATWMIAELLRLMKTNKSNED--VEFIRNT-TWYIMPVLNPDGYAYSHEYDRFWKKS 1230
            ...||..|...|:..:::     |...:|  ::.|.|| ..:|..|.||||:|::|..:|.|:|:
Mouse   197 SREWITHATGIWISQKIV-----NAYGKDHVLKRILNTMDIFIEIVTNPDGFAFTHSMNRLWRKN 256

  Fly  1231 RSQHQTPPPSGLLDSAMTWLQQKRGPDKVCYGVDLDRNWLYHWGKRGSSKAPCNEFYAGPAPFSE 1295
            :|..                     |...|.||||:|||...:|..||:|.||:|.|.||||.||
Mouse   257 KSSQ---------------------PGIFCIGVDLNRNWKAGFGGNGSNKNPCSETYRGPAPESE 300

  Fly  1296 PETKAVSEFLMDYRTQIKLYISLQAYGQVISYPVKANSTFNSERLDDFLDVAMVGTDGLRKK--- 1357
            ||..|:.:|:..: ...|..||:.:|.|::.||. .:|.......::..::|......|.|.
Mouse   301 PEVAAIVDFITGH-GNFKAMISIHSYSQMVMYPY-GHSLEPVPNHEELFNLAKDAVKALNKVHGI 363

  Fly  1358 ----GSKSRYKVDASNDLIEQRSGCADAFAAYEIGIPFSYTLQLADNGVHGYLLPSSAIEPTARD 1418
                ||.|.....||...::.         ||:.||.::::.:|.|.|.:|:|||:|.|.|||.:
Mouse   364 QYIFGSISTTLYSASGISVDW---------AYDSGIKYAFSFELRDTGQYGFLLPASQIVPTAEE 419

  Fly  1419 AFEIISGMLDY 1429
            .:..:..::.:
Mouse   420 TWMALQTIMKH 430

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.