Protein Alignment Ubr1 and PRT6

DIOPT Version :10

• Sequence 1: NP_573184.1
• Gene: Ubr1 / 32687
• FlyBaseID: FBgn0030809
• Length: 1824
• Species: Drosophila melanogaster
• Sequence 2: NP_195851.2
• Gene: PRT6 / 830916
• AraportID: AT5G02310
• Length: 2006
• Species: Arabidopsis thaliana
• Alignment Length: 2271
• Identity: 461/2271 - (20%)
• Similarity: 783/2271 - (34%)
• Gaps: 774/2271 - (34%)

  Fly     8 DVVVAPPAECSSPLKEWRLKRQAGTLDRSDIIEFLKRESPKYFDYQTSATVKDTNV--------- 63
            |:|:...|....| |::|.||        .::||::....|..:..::....|.:|
plant    17 DLVIERLASVGVP-KKYRSKR--------GLVEFVRANPAKISELVSALLPTDDDVKLGLKEARE 72

  Fly    64 --------ITLKCMFKESLAKEEIIDVVVEFMLGDNPSSALEKL-RLEGNTATVCGKVFKNGEPT 119
                    .|:|..|:||:      :::...|..|.|..:|..| :|..:...|||.|:...:..
plant    73 RPRKSAVSPTMKKRFRESM------NMLQWLMFQDEPDVSLRNLAKLNLDQRGVCGSVWGQNDIA 131

  Fly   120 YSCRECGVDPTCVLCVNCFKRSAHRFHKYKMSTSGGGGCCDCGDDEAWKKDQYCELHLANRK-NP 183
            |.||.|..||||.:||.||:...|..|.|.:..: |||||||||:.|||.|.:|..|..:.: .|
plant   132 YRCRTCENDPTCAICVPCFQNGDHNSHDYSIIYT-GGGCCDCGDETAWKPDGFCSNHKGSEQIRP 195

  Fly   184 LESKILTDAVLERVEICFGAILAFCVSYLEIEPNASLQCLDGNVEGGQVDGAQYCTVLYNDESHT 248
            | |:.|.::|        |.||           :|...|.:..:...:..|.:
plant   196 L-SENLANSV--------GPIL-----------DALFTCWNNKLLSAESSGQK------------ 228

  Fly   249 FDQVIQTLTKIAKCRAKDAMEIVAAIDREGRAVVKCDTFEECNKLKVSIENQMILPTSLVSTARN 313
                        ..|:.|.:.|:.                     |:|.|...|:...|:..:.:
plant   229 ------------GARSNDTLVILQ---------------------KMSNELTFIVVEMLLEFSMS 260

  Fly   314 NQSLRTSVLHIGAVACQQFALQLLGWFQEFLVRHYLFRKTFSE----LVQRKQETFCIRHILEYD 374
            ::||.:                            ::.|:..|.    .:..|.|.|     |:.|
plant   261 SESLLS----------------------------FVSRRIISSSGLLSILLKAERF-----LDQD 292

  Fly   375 V--KLWKTARTCWHRLLISGMLMEYDNKMILAQEFSRRYATIVEDFISDDHDHAFS----IVSLS 433
            |  ||        |.|.:. ::.:...|...|:.|...|..::.:.:....|:||.    :.:.|
plant   293 VMKKL--------HDLFLK-LIGDPVFKCEFAKAFVSYYPVVISEVVKQGTDNAFKKYPLLSTFS 348

  Fly   434 VQLFTVPSIAHHLIAHEGIFDKLLHTFYHVAIEKFIRNKTLHFSKNIASLTFFKRANYILYDLRY 498
            ||:.|||::...|:....:...||.....:.:.....:..|..:| :..|.  :.:..::.||::
plant   349 VQILTVPTLTPFLVKEMNLLAMLLGCLSDIFVSCSGEDGLLQATK-LERLC--ETSERVIGDLKF 410

  Fly   499 LLSLKPDVLSNDLRNGFLEGCRALMRVLNVMQGMESMTRQTGQHMDYEPEWECAFNLHIKLATTI 563
            ::|  ..::|....:...|..|:.:.:|...|||..:.|:||..:|.|.::   .:|...|..:|
plant   411 VMS--HAIVSKYATHEHRELSRSWLTLLTFAQGMNPLKRETGIPIDEENDY---MHLFFVLGHSI 470

  Fly   564 SQV--------------------------IDWASGDVKLLRKLYKMT-----MRALVSNS----- 592
            :.:                          .|...||.:...|:.:::     ..|:||:|
plant   471 AVIHSLLVNGTYSAASDEEIENDRNAKEEFDKCDGDGERYAKVGRLSHEDSVCTAIVSSSSFDSS 535

  Fly   593 ------------------------------------------FI--------------------- 594
                                                      |:
plant   536 MASEVHKIDPFHALLPSSAIYLIRECLKVLETCLGNDEGISKFLCKLSSSSGRNIPESKMSWPRR 600

  Fly   595 ------VGG------------------------------EKVMQP------------KKV----A 607
                  .||                              :.|..|            |:|    |
plant   601 DLLNVETGGSVSSNLASSSRDPSTGLSPLCGDIQTNLSLDNVCGPYGVVQTDVTADSKRVSCNSA 665

