Protein Alignment CG8945 and Agtpbp1

DIOPT Version :10

• Sequence 1: NP_573190.1
• Gene: CG8945 / 32693
• FlyBaseID: FBgn0030815
• Length: 1430
• Species: Drosophila melanogaster
• Sequence 2: NP_075817.2
• Gene: Agtpbp1 / 67269
• MGIID: 2159437
• Length: 1218
• Species: Mus musculus
• Alignment Length: 1241
• Identity: 228/1241 - (18%)
• Similarity: 371/1241 - (29%)
• Gaps: 488/1241 - (39%)

  Fly   420 GPLHAKKRNSSLK--ALIKKSVLKNAVKRARLLKNQGEMDSSRT----QHRRSRRSLYSIKNGEI 478
            ||.  .|:||.|.  ||...:.|..:...||...::|.:....|    .||...|.    :|..|
Mouse   210 GPF--SKKNSGLMKVALDTLAALLKSKTNARRAVDRGYVQVLLTIYVDWHRHDNRH----RNMLI 268

  Fly   479 EKSIKTEKATKVPSEEAEKEVTADSTKRSQKV-VSKESKTILSRGNPNVVAAR------------ 530
            .|.|.          ::.|.||  :.|..:|. :......||...:...:|.|
Mouse   269 RKGIL----------QSLKSVT--NIKLGRKAFIDANGMKILYNTSQECLAVRTLDPLVNTSSLI 321

  Fly   531 -RVSTPKRRSPKGSSGRRKTKQQTPPSTQKKEKNSGGVLHIPTALHLLHRNHSQDEVPKVPLNAN 594
             |...||.|.|                             :||.....|     .::|.:|:..
Mouse   322 MRKCFPKNRLP-----------------------------LPTIKSSFH-----FQLPIIPVTG- 351

  Fly   595 QKKKRKVKERKRGRPQLPSFDIFELMSDGDYEDEGEEEEEEQDDDEDYYFEDEHKDEDKNK--PN 657
                 .|.:.....|::.  |:.:...|.|..|...|.|.|.:||.|..|:::..:.|.||  |.
Mouse   352 -----PVAQLYSLPPEVD--DVVDESDDNDDIDLEVENELENEDDLDQSFKNDDIETDINKLRPQ 409

  Fly   658 ESSSTEVGQ--------SDLKEDSSSAE-----------EGADFGAMVEEETTTTATISSSEELD 703
            :.....:.:        .:|.:|....|           ||...|.:|        ..::.||:.
Mouse   410 QVPGRTIEELKMYEHLFPELVDDFQDYELISKEPKPFVFEGKARGPIV--------VPTAGEEVP 466

  Fly   704 ATSSTKNSMAKKKIRIKRRPVDSDEDYDDDEDSGIAGFFRMIFYPVQV-AMSRLMDGFGTPDEEE 767
            ..|.:    .||.:.:|.|.....|:..:|.    .|..|.:  |.|: ..||:..
Mouse   467 GNSGS----VKKGVVMKERASPKGEEAKEDP----KGHDRTL--PQQLGGQSRVAP--------- 512

  Fly   768 DKEPATQPVSKYPSYTLYHSAHS-NEAYAEPDDE---DSEDDEDSSSLGSWFGSWFGLQRRTKKI 828
                               |||| |....:..|.   .:...:.:|.|.:.....|||
Mouse   513 -------------------SAHSFNNDLVKALDRITLQNVPSQVASGLNAGMRKDFGL------- 551

  Fly   829 GSTTTTMPVPLPPPTKAPPSWLESWFGFGST--------------TEADAEDDYDKWFSSWFDSR 879
                   |:.:...|||.|...:.    |||              |..:.|||.|
Mouse   552 -------PLTVLSCTKACPHVAKC----GSTLFEGRTVHLGKLCCTGVETEDDED---------- 595

  Fly   880 PKRKFRRRSTTSTSTTSTTTTTHTPSAAAAQVPILTIVDPLRNPQNWIGILAHHIVNSTGSA--- 941
                          |.|.::|...||..|:..|      .|.:|..:|     .||.:|.|.
Mouse   596 --------------TESHSSTEQAPSVEASDGP------TLHDPDLYI-----EIVKNTKSVPEY 635

