DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8945 and CG3097

DIOPT Version :9

Sequence 1:	NP_573190.1	Gene:	CG8945 / 32693	FlyBaseID:	FBgn0030815	Length:	1430	Species:	Drosophila melanogaster
Sequence 2:	NP_572259.1	Gene:	CG3097 / 31503	FlyBaseID:	FBgn0029804	Length:	445	Species:	Drosophila melanogaster

Alignment Length:	504	Identity:	138/504 - (27%)
Similarity:	237/504 - (47%)	Gaps:	106/504 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   940 SAISTSTSNPLLQALATRMTTRGTTSTTTTTSRPDVPRRISYDKYQIWRLKPQDEEQVRALEEFK 1004
            :|::.|.:|.|             .|..|.....::|:|  ||:.|:||:....|    |::  |
  Fly    15 AAVAASLANEL-------------PSNLTLLDANEIPQR--YDEAQLWRIYNISE----AMQ--K 58

  Fly  1005 KGEDGVKLQWLKGPSL----RGLTDVLVPPKMLVDFQGTLNYEGIAHEVLIFDVGKAIAYELTKE 1065
            :...|..|:...|.::    ....|:.:....|...:..|:...:..::|..::...|..||.
  Fly    59 RVPVGQMLEQKFGGNIWKENSKFLDISIARDQLKAARSFLSAHRLDPQILSHNIQSMIDEELL-- 121

  Fly  1066 DYLQTTRPSKPRPT---APPPMTWNRYHNHDEIVKYLETVRMRHPQLVELIHIGRSFEGRPLIVV 1127
            :.:|::.....|.|   |...|.|..||:.:.|..::..:|.:.|.:|.|..||::.|||.|.|:
  Fly   122 EGIQSSSFGHGRRTKKAARSSMHWKDYHDLETIYSFMREIRTKFPNIVRLYTIGQTAEGRDLKVL 186

  Fly  1128 KIESKQTAAAANNDGLHTIKRPKRKRKSGQANAVFVEAGAQGLAWIGPAAATWMIAELLRLMKTN 1192
            :|.                :.|:..:|      |:::.|.....||.||..|:::.:|:    ::
  Fly   187 RIS----------------ENPRENKK------VWIDGGIHAREWISPATVTFILYQLM----SD 225

  Fly  1193 KSNEDVEFIRNTTWYIMPVLNPDGYAYSHEYDRFWKKSRSQHQTPPPSGLLDSAMTWLQQKRGPD 1257
            ..|:... ||..|||||||:|||||.||...:|.|:|:||      ||            :|..
  Fly   226 WENQPAH-IRGLTWYIMPVMNPDGYEYSRTTNRLWRKNRS------PS------------RRAQ- 270

  Fly  1258 KVCYGVDLDRNWLYHWGKRGSSKAPCNEFYAGPAPFSEPETKAVSEFLMDYRTQIKLYISLQAYG 1322
              |.||||:||:...|...|||..||::.|.|.||.||.||:||:|||...:..::.|::..:||
  Fly   271 --CSGVDLNRNFDIGWNGYGSSTNPCSDTYRGSAPASERETRAVAEFLAKRKYNLESYLTFHSYG 333

  Fly  1323 QVISYP-----VKAN--------STFNSERLDDFLDVAMVGTDGLRKKGSKSRYKVDASNDLIEQ 1374
            |:|.||     ||..        |:..:||:             |:|.|:.  |:...:::::..
  Fly   334 QMIVYPWAYKAVKVKDASVLQRVSSLAAERI-------------LQKTGTS--YRAAVTHEVLGI 383

  Fly  1375 RSGCADAFAAYEIGIPFSYTLQLADNGVHGYLLPSSAIEPTARDAFEII 1423
            ..|.:|.::...:|:.:.||::|.|.|.:|::||...|:.||.:.:.::
  Fly   384 AGGGSDDWSRAALGVKYVYTIELRDRGAYGFVLPPRFIKDTALEGWTVV 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8945	NP_573190.1	Propep_M14	988..1058	CDD:280416	11/73 (15%)
CG8945	NP_573190.1	M14_CP_A-B_like	1089..1430	CDD:199844	106/348 (30%)
CG3097	NP_572259.1	Propep_M14	64..118	CDD:280416	7/53 (13%)
CG3097	NP_572259.1	M14_CP_A-B_like	148..439	CDD:199844	106/348 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920