DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8945 and CG8539

DIOPT Version :9

Sequence 1:	NP_573190.1	Gene:	CG8945 / 32693	FlyBaseID:	FBgn0030815	Length:	1430	Species:	Drosophila melanogaster
Sequence 2:	NP_001261520.1	Gene:	CG8539 / 38842	FlyBaseID:	FBgn0035791	Length:	385	Species:	Drosophila melanogaster

Alignment Length:	358	Identity:	90/358 - (25%)
Similarity:	146/358 - (40%)	Gaps:	102/358 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly  1087 NRYHNHDEIVKYLETVRMRHPQLVELIHIGRSFEGRPLIVVKIESKQTAAAANNDGLHTIKRPKR 1151
            :.|.::|.|::||:.:.:.|...|.|..:.|::|.|.|        :.|...|.||     ||.:
  Fly    36 DNYLSYDGIMQYLDELALSHSNRVTLKDVARTYENRAL--------KMAIITNGDG-----RPGK 87

  Fly  1152 KRKSGQANAVFVEAGAQGLAWIGPAAATWMIAELLRLMKTNKSNEDVEFIRNT------TWYIMP 1210
            :       .:|::|......|:.||||...|.:|:           |||..|:      .|:|||
  Fly    88 R-------VIFLDAALHSREWMTPAAALLTIHKLV-----------VEFAENSDLLTDYDWHIMP 134

  Fly  1211 VLNPDGYAYSHEYDRFWKKSRSQHQTPPPSGLLDSAMTWLQQKRGPDKVCYGVDLDRNWLYHWGK 1275
            :.|||||.||...:|:|:.:|:      |:|                ..|:|.:|:||:...|..
  Fly   135 LANPDGYEYSRNTERYWRNTRT------PNG----------------GNCFGTNLNRNFAVDWNV 177

  Fly  1276 R-GSSKAPCNEFYAGPAPFSEPETKAVSEF---LMDYRTQIKLYISLQAYGQVISYP--VKANST 1334
            . ...|.||:|.|||.:||||.|.:.|.:.   |::.:..: :|:||....:.:.||  ...:..
  Fly   178 GFPELKDPCDENYAGSSPFSEVEARTVRDIMHGLVESKRAV-MYLSLHTANRSVFYPWVYDTDPV 241

  Fly  1335 FNSERLDDF----LDVAMVGTDGLRKKGSKSRYKVDASNDLIEQRSGCADAFA------AYEIGI 1389
            .|.:..|:.    .|..:..|....|....::|               |..|.      |...|.
  Fly   242 SNQKEHDEIGRFVADRILQSTGTFIKTWQYAKY---------------AGTFGGTSMDYALLAGF 291

  Fly  1390 PFSYTLQLADNGVHGYLLPSSAIE----PTARD 1418
            |.|:..:::..|       ...:|    |.|||
  Fly   292 PLSFVFEMSGTG-------RDHVEYKFFPPARD 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8945	NP_573190.1	Propep_M14	988..1058	CDD:280416
CG8945	NP_573190.1	M14_CP_A-B_like	1089..1430	CDD:199844	90/356 (25%)
CG8539	NP_001261520.1	M14_CP_A-B_like	38..335	CDD:199844	90/356 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920