DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8945 and Cpa1

DIOPT Version :10

Sequence 1:NP_573190.1 Gene:CG8945 / 32693 FlyBaseID:FBgn0030815 Length:1430 Species:Drosophila melanogaster
Sequence 2:NP_079626.2 Gene:Cpa1 / 109697 MGIID:88478 Length:419 Species:Mus musculus


Alignment Length:452 Identity:130/452 - (28%)
Similarity:213/452 - (47%) Gaps:67/452 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   984 YQIWRLKPQDEEQVRALEEFKKGEDGVKLQWLKGPSLRGL-TDVLVPPKMLVDFQGTLNYEGIAH 1047
            :|:.|:...||.||:.:.|.::.|. :||.:.:.|:..|| .||.||...:...:..|.|..|::
Mouse    23 HQVLRISATDEAQVQKVRELEELEH-LKLDFWRDPARAGLPIDVRVPFPTIQSVKAFLEYHDISY 86

  Fly  1048 EVLIFDVGKAIAYELTKEDYLQTTRPSKPRPTAPPPMTWNRYHNHDEIVKYLETVRMRHPQLVEL 1112
            |::|.||...:..|..:....|.      |..:.....:..||..|||.::::.:...|||||..
Mouse    87 EIMIEDVQSLLDEEKQQMSAFQA------RALSTDAFNYATYHTLDEIYEFMDLLVTEHPQLVSK 145

  Fly  1113 IHIGRSFEGRPLIVVKIESKQTAAAANNDGLHTIKRPKRKRKSGQANAVFVEAGAQGLAWIGPAA 1177
            |.||.:|||||:.|:|..:..|            .||          |::::.|.....|:..|:
Mouse   146 IQIGSTFEGRPINVLKFSTGGT------------NRP----------AIWIDTGIHSREWVTQAS 188

  Fly  1178 ATWMIAELLRLMKTNKSNED---VEFIRNTTWYIMPVLNPDGYAYSHEYDRFWKKSRSQHQTPPP 1239
            ..|...::     |....::   ...:.|...::..|.||||:.|:|:.:|.|:|:||..:    
Mouse   189 GVWFAKKI-----TKDYGQEPTLTAILDNMDIFLEIVTNPDGFVYTHKTNRMWRKTRSHTE---- 244

  Fly  1240 SGLLDSAMTWLQQKRGPDKVCYGVDLDRNWLYHWGKRGSSKAPCNEFYAGPAPFSEPETKAVSEF 1304
                             ..:|.|||.:|||...:|..|:|..||:|.|.|..|.||.|.|::.:|
Mouse   245 -----------------GSLCVGVDPNRNWDAAFGMPGASSNPCSETYRGKFPNSEVEVKSIVDF 292

  Fly  1305 LMDYRTQIKLYISLQAYGQVISYPVKANS--TFNSERLDDFLDVAMVGTDGLRKKGSKSRYKVDA 1367
            :..: ..||.:||:.:|.|::.||....|  ..:.|.||.....|:.....|.  |:|  :|..:
Mouse   293 VTSH-GNIKAFISIHSYSQLLLYPYGYTSEPAPDKEELDQLAKSAVTALTSLH--GTK--FKYGS 352

  Fly  1368 SNDLIEQRSGCADAFAAYEIGIPFSYTLQLADNGVHGYLLPSSAIEPTARDAFEIISGMLDY 1429
            ..|.|.|.||....: .|..||.:|:|.:|.|.|:.|:|||:|.|.|||.:.:..:..::|:
Mouse   353 IIDTIYQASGSTIDW-TYSQGIKYSFTFELRDTGLRGFLLPASQIIPTAEETWLALLTIMDH 413

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8945NP_573190.1 PHA03175 396..>525 CDD:177551
Propep_M14 987..1061 CDD:460505 23/74 (31%)
Peptidase_M14 1095..1421 CDD:459730 98/330 (30%)
Cpa1NP_079626.2 Propep_M14 26..100 CDD:460505 23/74 (31%)
M14_CPA 117..417 CDD:349442 103/351 (29%)
Blue background indicates that the domain is not in the aligned region.

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