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Protein Alignment CG8945 and CPA1

DIOPT Version :9

Sequence 1:	NP_573190.1	Gene:	CG8945 / 32693	FlyBaseID:	FBgn0030815	Length:	1430	Species:	Drosophila melanogaster
Sequence 2:	NP_001859.1	Gene:	CPA1 / 1357	HGNCID:	2296	Length:	419	Species:	Homo sapiens

Alignment Length:	454	Identity:	130/454 - (28%)
Similarity:	217/454 - (47%)	Gaps:	71/454 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   984 YQIWRLKPQDEEQVRALEEFKKGEDGVKLQWLKGPSLRGL-TDVLVPPKMLVDFQGTLNYEGIAH 1047
            :|:.|:...||.||:.::|.:..|. ::|.:.:||:..|. .||.||...:...:..|...||::
Human    23 HQVLRISVADEAQVQKVKELEDLEH-LQLDFWRGPAHPGSPIDVRVPFPSIQAVKIFLESHGISY 86

  Fly  1048 EVLIFDVGKAIAYELTKEDYLQTTRPSKPRPTAPPPMTWN--RYHNHDEIVKYLETVRMRHPQLV 1110
            |.:|.||...:..|   ::.:...| |:.|.|.    |:|  .||..:||..:|:.:...:|.||
Human    87 ETMIEDVQSLLDEE---QEQMFAFR-SRARSTD----TFNYATYHTLEEIYDFLDLLVAENPHLV 143

  Fly  1111 ELIHIGRSFEGRPLIVVKIESKQTAAAANNDGLHTIKRPKRKRKSGQANAVFVEAGAQGLAWIGP 1175
            ..|.||.::||||:.|:|..:..:            |||          |::::.|.....|:..
Human   144 SKIQIGNTYEGRPIYVLKFSTGGS------------KRP----------AIWIDTGIHSREWVTQ 186

  Fly  1176 AAATWMIAELLRLMKTNKSNEDVEF---IRNTTWYIMPVLNPDGYAYSHEYDRFWKKSRSQHQTP 1237
            |:..|...::     |....:|..|   :.....::..|.||||:|::|..:|.|:|:||.
Human   187 ASGVWFAKKI-----TQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSH---- 242

  Fly  1238 PPSGLLDSAMTWLQQKRGPDKVCYGVDLDRNWLYHWGKRGSSKAPCNEFYAGPAPFSEPETKAVS 1302
             .:|.|                |.|||.:|||...:|..|:|..||:|.|.|....||.|.|::.
Human   243 -TAGSL----------------CIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIV 290

  Fly  1303 EFLMDYRTQIKLYISLQAYGQVISYP--VKANSTFNSERLDDFLDVAMVGTDGLRKKGSKSRYKV 1365
            :|:.|: ..||.:||:.:|.|::.||  .|.....:.:.||.....|:.....|  .|:|..|
Human   291 DFVKDH-GNIKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASL--YGTKFNY-- 350

  Fly  1366 DASNDLIEQRSGCADAFAAYEIGIPFSYTLQLADNGVHGYLLPSSAIEPTARDAFEIISGMLDY 1429
            .:....|.|.||....: .|..||.:|:|.:|.|.|.:|:|||:|.|.|||::.:..:..::::
Human   351 GSIIKAIYQASGSTIDW-TYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEH 413

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.