  Fly   608 DHVANC-------------LVYDISVQPVSIHLPLSRFFA-----GIYLHLGAHDLTYDGLQTET 654
            |...|.             :.||:|.|.:|:||||.|..:     .:.:..| ...:|:|:....
plant   666 DLTKNASGLRILGLCDWPDIHYDVSSQAISVHLPLHRLLSLLIQKALRICYG-ESASYNGVSISH 729

  Fly   655 E--------------------ALSIKLTPREIIEPVLCTQAMIAQVGAGLWRRNGYTLLHQLYFY 699
            |                    ||        ::|.||..:...|||.||:|::||.:.|....:|
plant   730 EIPHADFFSSVIGDFHPCGFSAL--------VMEHVLQIRVFCAQVIAGMWKKNGDSALVSCEWY 786

  Fly   700 RNVRCRVEMLDRDIACLQIGASLMESNEFLIHVLNRFNTIPWLQENYWSLLSGNEMNDDIIREAS 764
            |:||...:.|:.|:..||..|:|..::.::..:|:||....:|           .:|.||..|..
plant   787 RSVRWSEQGLELDLFLLQCCAALAPADSYVDKLLSRFGLSSYL-----------SLNPDITNEYE 840

  Fly   765 --IFDEFLELLIVIIGERWMPGVSMVTEEDRLRKEIIQLLCIKPYSHSELSRALPDGNSGNSDNV 827
              :..|.|.|||.|:.||...|:|..   :.||:|||..|....::||:|.::||...| .||.:
plant   841 PVLVQEMLGLLIQILQERRFCGLSTA---ESLRREIIFKLATGDFTHSQLVKSLPRDLS-KSDEL 901

  Fly   828 FEEVINTVAVFKKPVGADSKGVYELKEHLLKEFNMYFYHYTKEDKSKAEELQRERRKAKKQLVCC 892
             :||::.|:|:..|.|. ::|.|.|:....||.::|...:...|...|||  |..|......:..
plant   902 -QEVLDDVSVYCNPSGM-NQGKYSLQSSCWKELDLYHPRWQSRDLQSAEE--RFSRYCGVSALTT 962

  Fly   893 PPPMLPKLTPAFTPMANILQCPVFLNICSLIMERAL----NAYSRSFTESHLQKVLHLLGYAI-- 951
            ..|....:.|....:|.|..|.....|.|..:..||    :..||: .:..|...|.||..::
plant   963 QLPRWRMIYPPLKGLARIGTCKATFQIISSALYYALQSGTSVKSRA-PDGVLITALQLLSLSLDI 1026

  Fly   952 ---QEE-------LSEHYPFL--------SFYERSQEYGILEKLEELARCPRLEAHYDF------ 992
               |.:       |....|.|        ...:.:::..:|..|..|.:....:..:.|
plant  1027 CTQQRQSNSQDCCLENSIPILELAGLEIIGIAQGTEKESLLSLLVSLMKTRMGDGRHQFPEPGSC 1091

  Fly   993 --VLWTIERFKQLQAKQAPS----DGRAGPSCSQQGTGGKLSLSAEEQAREERENRARLAAERRA 1051
              ..|.....|:..|..:..    ...|.....|.|....:|.|..::.|:.:      |.||:|
plant  1092 NISSWIGNLLKKFSAIDSVCMNLLQSLAPEVVGQSGFDKVMSGSTSDEKRKAK------AKERQA 1150

  Fly  1052 HIMAQMQKAQKSFIS-----------------SNAEMFADTENETR-----------KESAS--- 1085
            .|||:|:..|..|:|                 |::.|..|:|...|           |:..|
plant  1151 AIMAKMKAEQSKFLSTLSSSMDDDDPRSEFETSDSVMEHDSEIAVREVCSLCHDPDSKDPVSFLI 1215

  Fly  1086 ------------TGPMDWEDIPPEEE------------------------------------QGA 1102
                        .||..|:..|..|:                                    :.|
plant  1216 FLQKSKLLSFVDRGPPSWDQCPQSEKKISVDGAPDLLRMNASSDSLRISSPLMLQLSDDTISESA 1280

  Fly  1103 VALES-KVACLGPDRKFYHGTDDTFKC--------ILCF-------------------------E 1133
            ..:|| |...:|..:.....:|...|.        |..:                         |
plant  1281 NMIESIKARLIGNGQTEKRSSDGRGKDESNMESLEIAMYQTVRNKIENMINQSLTRVDHQPHEAE 1345

  Fly  1134 NCA--ISRGGRQLVSSAFVQTSRVIFTTPNLRNSQSA-----------------LHISCCGHVMH 1179
            ||:  .|.||...:...|          |::|:.|::                 :::|.|||.:|
plant  1346 NCSEKNSVGGPSTLQGRF----------PDIRSRQTSRRPDAGSDGFHPIDCDGVYLSSCGHAVH 1400

