Protein Alignment Ubr1 and ubr3

DIOPT Version :9

• Sequence 1: NP_001245723.1
• Gene: Ubr1 / 32687
• FlyBaseID: FBgn0030809
• Length: 1824
• Species: Drosophila melanogaster
• Sequence 2: XP_012826536.1
• Gene: ubr3 / 100498471
• XenbaseID: XB-GENE-1219144
• Length: 1866
• Species: Xenopus tropicalis
• Alignment Length: 2140
• Identity: 431/2140 - (20%)
• Similarity: 750/2140 - (35%)
• Gaps: 644/2140 - (30%)

  Fly     5 DMEDVVVAPPAECSSPLKEWRLKRQAGTLDR--------SDIIEFLKRESPKYFDYQTSATVKDT 61
            |.|.......::.|.|.:...|:|..|.|||        .:.:|:
 Frog    11 DKEATAALLKSKLSRPDQSPGLERLNGLLDRVLCVGGPAGEALEW-------------------- 55

  Fly    62 NVITLKCMFKESLAKEEIIDVVVEFMLGDNPSSALEKLRLEGNTATVCGKVFKNGEPTYSCRECG 126
                .||:.......|:....|..:   ||              ||:||.|:......|.||.||
 Frog    56 ----CKCLLAGGDKFEDFCQAVRSY---DN--------------ATLCGLVWTANFVAYRCRTCG 99

  Fly   127 VDPTCVLCVNCFKRSAHRFHKYKMSTSGGGGCCDCGDDEAWKKDQYCELHLANRKN-----PLES 186
            :.|...||..||.:..|..|.:.|..|..||.|||||....::..:|:.|.....:     |.:.
 Frog   100 ISPCMSLCAECFHQGEHAGHDFNMFRSQAGGACDCGDSNVMRESGFCKRHRVKLSSCVPSVPQDL 164

  Fly   187 KILTDAVLERVEICFGAILAFCVSYLE---IEPNA----------SLQCLDGNVEGGQVDGAQYC 238
            .::::.|:.|       .:.:.:.||.   .||.|          :||.||..:
 Frog   165 LVMSELVIPR-------FIFYLIQYLRDGYSEPGAEASPEKDLQKTLQMLDPQI----------- 211

  Fly   239 TVLYNDESHTFDQVIQTLTKIAKCRAKDAMEIVAAIDREGRAVVK----------CDTFEECNKL 293
                        ..::.|||:.     .||..|.......:.:.|          |....|  |.
 Frog   212 ------------SFLEDLTKMG-----GAMRSVLTQVLTNQQLYKDLSSGPGESTCSKSHE--KY 257

  Fly   294 KVSI-ENQMILPTSLVSTARNNQSLRTSVLHI----GAVACQ----------QFALQLLGWFQEF 343
            .::: |:.:.:|...||:....||..||.|.:    ||...|          |...|.:|..:..
 Frog   258 LIALKESGLSIPEENVSSGAQEQSPGTSTLAVKEVAGAEGAQGQLESSDEEDQDGRQCVGKRKRV 322

  Fly   344 LVRHYLFRKTFSELVQRKQETFC-IRHILEYDVKLWKTARTCWHRLLISGMLMEYDNKMILAQEF 407
            .:......::..::::.|    | :..:|.:.:|.....:..   ..:..||.:.|.|:...:.|
 Frog   323 KLSSNTKDQSIMDMLKHK----CFLEELLFWTIKYEFPQKMV---TFLLNMLPDQDYKIAFTKTF 380

  Fly   408 SRRYATIVEDFISDDHDHAFS--IVSLSVQLFTVPSIAHHLIAHEGIFDKLLHTFYHVAIEKFIR 470
            .:.||.|::...........|  ||.:|||||:...:|..:.....:.|.::....::.....|:
 Frog   381 VQHYAFIMKTLKKSHESDTMSNRIVHISVQLFSNEELARQVTEECQLLDIMVTVLLYMMESCLIK 445

  Fly   471 NK------TLHFSKNIASLTFFKRANY--ILYDLRYLLSLKPDVLSNDLRNGFLEGCRAL---MR 524
            ::      :||...|... ...|...|  ::.|...:||      ...:...|||....|   |.
 Frog   446 SELQDEENSLHVVVNCGE-ALLKNNTYWPLVSDFINILS------HQSVAKKFLEDHGLLVTWMN 503

  Fly   525 VLNVMQGMESMTRQTGQHMDYEPE-WECAFNLHIKLATTISQVIDWASGDVKLLRKLYKMTMRAL 588
            .::..|||....|:..:|:::|.: :..||...::...                     ..|..|
 Frog   504 FVSFFQGMNLNKRELTEHVEFESQTYYAAFAAELEACA---------------------QPMWGL 547

  Fly   589 VSNSFIVGGEKVMQPKKVADHVAN-CL------------VYDISVQPVSIHLPLSRFFAGIYLH- 639
            :|:.      ||...::...:|.. ||            |.:.:...|:.||||.|::| ::|.
 Frog   548 LSHC------KVPDTQEYTRNVVRYCLEALQDWFDAINFVDEPAPNQVTFHLPLHRYYA-MFLSK 605

