DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8945 and cpo

DIOPT Version :9

Sequence 1:	NP_573190.1	Gene:	CG8945 / 32693	FlyBaseID:	FBgn0030815	Length:	1430	Species:	Drosophila melanogaster
Sequence 2:	NP_001139101.1	Gene:	cpo / 100005630	ZFINID:	ZDB-GENE-070619-6	Length:	363	Species:	Danio rerio

Alignment Length:	348	Identity:	106/348 - (30%)
Similarity:	179/348 - (51%)	Gaps:	50/348 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly  1086 WNRYHNHDEIVKYLETVRMRHPQLVELIHIGRSFEGRPLIVVKIESKQTAAAANNDGLHTIKRPK 1150
            :.:||..|||..::..::..:|.:|..:..|:::|.|.:.::||....|.             ||
Zfish    32 YTKYHTMDEISAWMNQMQRENPDVVSTMTYGQTYEKRNITLLKIGFSSTT-------------PK 83

  Fly  1151 RKRKSGQANAVFVEAGAQGLAWIGPAAATWMIAELLRLMKTNKSNEDVEFIRNTTWYIMPVLNPD 1215
            :        |::::.|.....||.||.....:.|:|...||: |..::.| :|..:||.||||.|
Zfish    84 K--------AIWMDCGIHAREWIAPAFCQHFVKEVLGSYKTD-SRVNMLF-KNLDFYITPVLNMD 138

  Fly  1216 GYAYS--HEYDRFWKKSRSQ-HQTPPPSGLLDSAMTWLQQKRGPDKVCYGVDLDRNWLYHWGKRG 1277
            ||.||  :...|.|:||||. |:                     :..|.|.||:||:..:||..|
Zfish   139 GYIYSWLNNSTRLWRKSRSPCHE---------------------NSTCSGTDLNRNFYANWGMVG 182

  Fly  1278 SSKAPCNEFYAGPAPFSEPETKAVSEFLMDYRTQIKLYISLQAYGQVISYPVKANSTFNSERLDD 1342
            .|:..|:|.|.|....||||.:||::||..::..:..|:::.:|||:|..|. .:...::...|:
Zfish   183 ISRNCCSEVYNGATALSEPEAEAVTDFLGAHQNHLLCYLTIHSYGQLILVPY-GHPNISAPNYDE 246

  Fly  1343 FLDVAMVGTDGLRKKGSKSRYKVDASNDLIEQRSGCADAFAAYEIGIPFSYTLQLADNGVHGYLL 1407
            .::|.:.....::....|| |||.:|.|::...||.:..||.. ||||:|:|.:|.|.|.||::|
Zfish   247 LMEVGLAAAKAIKAVHGKS-YKVGSSPDVLYPNSGSSRDFARL-IGIPYSFTFELRDEGQHGFIL 309

  Fly  1408 PSSAIEPTARDAFEIISGMLDYI 1430
            |...|:||.::|:|....:::|:
Zfish   310 PEDQIQPTCQEAYEGAMSIINYV 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8945	NP_573190.1	Propep_M14	988..1058	CDD:280416
CG8945	NP_573190.1	M14_CP_A-B_like	1089..1430	CDD:199844	105/343 (31%)
cpo	NP_001139101.1	M14_CP_A-B_like	35..332	CDD:199844	105/343 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.920