DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8945 and cpo.2

DIOPT Version :9

Sequence 1:	NP_573190.1	Gene:	CG8945 / 32693	FlyBaseID:	FBgn0030815	Length:	1430	Species:	Drosophila melanogaster
Sequence 2:	XP_002937157.1	Gene:	cpo.2 / 100487462	XenbaseID:	XB-GENE-22169695	Length:	454	Species:	Xenopus tropicalis

Alignment Length:	468	Identity:	122/468 - (26%)
Similarity:	214/468 - (45%)	Gaps:	85/468 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   979 ISYDKYQIWRLKPQDEEQVRALEEFKKGEDGVKLQWL-------------KGPSLRGLTDVLVPP 1030
            :.|:...::::.|:..|..:.|:....       :||             :|..:.    |.:|.
Frog    23 VQYNGDNVFKITPETSEHAQYLQTLAN-------EWLLDLWRPQTVEQIHEGSDIH----VQIPF 76

  Fly  1031 KMLVDFQGTLNYEGIAHEVLIFDVGKAIAYELTKEDYLQTTRPSKPRPTAPPPMTWNRYHNHDEI 1095
            ..:...:..|....|.:||||.||.|.|.        ..|....|.:..:.....:.:||..|||
Frog    77 AYMEQMKQKLLQHSIPYEVLINDVQKLID--------SNTVSAPKIQKASLENYDYTKYHPMDEI 133

  Fly  1096 VKYLETVRMRHPQLVELIHIGRSFEGRPLIVVKIESKQTAAAANNDGLHTIKRPKRKRKSGQANA 1160
            ..:::.::.:|.::|...:||.::|.||:..:|                 |..|..|:|    ..
Frog   134 YNWMDLMKEKHSEIVSQHYIGCTYELRPMYYLK-----------------IGWPSDKQK----KI 177

  Fly  1161 VFVEAGAQGLAWIGPAAATWMIAELLRLMKTNKSNEDVEFIRNTTWYIMPVLNPDGYAYSHEYDR 1225
            .|::.|.....||..|...|.:.|::...||:....:|  ::...:|::||:|.|||.|:...:|
Frog   178 FFIDCGFHAREWISVAFCQWFVNEIVSHYKTDAILANV--LKQVDFYVLPVMNIDGYVYTWTTNR 240

  Fly  1226 FWKKSRSQHQTPPPSGLLDSAMTWLQQKRGPDKVCYGVDLDRNWLYHWGKRGSSKAPCN-EFYAG 1289
            .|:|:||.|:                     :..||||||:||:...|...|:|: .|| ..:.|
Frog   241 LWRKNRSPHE---------------------NGTCYGVDLNRNFDSQWCSIGASR-DCNSNTFCG 283

  Fly  1290 PAPFSEPETKAVSEFLMDYRTQIKLYISLQAYGQVI--SYPVKANSTFNSERLDDFLDVAMVGTD 1352
            |...|||||||:|..:...::.|..|:::.:|||:|  .|..|.:.:.|.   |:.:.||.....
Frog   284 PEAASEPETKALSGLIEKTKSDILCYLTIHSYGQMILLPYGYKKDPSPNH---DEMMLVAKNAVA 345

  Fly  1353 GLRKKGSKSRYKVDASNDLIEQRSGCADAFAAYEIGIPFSYTLQLADNGVHGYLLPSSAIEPTAR 1417
            .:::| ..:.|:.::|..::...||.:..:.. |:||..||||:|.|||.:|::||...|:||..
Frog   346 KMKEK-HNNEYEYESSAVILYYDSGSSGDWTV-ELGIQLSYTLELRDNGTYGFVLPPDQIKPTCE 408

  Fly  1418 DAFEIISGMLDYI 1430
            :....:..|::||
Frog   409 ETTTAVMSMVEYI 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8945	NP_573190.1	Propep_M14	988..1058	CDD:280416	17/82 (21%)
CG8945	NP_573190.1	M14_CP_A-B_like	1089..1430	CDD:199844	99/343 (29%)
cpo.2	XP_002937157.1	Propep_M14	36..105	CDD:366995	16/79 (20%)
cpo.2	XP_002937157.1	M14_CPO	124..421	CDD:349466	99/346 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020