Protein Alignment CG45002 and DAP2

DIOPT Version :10

• Sequence 1: NP_728041.3
• Gene: CG45002 / 32688
• FlyBaseID: FBgn0266354
• Length: 1098
• Species: Drosophila melanogaster
• Sequence 2: NP_011893.1
• Gene: DAP2 / 856423
• SGDID: S000001070
• Length: 818
• Species: Saccharomyces cerevisiae
• Alignment Length: 980
• Identity: 224/980 - (22%)
• Similarity: 367/980 - (37%)
• Gaps: 275/980 - (28%)

  Fly    54 GIFIALLVIAAVFSL--------------------------IIFSIFLLSPEDEGLRIRGRRMLP 92
            ||.:.||:...|..|                          :.||:           :|.....|
Yeast    31 GIILVLLIWGTVLLLKSIPHHSNTPDYQEPNSNYTNDGKLKVSFSV-----------VRNNTFQP 84

  Fly    93 SDILGRSLQWKPFNGTWSNGRELIYRDPTGGLSILNMA--------DLTTRILMTNSTF----RQ 145
            .   ...|||...|...||...|.       ::.:|.:        |....:|:...||    :.
Yeast    85 K---YHELQWISDNKIESNDLGLY-------VTFMNDSYVVKSVYDDSYNSVLLEGKTFIHNGQN 139

  Fly   146 LNAESFLVAPDQKYVLLQSDSNAEGSRH------HVYEVQTANTFPLGPTENIAEAPRLQHVVWA 204
            |..||...:||.|.:|::::| .:..||      .||:..:::...:|....:|        :|:
Yeast   140 LTVESITASPDLKRLLIRTNS-VQNWRHSTFGSYFVYDKSSSSFEEIGNEVALA--------IWS 195

  Fly   205 PANPPPPLGAPPPSGASGASGASGASTTTMAPLPSGSIILNSLAGAANGPASAGASGSSAPNPNG 269
            |
Yeast   196 P---------------------------------------------------------------- 196

  Fly   270 KAGGYNLNQAIAFVHHNDIYYKPKVQGELVCRITQTGSGSLEGESTGVVFNGVPDWMYENVPELE 334
                 |.|. ||:|..|:||....:..:.:..:|..||..|        |||.|||:||.  |:.
Yeast   197 -----NSND-IAYVQDNNIYIYSAISKKTIRAVTNDGSSFL--------FNGKPDWVYEE--EVF 245

  Fly   335 SRRSSMEFSPDGLFLAFLSYNDSEVNEYKYTWMGDDIK--YPAVMSQRYPKTGSRNPNVTVNVVN 397
            ....:..:||.|.:||||..::|||.|:...:...|.|  ||.:.|.:|||:|:.||:..:.|.:
Yeast   246 EDDKAAWWSPTGDYLAFLKIDESEVGEFIIPYYVQDEKDIYPEMRSIKYPKSGTPNPHAELWVYS 310

  Fly   398 LSVIKYIFPTQIKLPSELSNGS-YVGGLTWASSTDLSVTVTNREQTKATTVLCRAPHFHCQAVHT 461
            :.......|   ::.....:|| .:..:||..:.::.|..|:|.....|..|..........|..
Yeast   311 MKDGTSFHP---RISGNKKDGSLLITEVTWVGNGNVLVKTTDRSSDILTVFLIDTIAKTSNVVRN 372

  Fly   462 EVTINDGWVLPSERPIFSVRNQGHNRLGKMVQNAEEIQAESQNVNVTDGQTHTTHEISNGGYLLK 526
            | :.|.||...:...:|...|:                               |.:..:.|| :.
Yeast   373 E-SSNGGWWEITHNTLFIPANE-------------------------------TFDRPHNGY-VD 404

  Fly   527 RLPVRDGEHGHYRHVV-FISSLDRRPVPLTMGRFEVTE-IVGWDEPHEIVYFMAAPEKRPGERHL 589
            .||:     |.|.|:. |.:|.......||.|::||.. .:.:|.....:||::. .|...|||:
Yeast   405 ILPI-----GGYNHLAYFENSNSSHYKTLTEGKWEVVNGPLAFDSMENRLYFIST-RKSSTERHV 463

  Fly   590 YKISLKLNVTESNRTYITSTSPTCLTCDNTESTYRLHRARISQRGDRWEDIVARLEPDDCLYDIP 654
            |.|.|:   :.:....:|.||                                    :|.:||
Yeast   464 YYIDLR---SPNEIIEVTDTS------------------------------------EDGVYD-- 487

  Fly   655 KNCLFNRVQFSQDYSYYVQECLGPEAPSVYLVETASN-----DK-------IYVLNAGDVLRHRL 707
                   |.||....:.:....||:.|...:|:..|.     ||       :|.|...:||...|
Yeast   488 -------VSFSSGRRFGLLTYKGPKVPYQKIVDFHSRKAEKCDKGNVLGKSLYHLEKNEVLTKIL 545

  Fly   708 SQLAIPQSRTFSVEIRHG---FHAQVRL----FLPPGMREEEDVAFPLVLHVDASPGSQLVTERF 765
            ...|:|: ::|. |:..|   |...:.:    .||....|.....:|:.......|.||.|.:.|
Yeast   546 EDYAVPR-KSFR-ELNLGKDEFGKDILVNSYEILPNDFDETLSDHYPVFFFAYGGPNSQQVVKTF 608

  Fly   766 HVDWNWYLASQRSFIVAQIDGRGSGFQGELLRTQVHGKLGTVEVEDQLGVLTYLRDNLKFIDPLR 830
            .|.:|..:|||.:.||..:||||:||:|:..|:.|..:||..|..||:...: |..:|.|:||.:
Yeast   609 SVGFNEVVASQLNAIVVVVDGRGTGFKGQDFRSLVRDRLGDYEARDQISAAS-LYGSLTFVDPQK 672

  Fly   831 ICAFGWGYGGYASSMMLIDDSQQVLQCAVAINPIVNFGFHYSFFTERYIPLKGDYLRALQEADLT 895
            |..|||.||||.:...|..|..:..:..:::.|:.::.|:.|.:||||:....:......|:.:.
Yeast   673 ISLFGWSYGGYLTLKTLEKDGGRHFKYGMSVAPVTDWRFYDSVYTERYMHTPQENFDGYVESSVH 737

  Fly   896 MKAGNIKGRNLMLMHGTADTLVHQEHTLMLVRALVEQQVK-FRHQVYPDEDHAIARSLSHVY--- 956
            ......:....:|||||.|..||.:::|..:..|....|: :...|:||.||:|....::|.
Yeast   738 NVTALAQANRFLLMHGTGDDNVHFQNSLKFLDLLDLNGVENYDVHVFPDSDHSIRYHNANVIVFD 802

  Fly   957 KTMEW 961
            |.::|
Yeast   803 KLLDW 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45002	NP_728041.3	DPPIV_N	278..681	CDD:395744	95/407 (23%)
		Peptidase_S9	765..969	CDD:459761	65/201 (32%)
DAP2	NP_011893.1	DPPIV_N	148..508	CDD:395744	110/538 (20%)
		Peptidase_S9	608..815	CDD:459761	65/201 (32%)