DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8945 and Cpb1

DIOPT Version :9

Sequence 1:	NP_573190.1	Gene:	CG8945 / 32693	FlyBaseID:	FBgn0030815	Length:	1430	Species:	Drosophila melanogaster
Sequence 2:	NP_036665.2	Gene:	Cpb1 / 24271	RGDID:	2391	Length:	415	Species:	Rattus norvegicus

Alignment Length:	465	Identity:	126/465 - (27%)
Similarity:	220/465 - (47%)	Gaps:	89/465 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   981 YDKYQIWRLKPQDEEQVRALEEFKKGEDGVKLQWLKGPS---LRGLT--DVLVPPKMLVDFQGTL 1040
            :|..:::|:....|:.|..::|....::   :.:.|..|   ::.||  |..|..:.:.|.:..|
  Rat    20 FDGNRVYRVSVHGEDHVNLIQELANTKE---IDFWKPDSATQVKPLTTVDFHVKAEDVADVENFL 81

  Fly  1041 NYEGIAHEVLIFDVGKAIAYELTKEDYLQTTRPSKPRPTAPPPMTWNRYHNHDEIVKYLETVRMR 1105
            ....:.:||||.:|..|:     :..:...||.|        ..::.:|:..:.|..:::.|...
  Rat    82 EENEVHYEVLISNVRNAL-----ESQFDSHTRAS--------GHSYTKYNKWETIEAWIQQVATD 133

  Fly  1106 HPQLVELIHIGRSFEGRPLIVVKIESKQTAAAANNDGLHTIKRPKRKRKSGQANAVFVEAGAQGL 1170
            :|.||....||.:||||.:.|:||..               .||.:.       |:|::.|....
  Rat   134 NPDLVTQSVIGTTFEGRNMYVLKIGK---------------TRPNKP-------AIFIDCGFHAR 176

  Fly  1171 AWIGPAAATWMIAELLRLMKTNKSNEDV---EFIRNTTWYIMPVLNPDGYAYSHEYDRFWKKSRS 1232
            .||.||...|.:.|.:|..     |:::   :.:....:|::||:|.|||.|:...||.|:|:||
  Rat   177 EWISPAFCQWFVREAVRTY-----NQEIHMKQLLDELDFYVLPVVNIDGYVYTWTKDRMWRKTRS 236

  Fly  1233 QHQTPPPSGLLDSAMTWLQQKRGPDKVCYGVDLDRNWLYHWGKRGSSKAPCNEFYAGPAPFSEPE 1297
            .        :..|:             |.|||.:||:...|.:.|:|::||:|.|.||||.||.|
  Rat   237 T--------MAGSS-------------CLGVDPNRNFNAGWCEVGASRSPCSETYCGPAPESEKE 280

  Fly  1298 TKAVSEFLMDYRTQIKLYISLQAYGQVISYPVKANSTF--NSERLDDFLDVAMVGTDGLRKK--- 1357
            |||:::|:.:..:.||.|:::.:|.|::.||...:...  |.|.|:     |:|  .|..|:
  Rat   281 TKALADFIRNNLSTIKAYLTIHSYSQMMLYPYSYDYKLPENYEELN-----ALV--KGAAKELAT 338

  Fly  1358 --GSKSRYKVDASNDLIEQRSGCADAFAAYEIGIPFSYTLQLADNGVHGYLLPSSAIEPTARDAF 1420
              |:|..|...|:.  |...:|.:|.: :|:.||.:|:|.:|.|.|..|:|||.|.|..|..:..
  Rat   339 LHGTKYTYGPGATT--IYPAAGGSDDW-SYDQGIKYSFTFELRDTGFFGFLLPESQIRQTCEETM 400

  Fly  1421 EIISGMLDYI 1430
            ..:..:.:|:
  Rat   401 LAVKYIANYV 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8945	NP_573190.1	Propep_M14	988..1058	CDD:280416	17/74 (23%)
CG8945	NP_573190.1	M14_CP_A-B_like	1089..1430	CDD:199844	103/350 (29%)
Cpb1	NP_036665.2	Propep_M14	33..102	CDD:396700	17/76 (22%)
Cpb1	NP_036665.2	M14_CPB	112..410	CDD:349443	103/355 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820