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Protein Alignment CG8945 and CPB1

DIOPT Version :9

Sequence 1:	NP_573190.1	Gene:	CG8945 / 32693	FlyBaseID:	FBgn0030815	Length:	1430	Species:	Drosophila melanogaster
Sequence 2:	NP_001862.2	Gene:	CPB1 / 1360	HGNCID:	2299	Length:	417	Species:	Homo sapiens

Alignment Length:	468	Identity:	117/468 - (25%)
Similarity:	207/468 - (44%)	Gaps:	95/468 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   981 YDKYQIWRLKPQDEEQVRALEEFKKGEDGVKLQWLKGPSLRGLTDVLVPPKMLVDF--------- 1036
            ::..:::|:..:||..:..:.|.   ....::.:.|..|:     ..:.|...|||
Human    22 FEGEKVFRVNVEDENHINIIREL---ASTTQIDFWKPDSV-----TQIKPHSTVDFRVKAEDTVT 78

  Fly  1037 -QGTLNYEGIAHEVLIFDVGKAIAYELTKEDYLQTTRPSKPRPTAPPPMTWNRYHNHDEIVKYLE 1100
             :..|....:.::|||.::...:..:.          .|:.|.|.   .::.:|:..:.|..:.:
Human    79 VENVLKQNELQYKVLISNLRNVVEAQF----------DSRVRATG---HSYEKYNKWETIEAWTQ 130

  Fly  1101 TVRMRHPQLVELIHIGRSFEGRPLIVVKIESKQTAAAANNDGLHTIKRPKRKRKSGQAN-AVFVE 1164
            .|...:|.|:....||.:||||.:.::|:                       .|:||.. |:|::
Human   131 QVATENPALISRSVIGTTFEGRAIYLLKV-----------------------GKAGQNKPAIFMD 172

  Fly  1165 AGAQGLAWIGPAAATWMIAELLRLMKTNKSNEDVEFIRNTTWYIMPVLNPDGYAYSHEYDRFWKK 1229
            .|.....||.||...|.:.|.:|..  .:..:..|.:....:|::||||.|||.|:....|||:|
Human   173 CGFHAREWISPAFCQWFVREAVRTY--GREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRK 235

  Fly  1230 SRSQHQTPPPSGLLDSAMTWLQQKRGPDKVCYGVDLDRNWLYHWGKRGSSKAPCNEFYAGPAPFS 1294
            :||.|                     ....|.|.|.:||:...|.:.|:|:.||:|.|.|||..|
Human   236 TRSTH---------------------TGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAES 279

  Fly  1295 EPETKAVSEFLMDYRTQIKLYISLQAYGQVISYPV-------KANSTFNSERLDDFLDVAMVGTD 1352
            |.||||:::|:.:..:.||.|:::.:|.|::.||.       :.|:..|:.......::|.:
Human   280 EKETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASL--- 341

  Fly  1353 GLRKKGSKSRYKVDASNDLIEQRSGCADAFAAYEIGIPFSYTLQLADNGVHGYLLPSSAIEPTAR 1417
                .|:|..|...|:.  |...:|.:|.: ||:.||.:|:|.:|.|.|.:|:|||.|.|..|..
Human   342 ----HGTKYTYGPGATT--IYPAAGGSDDW-AYDQGIRYSFTFELRDTGRYGFLLPESQIRATCE 399

  Fly  1418 DAFEIISGMLDYI 1430
            :.|..|..:..|:
Human   400 ETFLAIKYVASYV 412

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.