DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8945 and CG7025

DIOPT Version :9

Sequence 1:	NP_573190.1	Gene:	CG8945 / 32693	FlyBaseID:	FBgn0030815	Length:	1430	Species:	Drosophila melanogaster
Sequence 2:	NP_609133.2	Gene:	CG7025 / 34042	FlyBaseID:	FBgn0031930	Length:	429	Species:	Drosophila melanogaster

Alignment Length:	453	Identity:	118/453 - (26%)
Similarity:	208/453 - (45%)	Gaps:	65/453 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   978 RISYDKYQIWRLKPQDEEQVRALEEFKKGEDGVKLQWLKGPSLRGLTDVLVPPKMLVDFQGTLNY 1042
            |:.||.|.::::|.:.:.|...|.:..:..:..:| |.:.   :....:::.|....:.:..:..
  Fly    26 RLRYDNYSVYKVKFETQAQRSILRKLAEDRENFRL-WHEA---KDELHLMLSPGAFGELETEIQK 86

  Fly  1043 EGIAHEVLIFDVGKAIAYELTKEDYLQTTRPSKPRPTAPPPMTWNRYHNHDEIVKYLETVRMRHP 1107
            ..:..|:.|.:|          ::.:.:...:..:.:......|.:|::..||..:|:.:...:|
  Fly    87 TNVTAELFISNV----------QELIDSEEAANLKASRDGTFGWTKYNSLAEIYAWLDDILAAYP 141

  Fly  1108 QLVELIHIGRSFEGRPLIVVKIESKQTAAAANNDGLHTIKRPKRKRKSGQANAVFVEAGAQGLAW 1172
            .:.|...:|:|:|||.:..:||..|     :||.|                  |.:|:......|
  Fly   142 TITESFIVGQSYEGRTIRGIKISYK-----SNNPG------------------VLIESNIHAREW 183

  Fly  1173 IGPAAATWMIAELLRLMKTNKSNEDV-EFIRNTTWYIMPVLNPDGYAYSHEYDRFWKKSRSQHQT 1236
            |..|.|||:|.|.|     ..::|.| :...|..|||:||||.||:.|:||.||.|:|:|.
  Fly   184 ITSATATWLINEFL-----TSTDELVRDLAENHDWYIVPVLNVDGFVYTHEKDRMWRKTRQ---- 239

  Fly  1237 PPPSGLLDSAMTWLQQKRGPDKVCYGVDLDRNWLYHW-GKRGSSKAPCNEFYAGPAPFSEPETKA 1300
              ||.:               ..|.|.|.:||:..|| ...|:|..||.|.|.||.||||||.:|
  Fly   240 --PSEI---------------SSCIGADPNRNYDSHWMENEGASSNPCAEDYGGPKPFSEPEIQA 287

  Fly  1301 VSEFLMDYRTQIKLYISLQAYGQVISYPVKANSTFNSERLDDFLDVAMVGTDGLRKKGSKSRYKV 1365
            :|||::..:.:|.:.::..:|.|::..|............||.::||....|.:......:.|:.
  Fly   288 MSEFVISIKDKINVLLAFHSYSQLLLSPYGHTKEEFPPNFDDMMEVAKAYGDAVESLPYGTVYRY 352

  Fly  1366 DASNDLIEQRSGCADAFAAYEIGIPFSYTLQLADNGVHGYLLPSSAIEPTARDAFEIISGMLD 1428
            .::..::...||....:|..|.|:..|||::..|.|.:|::||...|.|.|.:|...|:.:|:
  Fly   353 GSAAGILYPASGATIDWAYNEQGVEISYTIEFRDTGRYGFILPPVHIIPNAEEALIGIAALLE 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8945	NP_573190.1	Propep_M14	988..1058	CDD:280416	9/69 (13%)
CG8945	NP_573190.1	M14_CP_A-B_like	1089..1430	CDD:199844	104/342 (30%)
CG7025	NP_609133.2	Propep_M14	36..103	CDD:280416	9/80 (11%)
CG7025	NP_609133.2	M14_CP_A-B_like	123..416	CDD:199844	104/342 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920