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Protein Alignment CG8945 and CPA6

DIOPT Version :9

Sequence 1:	NP_573190.1	Gene:	CG8945 / 32693	FlyBaseID:	FBgn0030815	Length:	1430	Species:	Drosophila melanogaster
Sequence 2:	NP_065094.3	Gene:	CPA6 / 57094	HGNCID:	17245	Length:	437	Species:	Homo sapiens

Alignment Length:	458	Identity:	136/458 - (29%)
Similarity:	211/458 - (46%)	Gaps:	90/458 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   978 RISYDKYQIWRLKPQDEEQVRALEEFKKGEDGVKLQWLKGPSLR-----GLTDVLVP---PKMLV 1034
            |.:.||  :.|..|:.||:..||   ||....:|:...:..|:.     .:|||.:|   .:.|:
Human    36 RYAGDK--VIRFIPKTEEEAYAL---KKISYQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRALL 95

  Fly  1035 DFQGTLNYEGIAHEVLIFDVGKAIAYELTKEDYLQTTRPSKPRPTAPPPMTWNRYHNHDEIVKYL 1099
            .|   |....|.::|||.|:.|.    |.|...|.|.|..:    :.....:..||:.:||..::
Human    96 AF---LQEANIQYKVLIEDLQKT----LEKGSSLHTQRNRR----SLSGYNYEVYHSLEEIQNWM 149

  Fly  1100 ETVRMRHPQLVELIHIGRSFEGRPLIVVKIESKQTAAAANNDGLHTIKRPKRKRKSGQANAVFVE 1164
            ..:...|..|:.:..||||:|||.|.::|:.                :|.:.||      ||:::
Human   150 HHLNKTHSGLIHMFSIGRSYEGRSLFILKLG----------------RRSRLKR------AVWID 192

  Fly  1165 AGAQGLAWIGPAAATWMIAELLRLMKTNKSNEDVEFIRNTTWYIMPVLNPDGYAYSHEYDRFWKK 1229
            .|.....|||||...|.:.|.|...|::.:..  :.:.:..:|||||.|.|||.:|...||||:|
Human   193 CGIHAREWIGPAFCQWFVKEALLTYKSDPAMR--KMLNHLYFYIMPVFNVDGYHFSWTNDRFWRK 255

  Fly  1230 SRSQHQTPPPSGLLDSAMTWLQQKRGPDKVCYGVDLDRNWLYHWGKRGSSKAPCNEFYAGPAPFS 1294
            :||                     |.....|.|||.:|||...|...|:|..||::.|.||.|.|
Human   256 TRS---------------------RNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPES 299

  Fly  1295 EPETKAVSEFLMDYRTQIKLYISLQAYGQVISYPVKANSTFNSERLDDFLDV---------AMVG 1350
            |||.|||:.||..:|..|:.|:|..||.|::.||.    ::....:.:|..|         |:..
Human   300 EPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPY----SYKYATIPNFRCVESAAYKAVNALQS 360

  Fly  1351 TDGLRKKGSKSRYKVDASNDLIEQRSGCADAFAAYEIGIPFSYTLQLADNGVHGYLLPSSAIEPT 1415
            ..|:       ||:...::..:...||.:..: ||:.|||:::..:|.|.|..|:|||...|:||
Human   361 VYGV-------RYRYGPASTTLYVSSGSSMDW-AYKNGIPYAFAFELRDTGYFGFLLPEMLIKPT 417

  Fly  1416 ARD 1418
            ..:
Human   418 CTE 420

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.