  Fly   942 -----------ISTSTSNPLLQALATRMTTRGTTSTTTTTSRPDVPRRISYDKYQIWRLKPQDEE 995
                       |......|:|:.......|:..........:.|:..|:.||........|::.:
Mouse   636 SEVAYPDYFGHIPPPFKEPILERPYGVQRTKIAQDIERLIHQNDIIDRVVYDLDNPTYTTPEEGD 700

  Fly   996 QVRALEEFKKGEDGVKLQWLKGPSLRGLTDVLVPPKMLVDFQGTLNYEGIAHEVLIFDVG---KA 1057
            .::...:|:.|            :||.:..:......|: ....:| ....|:...|:|.   ..
Mouse   701 TLKFNSKFESG------------NLRKVIQIRKSEYDLI-LNSDIN-SNHYHQWFYFEVSGMRPG 751

  Fly  1058 IAY-------ELTKEDYLQTTRP--------SKPRPTAPPPMTWNR-------YHNH-------- 1092
            :||       |.:...:....:|        ...||      .|.|       |.||
Mouse   752 VAYRFNIINCEKSNSQFNYGMQPLMYSVQEALNARP------WWIRMGTDICYYKNHFSRSSVAA 810

  Fly  1093 --------------------DEIVKY-------LETVRMRHPQLVELIH-----------IGRSF 1119
                                |::..:       ..|::| |.|.:|..|           :..:.
Mouse   811 GGQKGKSYYTITFTVNFPHKDDVCYFAYHYPYTYSTLQM-HLQKLESAHNPQQIYFRKDVLCETL 874

  Fly  1120 EGR--PLIVVKIESKQTAAAANNDGLHTIK---RPKRKRKSGQANAVFVEAGAQGLAWIGPAAAT 1179
            .|.  ||:.:      ||...:|...|..:   ||          .:|:.|....    |...|:
Mouse   875 SGNICPLVTI------TAMPESNYYEHICQFRTRP----------YIFLSARVHP----GETNAS 919

  Fly  1180 WMIAELLRLMKTNKSNEDVEFIRNT-TWYIMPVLNPDGYAY-SHEYDRFWKKSRSQHQTPPP--- 1239
            |::...|..:.:|  :...:.:|.: .:.|:|:|||||... :|......:....|.|:|.|
Mouse   920 WVMKGTLEYLMSN--SPTAQSLRESYIFKIVPMLNPDGVINGNHRCSLSGEDLNRQWQSPNPELH 982

  Fly  1240 ------SGLLD--SAMTWLQQKRGPDKVC-------------YGVDLDRN-WLYHWGKRGSSKAP 1282
                  .|||.  :|:     ||.|...|             ||..:... |..|     .:.|.
Mouse   983 PTIYHAKGLLQYLAAV-----KRLPLVYCDYHGHSRKKNVFMYGCSIKETVWHTH-----DNSAS 1037

  Fly  1283 CNEFYAGPAPFSEPETKAVSEFLMDYRTQIKLYI-----------------SLQAYGQVI----- 1325
            |:               .|.:  |.|||..|:..                 |.::..:|:
Mouse  1038 CD---------------IVED--MGYRTLPKILSHIAPAFCMSSCSFVVEKSKESTARVVVWREI 1085

  Fly  1326 ----SYPVKA-----------NSTFNSERLDDFLDVAMVGTDGLRKKGSKSRYK-----VDASND 1370
                ||.:::           .....:..|::......||...|::..|...|.     :|..||
Mouse  1086 GVQRSYTMESTLCGCDQGRYKGLQIGTRELEEMGAKFCVGLLRLKRLTSSLEYNLPSNLLDFEND 1150

  Fly  1371 LIEQRSGCADAFAAYEIGIPFSYTL-----------------------QLADNGVHGYLLPSSAI 1412
            |||  |.|       ::..|.:|.|                       :||:|        :...
Mouse  1151 LIE--SSC-------KVTSPTTYVLDEDEPRFLEEVDYSAESNDELDVELAEN--------TGDY 1198

  Fly  1413 EPTARD 1418
            ||:|::
Mouse  1199 EPSAQE 1204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8945	NP_573190.1	PHA03175	396..>525	CDD:177551	27/111 (24%)
		Propep_M14	987..1061	CDD:460505	12/83 (14%)
		Peptidase_M14	1095..1421	CDD:459730	82/439 (19%)
Agtpbp1	NP_075817.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	476..512		10/41 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	590..617		11/56 (20%)
		Pepdidase_M14_N	704..838	CDD:407865	21/153 (14%)
		M14_Nna1	861..1131	CDD:349477	57/318 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1193..1218		4/20 (20%)