Protein Alignment CG45002 and dpp4

DIOPT Version :10

• Sequence 1: NP_728041.3
• Gene: CG45002 / 32688
• FlyBaseID: FBgn0266354
• Length: 1098
• Species: Drosophila melanogaster
• Sequence 2: XP_012825865.2
• Gene: dpp4 / 548987
• XenbaseID: XB-GENE-976654
• Length: 810
• Species: Xenopus tropicalis
• Alignment Length: 945
• Identity: 245/945 - (25%)
• Similarity: 408/945 - (43%)
• Gaps: 215/945 - (22%)

  Fly    45 ISPERRNWRGIFIALLVIAAVFSLIIFSIFLLSPEDEGLRIRGRRMLPSDILGRSLQWKPFNGTW 109
            |..:.:.|....:.:|:.|.|.:::...:.||:  .:|.....:.....|..|...:.|.|...|
 Frog    56 IPRKMKTWLKWLLGILMGAVVVTVVAVPVALLA--TKGKEDTRKTFTLEDYFGDEYRAKSFGLKW 118

  Fly   110 SNGRELIYRDPTGGLSILNMADLTTRILMTNSTFRQLNAESFLVAPDQKYVLLQSD-----SNAE 169
            .:..|.::|.....| |.|:.:..|..:::|:|....|:..:.::.::.|.|||.:     .::.
 Frog   119 VSENEFLFRTKDNVL-IYNVDNEKTTEMISNTTIYNSNSSFYTLSDNRNYALLQYNYEKLWRHSY 182

  Fly   170 GSRHHVY-----EVQTANTFPLGPTENIAEAPRLQHVVWAPANPPPPLGAPPPSGASGASGASGA 229
            .:.:|:|     |:.|||..|          .::|::.|:|
 Frog   183 TASYHIYDTVKGEIVTANVLP----------NQIQYITWSP------------------------ 213

  Fly   230 STTTMAPLPSGSIILNSLAGAANGPASAGASGSSAPNPNGKAGGYNLNQAIAFVHHNDIYYKPKV 294
                                                          :...:|:|..|:||.|...
 Frog   214 ----------------------------------------------VGNKLAYVWENNIYIKETP 232

  Fly   295 QGELVCRITQTGSGSLEGESTGVVFNGVPDWMYENVPELESRRSSMEFSPDGLFLAFLSYNDSEV 359
            .|..: :||..|..:       .:.||:|||:||.  |:.|...::.:|||...||::.:||::|
 Frog   233 GGSSI-QITTNGEHN-------KILNGIPDWVYEE--EMFSTNYALWWSPDAASLAYVEFNDTDV 287

  Fly   360 NEYKYTWMGDDI-KYPAVMSQRYPKTGSRNPNVTVNVVNLSVIKYIFPTQIKLPSELSN-GSYVG 422
            ...:|::.|:|. :||..:...|||.|::||.|.:.|||.:.:......:|..|:||.. ..|:.
 Frog   288 PAIEYSFYGEDSDQYPKTVVIPYPKAGAKNPTVRLFVVNTASLPAFNSVEIPPPAELRTIDYYIN 352

  Fly   423 GLTWASSTDLSVTVTNREQTKATTVLC--RAPHFHCQ-AVHTEVTINDGWV---LPSERPIFSVR 481
            |:.|.::..::|....|.|..:...:|  .||.::|| .|:.:.|  .|||   .||. |.|:
 Frog   353 GMNWVTNGKMAVQWLRRIQNVSLLTVCDFAAPAWNCQPPVYEQST--TGWVGYFQPSS-PYFT-- 412

  Fly   482 NQGHNRLGKMVQNAEEIQAESQNVNVTDGQTHTTHEISNGGYLLKRLPVRDGEHGHYRHVVFISS 546
             |...:..|::.|.|                                        .::|:.....
 Frog   413 -QDGQKYYKVISNKE----------------------------------------GFKHIHLFEG 436

  Fly   547 LDRRPVPLTMGRFEVTEIVGWDEPHEIVYFMAAPEKRPGERHLYKISLKLNVTESNRTYITSTSP 611
            . :.||.:|.|::|||.|.  .....::|:: :.|..||.|.||||.|...          |.|.
 Frog   437 A-KEPVAITSGKWEVTSIT--TVASNLLYYI-SNEGFPGRRQLYKIRLDGG----------SNSA 487

  Fly   612 TCLTCDNTESTYRLHRARISQRGDRWEDIVARLEPDDCLYDIPKNCLFNRVQFSQDYSYYVQECL 676
            .|:||:            |.|                      :.|......||:|..||...|.
 Frog   488 QCVTCN------------IRQ----------------------ERCQQYSAYFSKDSKYYALNCN 518

  Fly   677 GPEAPSVYLVETASNDK-IYVLNAGDVLRHRLSQLAIPQSRTFSVEIRHGFHAQVRLFLPPGMRE 740
            ||..| :|.:..:|||| ::::...:.|:..|.::.:|.....|: |..||....:|.|||..
 Frog   519 GPGVP-IYTLYNSSNDKEMHIMEDNEELKLLLDEVQMPTKENKSI-IIDGFELWYQLTLPPNF-- 579

  Fly   741 EEDVAFPLVLHVDASPGSQLVTERFHVDWNWYLASQRSFIVAQIDGRGSGFQGELLRTQVHGKLG 805
            ::...:||::.|...|.||.|.:.|.::|..||||....|||..||||||:||:.:..|::.|||
 Frog   580 DKSKKYPLLIDVYGGPCSQKVDQYFRLNWATYLASTEKIIVASFDGRGSGYQGDKIMHQLYHKLG 644

  Fly   806 TVEVEDQLGVLTYLRDNLKFIDPLRICAFGWGYGGYASSMMLIDDSQQVLQCAVAINPIVNFGFH 870
            |:||:||:....|. ..|.|:||.||..:||.||||.:||:| .....:.:|.:|:.|:.::.::
 Frog   645 TLEVQDQIAAARYF-ITLGFVDPKRIAIWGWSYGGYVTSMVL-GSGSGLFKCGIAVAPVSSWEYY 707

  Fly   871 YSFFTERY--IPLKGDYLRALQEADLTMKAGNIKGRNLMLMHGTADTLVHQEHTLMLVRALVEQQ 933
            .|.:||||  :|...|.|.....:.:..:|...|....:|:|||||..||.:....:.:|||:.|
 Frog   708 DSIYTERYMGLPTPEDNLENYLSSTVMARAQKFKDVEYLLIHGTADDNVHFQQAAHISKALVDAQ 772

  Fly   934 VKFRHQVYPDEDHAIARSLS-HVYKTMEWYFDECF 967
            |.|....|.|:||.|..:.: |:|..|..|..:||
 Frog   773 VDFDTMWYTDKDHGIGGTANRHIYTHMSHYLKQCF 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45002	NP_728041.3	DPPIV_N	278..681	CDD:395744	105/410 (26%)
		Peptidase_S9	765..969	CDD:459761	80/206 (39%)
dpp4	XP_012825865.2	DPPIV_rep	94..114	CDD:465875	3/19 (16%)
		DPPIV_N	162..524	CDD:395744	120/546 (22%)
		Peptidase_S9	604..810	CDD:459761	80/206 (39%)