DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8945 and CG4408

DIOPT Version :10

Sequence 1:NP_573190.1 Gene:CG8945 / 32693 FlyBaseID:FBgn0030815 Length:1430 Species:Drosophila melanogaster
Sequence 2:NP_651141.2 Gene:CG4408 / 42762 FlyBaseID:FBgn0039073 Length:479 Species:Drosophila melanogaster


Alignment Length:509 Identity:141/509 - (27%)
Similarity:238/509 - (46%) Gaps:85/509 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   923 PQNWIGILAHHIVNSTGSAISTSTSNPLLQALATRMTTRGTTSTTTTTSRPDVPRRISYDKYQIW 987
            |:.|:.:|   :|:|......:..|:...:|....:.....|:..:..:|        ||..:|:
  Fly    34 PKTWLLLL---LVSSVCVIQESKASSFCTKADQCALDEEIKTAADSVQAR--------YDHTRIY 87

  Fly   988 RLKPQDEEQVRALEEFKKGEDGVKLQWLKGPSLRGLTDVLVPPKMLVDFQGTLNYEGIAHEVLIF 1052
            :::...||.||..:..::..|............:.|| ::|....:.||...::...:.|.||.:
  Fly    88 QVELASEEHVRLFQALEQASDSCSFMGHARQPGQKLT-IMVTGAKVADFDDLVHSYNVTHRVLNY 151

  Fly  1053 DVGKAIAYELTKEDYLQTTRPSKPRPTAPPPMTWNRYHNHDEIVKYLETVRMRHPQLVELIHIGR 1117
            :.     ..|...:||:..    |..|.|....|.|||..:.|..:|:.:...||::: |:.:|.
  Fly   152 NF-----QALIDANYLEVA----PEDTKPEEFDWKRYHPLESINAWLKKLAETHPEVL-LVELGV 206

  Fly  1118 SFEGRPLIVVKIESKQTAAAANNDGLHTIKRPKRKRKSGQANAVFVEAGAQGLAWIGPAAATWMI 1182
            |.:|||::.|:|       |.:|:...|               ||||:|.....||.||.||::|
  Fly   207 SAQGRPILGVQI-------AFDNENRTT---------------VFVESGIHAREWIAPATATYII 249

  Fly  1183 AELLRLMKTNKSNEDVEFI-RNTTWYIMPVLNPDGYAYSHEYDRFWKKSRSQHQTPPPSGLLDSA 1246
            .:|:     |..:..|:.: |:..|||.|.:|||||.|:.:.||.|:|:|:..            
  Fly   250 DQLV-----NSKDSAVQALARSQRWYIFPTVNPDGYQYTFKGDRMWRKNRALF------------ 297

  Fly  1247 MTWLQQKRGPDKVCYGVDLDRNWLYHWGKRGSSKAPCNEFYAGPAPFSEPETKAVSEFLMDYRTQ 1311
                       .:|.||||:||:.:||...|:|..||...|:||:..||.||:.:.||:. :|.:
  Fly   298 -----------GICRGVDLNRNFPFHWNVTGASGDPCRYDYSGPSAASEVETQRMIEFIR-HRVE 350

  Fly  1312 ---IKLYISLQAYGQVISYPVKANSTFNSERLDDFLDVAMVGTDGLRK-KGSKSR-YKVDASNDL 1371
               |:.:|||.:|.|:|.:|.    ..::||:|::.|:..:|.....| |....| ||..:..:.
  Fly   351 SERIRTFISLHSYSQMIMFPY----GHSAERVDNYHDLTDIGKLAANKIKDVSGRIYKSGSIYET 411

  Fly  1372 IEQRSGCADAFAAYEIGIP--FSYTLQLADNGVHGYLLPSSAIEPTARDAFEII 1423
            |...||.:..:|..::.||  |||.|:...:....::|.:..|||||.:||..|
  Fly   412 IYPSSGGSKDWAHGQLKIPITFSYELRGPADSEDLFILSAKEIEPTAAEAFASI 465

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8945NP_573190.1 PHA03175 396..>525 CDD:177551
Propep_M14 987..1061 CDD:460505 13/73 (18%)
Peptidase_M14 1095..1421 CDD:459730 104/333 (31%)
CG4408NP_651141.2 Propep_M14 87..159 CDD:460505 14/77 (18%)
M14_CP_A-B_like 179..466 CDD:349433 108/343 (31%)
Blue background indicates that the domain is not in the aligned region.

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