back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8945 and Cpa1

DIOPT Version :9

Sequence 1:	NP_573190.1	Gene:	CG8945 / 32693	FlyBaseID:	FBgn0030815	Length:	1430	Species:	Drosophila melanogaster
Sequence 2:	NP_058694.2	Gene:	Cpa1 / 24269	RGDID:	2388	Length:	419	Species:	Rattus norvegicus

Alignment Length:	456	Identity:	132/456 - (28%)
Similarity:	217/456 - (47%)	Gaps:	75/456 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   984 YQIWRLKPQDEEQVRALEEFKKGEDGVKLQWLKGPSLRGL-TDVLVPPKMLVDFQGTLNYEGIAH 1047
            :|:.|:...||.||:.::|.:..|. ::|.:.:..:..|: .||.||...:...:..|.|.||::
  Rat    23 HQVLRISAADEAQVQKVKELEDLEH-LQLDFWRDAARAGIPIDVRVPFPSIQSVKAFLEYHGISY 86

  Fly  1048 EVLIFDVGKAIAYELTKEDYLQTTRPSKPRPTAPPPMTWNRYHNHDEIVKYLETVRMRHPQLVEL 1112
            |::|.||      :|..::..|.....:.|..:.....:..||..|||.::::.:...|||||..
  Rat    87 EIMIEDV------QLLLDEEKQQMSAFQARALSTDSFNYATYHTLDEIYEFMDLLVAEHPQLVSK 145

  Fly  1113 IHIGRSFEGRPLIVVKIESKQTAAAANNDGLHTIKRPKRKRKSGQANAVFVEAGAQGLAWIGPAA 1177
            |.||.:|||||:.|:|..:..|            .||          |::::.|.....|:..|:
  Rat   146 IQIGNTFEGRPIHVLKFSTGGT------------NRP----------AIWIDTGIHSREWVTQAS 188

  Fly  1178 ATWMIAELLRLMKTNKSNEDVEF---IRNTTWYIMPVLNPDGYAYSHEYDRFWKKSRSQHQTPPP 1239
            ..|...::     |....:|..|   :.|...::..|.||||:||:|:.:|.|:|:||..|
  Rat   189 GVWFAKKI-----TKDYGQDPTFTAVLDNMDIFLEIVTNPDGFAYTHKTNRMWRKTRSHTQ---- 244

  Fly  1240 SGLLDSAMTWLQQKRGPDKVCYGVDLDRNWLYHWGKRGSSKAPCNEFYAGPAPFSEPETKAVSEF 1304
                             ..:|.|||.:|||...:|..|:|..||:|.|.|..|.||.|.|::.:|
  Rat   245 -----------------GSLCVGVDPNRNWDAGFGMAGASSNPCSETYRGKFPNSEVEVKSIVDF 292

  Fly  1305 LMDYRTQIKLYISLQAYGQVISYPVKANSTFNSE------RLDDFLDVAMVGTDGLRKKGSKSRY 1363
            :..: ..||.:||:.:|.|::.||.    .:.||      .||.....|:.....|.  |:|  :
  Rat   293 VTSH-GNIKAFISIHSYSQLLLYPY----GYTSEPAPDQAELDQLAKSAVTALTSLH--GTK--F 348

  Fly  1364 KVDASNDLIEQRSGCADAFAAYEIGIPFSYTLQLADNGVHGYLLPSSAIEPTARDAFEIISGMLD 1428
            |..:..|.|.|.||....: .|..||.:|:|.:|.|.|:.|:|||:|.|.|||.:.:..:..::|
  Rat   349 KYGSIIDTIYQASGSTIDW-TYSQGIKYSFTFELRDTGLRGFLLPASQIIPTAEETWLALLTIMD 412

  Fly  1429 Y 1429
            :
  Rat   413 H 413

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.