  Fly  1180 YSCWLEYFTNEEFKELRRPHRNRAALAQAANVEFQCPYCRTLSNAIIPVTETLPAFSAPPSPNES 1244
            .||...|..:.:.:..||.....|.:......||.||.||.|:|:::           |..|.:
plant  1401 QSCLERYLKSLKERSGRRTVFEGAHIVDLKKKEFLCPVCRRLANSVL-----------PECPGD- 1453

  Fly  1245 YLPLDSFVEIMSTLAIELGNVKDHELTTL-------PSVSNILRLSGVVGGLAQFERSVQLIKNP 1302
                          ...:..::|...|.|       ||    |.||   ..|.....:.::|::.
plant  1454 --------------LCSVSKLQDSPRTKLRRKDALQPS----LWLS---EALCLLRSAAEVIEDG 1497

  Fly  1303 PRLHADYIEGIEFLKKALLNTMKIQQSHLKDHP---AIESIEMVP---ILWDSCSYTLQALEI-- 1359
            .|......:|....:|.|.:..|:........|   .::.:.:.|   ::||:..|:|.::||
plant  1498 DRGKTVTPQGDGPRRKDLKSVSKMLWDFYFPKPEDKTLKRLWLPPQSIVMWDTLKYSLISMEIGT 1562

  Fly  1360 --------YLYAVE---KPLKAE--------LSMRHQSCARNLVRACSRSSALEW--ETDLPLLP 1403
                    .:|.::   :.||..        |.:...|..:|.:....|...::.  |:....:.
plant  1563 RFAKNSMLPVYCIDSLYEELKTSKGTILSVLLRVVQSSRTKNTIHVRQRFVGMKHLAESICYGVS 1627

  Fly  1404 PMRSQAEFSS-------RLLDTIFNQNDTSVLEWDCFRVL------VPFQFGVLNLMVPEKGYKT 1455
            ...|.:.|.|       :.:|.::|:....||..|.|..|      :||.|     :..|:...:
plant  1628 SSSSSSIFGSEGTTGSLKNIDLLWNRASDPVLAHDPFSSLMWALFCLPFPF-----LTCEESLLS 1687

  Fly  1456 IIPSGSMFDFYIMQTMFLAQLTKAVLCFDVEKEKAKRAEKAPNSELTQLDYIEQLPSRIRDNM-- 1518
            ::        :|..::.|.| |....|       |.|.     |||::|::.|.|.:.|.:.:
plant  1688 LV--------HIFHSVSLVQ-TVIAYC-------ACRP-----SELSELNFGENLLNDISNALRE 1731

  Fly  1519 ---IDFYRRYNIPARVLQKTKQKQLVEEESEENQGHGQTVVIPCESHHLALLLEYVQRQMSSFLR 1580
               .:::|..|:.                            :.|:      :.:.:::....|||
plant  1732 SGGWEYFRSNNMD----------------------------LSCD------IKDTIRKYSLPFLR 1762

  Fly  1581 CSCLFYRFLTDVDFPDTFPT---DQPDRFDLMCQYLGLDPMLGVYFDMETVYATM--------MH 1634
            ...|.::.|...      |.   ::.|.|||..     ||...   :|:.:|:..        :.
plant  1763 RCALLWKLLKST------PRKLHEESDMFDLPS-----DPTTD---NMDFIYSPQSELNHVQELE 1813

  Fly  1635 SFASHPHIDREVE------------QRCQPDAR-----RSLQVEPC----LRPLPRLKVLCDDFS 1678
            ...:.|.||..:.            |..|.:.|     |||.:.|.    |..||.|      :.
plant  1814 KMFNIPPIDIILNDELLRSSTQIWLQHFQREYRVNRVKRSLCITPVVPFQLMKLPNL------YQ 1872

  Fly  1679 DLINSVSDIFCPNNEREEMKTPTMCLICGLILCGQ--SYCCQPELGKVSVGACTHHAHACGAEVG 1741
            ||:.......|.|..: .::.|.:||:|| .||..  |.||: |.|      |.:||..|||..|
plant  1873 DLLQRCIKKRCVNCTK-VIEEPVLCLLCG-SLCSPIWSPCCR-ESG------CPNHAITCGAGTG 1928

  Fly  1742 IFLRIRDCQVVYLGRGKGCFVPPPYLDEYGETDMGLRRGNPLRLSQAAYRKIYLQWLGHGL 1802
            :||.||...::.....:....|.||||.:||.|:.:.||..|.|::..|..:......|||
plant  1929 VFLLIRRTTILLQRFARQSPWPSPYLDTFGEEDIDMIRGKRLYLNEERYAALTYLVGSHGL 1989

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubr1	NP_573184.1	UBR-box_UBR1_like	108..176	CDD:439070	33/67 (49%)
		ClpS	236..301	CDD:460621	6/64 (9%)
		RING-H2_UBR1-like	1166..1227	CDD:438145	20/77 (26%)
		PRT6_C	1345..1799	CDD:465944	113/528 (21%)
PRT6	NP_195851.2	UBR-box_UBR3	119..188	CDD:439071	33/69 (48%)
		RING-H2_UBR1-like	1388..1448	CDD:438145	19/70 (27%)
		PRT6_C	1522..1984	CDD:465944	115/550 (21%)