DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG8945 and CPB2

DIOPT Version :10

Sequence 1:NP_573190.1 Gene:CG8945 / 32693 FlyBaseID:FBgn0030815 Length:1430 Species:Drosophila melanogaster
Sequence 2:NP_001863.3 Gene:CPB2 / 1361 HGNCID:2300 Length:423 Species:Homo sapiens


Alignment Length:463 Identity:133/463 - (28%)
Similarity:215/463 - (46%) Gaps:89/463 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   980 SYDKYQIWRLKPQDEEQVRALEEFKKGEDGVKLQWLKGPSLRGLTDVLVPPKMLVDF-------- 1036
            ::...|:....|:...||:.|:......:.|..|.:       ..|::|..|.:..|        
Human    22 AFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPV-------TADLIVKKKQVHFFVNASDVDN 79

  Fly  1037 -QGTLNYEGIAHEVLIFDVGKAIAYELTKEDYLQTTRPSKPRPTAPPPMTWNRYHNHDEIVKYLE 1100
             :..||..||...||:.||...|..:::.:..       .||.:|   ..:.:||:.:||..::|
Human    80 VKAHLNVSGIPCSVLLADVEDLIQQQISNDTV-------SPRASA---SYYEQYHSLNEIYSWIE 134

  Fly  1101 TVRMRHPQLVELIHIGRSFEGRPLIVVKIESKQTAAAANNDGLHTIKRPKRKRKSGQANAVFVEA 1165
            .:..|||.::..||||.|||..||.|:|:..|:.||                     .||::::.
Human   135 FITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAA---------------------KNAIWIDC 178

  Fly  1166 GAQGLAWIGPAAATWMIAELLRL-----MKTNKSNEDVEFIRNTTWYIMPVLNPDGYAYSHEYDR 1225
            |.....||.||...|.|..:.:.     ..||       .:|...:|:|||:|.|||.||.:.:|
Human   179 GIHAREWISPAFCLWFIGHITQFYGIIGQYTN-------LLRLVDFYVMPVVNVDGYDYSWKKNR 236

  Fly  1226 FWKKSRSQHQTPPPSGLLDSAMTWLQQKRGPDKVCYGVDLDRNWL-YHWGKRGSSKAPCNEFYAG 1289
            .|:|:||.:                     .:..|.|.||:||:. .||.:.|:|.:.|:|.|.|
Human   237 MWRKNRSFY---------------------ANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCG 280

  Fly  1290 PAPFSEPETKAVSEFLMDYRTQIKLYISLQAYGQVISYPVKANSTFNSERLDDFLDVAMVGTDGL 1354
            ..|.||||.|||:.||.....|||.|||:.:|.|.|.:|.    ::...:..|..::::|.::.:
Human   281 LYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPY----SYTRSKSKDHEELSLVASEAV 341

  Fly  1355 R---KKGSKSRYKVDASNDLIEQRSGCADAFAAYEIGIPFSYTLQLADNGVHGYLLPSSAIEPTA 1416
            |   |....:||.....::.:....|..|.: .|::||.:|:|::|.|.|.:|:|||...|:||.
Human   342 RAIEKISKNTRYTHGHGSETLYLAPGGGDDW-IYDLGIKYSFTIELRDTGTYGFLLPERYIKPTC 405

  Fly  1417 RDAFEIIS 1424
            |:||..:|
Human   406 REAFAAVS 413

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8945NP_573190.1 PHA03175 396..>525 CDD:177551
Propep_M14 987..1061 CDD:460505 19/82 (23%)
Peptidase_M14 1095..1421 CDD:459730 105/334 (31%)
CPB2NP_001863.3 Propep_M14 33..105 CDD:460505 19/78 (24%)
M14_CPB2 119..420 CDD:349465 110/349 (32%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.