Protein Alignment CG45002 and Dpp10

DIOPT Version :10

• Sequence 1: NP_728041.3
• Gene: CG45002 / 32688
• FlyBaseID: FBgn0266354
• Length: 1098
• Species: Drosophila melanogaster
• Sequence 2: NP_001402045.1
• Gene: Dpp10 / 363972
• RGDID: 1306427
• Length: 800
• Species: Rattus norvegicus
• Alignment Length: 974
• Identity: 271/974 - (27%)
• Similarity: 420/974 - (43%)
• Gaps: 214/974 - (21%)

  Fly    15 SLKRETVVVNNSAPTIKKVTLVPKDEELVAISPERRNWRGIFIALLVIAAVFSLIIFSIFLLSPE 79
            ::|:|    ....|..:.....|.|:||.:.||.:|||:||.||||||..|.|||..|:.||:|
  Rat     3 AMKQE----QQPTPGARATQSQPADQELGSNSPPQRNWKGIAIALLVILVVCSLITMSVILLTP- 62

  Fly    80 DEGLRIRGRRMLPSDILGRSLQWKPFNGTWSNGRELIYRDPTGGLSILNMADLTTRILMTNSTFR 144
            ||.......|:...::||:..........|.|..:::|:...|.:..||.....|.:|:.||||.
  Rat    63 DELTNSSETRLSLEELLGKGFGLHNPEARWINDTDVVYKTDNGHVMKLNAETNATTLLLDNSTFV 127

  Fly   145 QLNAESFLVAPDQKYVLLQSDSN-----AEGSRHHVYEVQTANTFPLGPTENIAEAPRLQHVVWA 204
            ...|....::||.|||||..|..     :..:.:.:|.:.|...:.|.|.|  .|...||:..|
  Rat   128 TFKASRHSLSPDLKYVLLAYDVKQIFHYSFTASYLIYNIHTGEVWELNPPE--VEDSVLQYAAW- 189

  Fly   205 PANPPPPLGAPPPSGASGASGASGASTTTMAPLPSGSIILNSLAGAANGPASAGASGSSAPNPNG 269
                                                                 |..|
  Rat   190 -----------------------------------------------------GVQG-------- 193

  Fly   270 KAGGYNLNQAIAFVHHNDIYYKPKVQGELVCRITQTGSGSLEGESTGVVFNGVPDWMYENVPELE 334
                    |.:.::..|:|||:|.::...: |:|.:|       ..|:||||:.||:||.  ||.
  Rat   194 --------QQLIYIFENNIYYQPDIKSSSL-RLTSSG-------KEGIVFNGIADWLYEE--ELL 240

  Fly   335 SRRSSMEFSPDGLFLAFLSYNDSEVNEY---KYTWMGDDIKYPAVMSQRYPKTGSRNPNVTVNVV 396
            ....:..:||||..||||..|||.|...   ::|    ...||......|||.|..||:|.:.||
  Rat   241 HSHIAHWWSPDGERLAFLMINDSLVPNMVIPRFT----GALYPKAKQYPYPKAGQANPSVKLYVV 301

  Fly   397 NLSVIKYIFPTQI--KLPSEL--SNGSYVGGLTWASSTDLSVTVTNREQTKATTVLCRAPHFHCQ 457
            ||     ..||..  .:|.::  |...|:..:.|.|:|...|...||.|..:...:|.:....|.
  Rat   302 NL-----YGPTHTLELMPPDIFKSREYYITMVKWVSNTRTVVRWLNRPQNISILTVCESTTGACS 361

  Fly   458 AVHTEVTINDGWV-LPSERPIFSVRNQGHNRLGKMVQNAEEIQAESQNVNVTDGQTHTTHEISNG 521
            ..: |:| :|.|: ..:|.|:||                                       .:|
  Rat   362 RKY-EMT-SDTWISKQNEEPVFS---------------------------------------RDG 385

  Fly   522 GYLLKRLPVRDGEHGHYRHV-VFISSLDRRPVP---LTMGRFEVTEIVGWDEPHEIVYFMAAPEK 582
            ......:||:.|..|.:.|: :|:.......:.   ||.|.:||..|:.:||..:.:||::. |.
  Rat   386 SKFFMTVPVKQGGRGEFHHIAMFLVQSKSEQITVRHLTSGNWEVIRILAYDETTQKIYFLST-EF 449

  Fly   583 RPGERHLYKISLKLNVTESNRTYITSTSPTCLTCDNTESTYRLHRARISQRGDRWEDIVARLEPD 647
            .|..|.||..|     ||.      ..|..|::|:                          ...:
  Rat   450 SPRGRQLYSAS-----TEG------LLSRDCISCN--------------------------FRKE 477

  Fly   648 DCLYDIPKNCLFNRVQFSQDYSYYVQECLGPEAPSVYLVETASNDKIYVLNAGDVLRHRL--SQL 710
            ||.|       |: ..||....:::..|.||:.|.|.|..|.:....|:|....:::..:  .:|
  Rat   478 DCTY-------FD-ASFSPMNQHFLLFCEGPKVPMVSLHSTDNPSNYYILERNSMMKETIQKKKL 534

  Fly   711 AIPQSRTFSVEIRHGFHAQVRLFLPPGMREEEDVAFPLVLHVDASPGSQLVTERFHVDWNWYLAS 775
            |..:.|...::   .:...::|..|....|:...|  |:|.:|..||.|:|||:|||||:..|..
  Rat   535 AKREIRILHID---DYELPLQLSFPKDFLEKNQYA--LLLIIDEEPGGQMVTEKFHVDWDSVLID 594

  Fly   776 QRSFIVAQIDGRGSGFQGELLRTQVHGKLGTVEVEDQLGVLTYLRDNLK--FIDPLRICAFGWGY 838
            ..:.|||:.|||||||||..:..::|.:.|:||.:||:..:.||   ||  :||..|:..||.||
  Rat   595 TDNVIVARFDGRGSGFQGLKVLQEIHRRTGSVEAKDQIAAIKYL---LKQPYIDSKRLSIFGKGY 656

  Fly   839 GGYASSMMLIDDSQQVLQCAVAINPIVNFGFHYSFFTERYIPLKGDYLRALQEADLTMKAGNIKG 903
            |||.:||:|..| ::..:|...:.||.:...:.|.|:|||:.:........|.:.:......:|.
  Rat   657 GGYIASMILKSD-EKFFKCGTVVAPISDMKLYASAFSERYLGMPSKEESTYQASSVLHNIHGLKE 720

  Fly   904 RNLMLMHGTADTLVHQEHTLMLVRALVEQQVKFRHQVYPDEDHAIA-RSLSHVYKTMEWYFDEC 966
            .||:::||||||.||.:|:..|::.|::..|.:..||||||.:.|: :|..|.|.|:..:|.:|
  Rat   721 ENLLIIHGTADTKVHFQHSAELIKHLIKAGVNYTLQVYPDEGYHISDKSKHHFYSTILRFFSDC 784

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45002	NP_728041.3	DPPIV_N	278..681	CDD:395744	105/414 (25%)
		Peptidase_S9	765..969	CDD:459761	79/205 (39%)
Dpp10	NP_001402045.1	DPPIV_N	137..504	CDD:395744	124/544 (23%)
		Peptidase_S9	584..786	CDD:459761	79/205 (39%)