  Fly   640 -LGAHDLTYDGLQTETEALSIKLTPREIIEPVLCTQAMIAQVGAGLWRRNGYTLLHQLYFYRNVR 703
             :...::..|.:..:.|.| :||    ::.|:| .||.::::.:.:|.|||..:..|...|....
 Frog   606 AIKCQEIDLDSILPDQEML-MKL----MVHPLL-IQASLSEIHSNMWVRNGLQIKGQAMTYVQSH 664

  Fly   704 CRVEMLDRDIACLQIGASLMESNEFLIHVLNRFNTIPWLQENYWSLLSGNEMND--DIIREASIF 766
            ....|:|.||..||:.||.::.:.|:..|..||..:..|      .::....|.  |...|.|:.
 Frog   665 FCNSMIDPDIYLLQVCASKLDPDYFISSVFERFKVVDLL------TMASQHQNTVLDADHERSML 723

  Fly   767 DEFLELLIVIIGERWMPGVSMVTEEDRLRKEIIQLLCIKPYSHSELSRALPDGNSGNSDNV---- 827
            :..|..|::::..|...|   :|:::.||.|:|..||:...:||.|...:|:..:..|..:
 Frog   724 EGALTFLVILLSLRLHLG---MTDDEILRAEMISQLCMNDRTHSSLLDLIPESPNPKSGIMPGSC 785

  Fly   828 -FEEVINTVAVFKKPV----GADSKGVYELKEHLL-KEFN--------MYFYHYTKEDKSKAEEL 878
             ||.|::.||.||.||    |:..:|:|..|..:. :||:        :|     :.|...|.:.
 Frog   786 SFESVLSAVADFKAPVFEPGGSMQQGMYTPKGDIWDQEFDPVMVILRTVY-----RRDVQSAMDR 845

  Fly   879 QRERRKAKKQLVCCPPPMLPKLTP---AFTPMANILQCP-----VFLNICSLIMERALNAYSRSF 935
            .....|...:....|.|...|.:|   ::..:..:|.|.     :|..:..::|:.      ::.
 Frog   846 YTAFLKQSGRFSGNPWPPYKKRSPLHHSYKGLMRLLHCKTLHIVLFTLLYKILMDH------QNM 904

  Fly   936 TESHLQKVLHLLGYAIQ-----EELSEHY------------------------------------ 959
            :|..|..||:|:...::     |...|::
 Frog   905 SEHVLCMVLYLIELGLENSPEDESCEENFAGPDRCHDSWFPGSNLLCNMRHFINYVRVRVPETAP 969

  Fly   960 -----------------------PFLSFYERS---QEYGIL----EKLEELARCPRLEAHY---- 990
                                   |.|...|.|   |.:.::    :|.:|:......||:.
 Frog   970 EVRREPPASTSTDGPSSAQNARRPSLLQRENSGTAQVFSLVAERRKKFQEIINRNNSEANQVVRP 1034

  Fly   991 --DFVLWT-----------------------IERFKQLQAKQAPSDGRA-----GPSCSQQ---- 1021
              ..:.||                       |:..|:|..||   |...     .|.|..|
 Frog  1035 KSSALKWTAPGATPQLTTVILEVKESMLSLLIKLHKKLSGKQ---DSYCPPWLDDPECLVQPDLP 1096

  Fly  1022 ----GTG----GKLSLSAEEQAR--------------------------------EERENRARLA 1046
                |.|    .::.|.|..|:|                                |||..:||
 Frog  1097 GYCHGDGVTAVERILLKAASQSRLNRQSIDEICKKAPPPVPPKKSSPADKKTLGKEERRQKAR-- 1159

  Fly  1047 AERRAHIMAQMQKAQKSFISSNAEMFADTENETRKESA-----------------STGPMDWEDI 1094
             ||:..::|:....||||:.:..:: ...|::...|.|                 .:|| ..||.
 Frog  1160 -ERQQKLLAEFASRQKSFMETAMDV-ESPESDVAMEIAGAEQHVAEPIYDCVICGQSGP-STEDR 1221

  Fly  1095 PPEEEQGAVALESKVACLGPDRK---------------FYHGT----DDT--------FKCILCF 1132
            |    .|.|.|....:.||..||               :..||    :|.        ||...|.
 Frog  1222 P----LGLVVLLQASSVLGHRRKSTEPKKLPTTEEEQIYQEGTCAAANDVKLAILQRYFKDSSCL 1282

  Fly  1133 ENCAIS-RGGRQLVSSAFVQTSRVIFTTPNLRNSQSALHISCCGHVMHYSC---WLEYFTNEEFK 1193
            ::.::. .||      .:|||                     |||.:|..|   ::|...|::
 Frog  1283 QSVSVGWEGG------VYVQT---------------------CGHTLHIDCHKSYMESLRNDQ-- 1318

  Fly  1194 ELRRPHRNRAALAQAANV---EFQCPYCRTLSNAIIPVTETLPAFSAPPSPNESYLPLDSFVEIM 1255
                       :.|..:|   ||.||.||..:|::      ||.|....:...|:....:..:.:
 Frog  1319 -----------VLQGFSVDKGEFTCPLCRQFANSV------LPCFPGDSTERGSWHSHAASSKSL 1366

  Fly  1256 STLAIELGNVKDHELTTLP-SVSNILRLSGVVGGLAQFERSVQLIKN-PPRLHADYIEGIEFLKK 1318
            ..|..|:.:::: :|.|.| |:|:...||      .:.|..::.||: ..:.:.||
 Frog  1367 QELIKEVEDLQE-QLGTFPVSISSETNLS------KEMEAVMKDIKSTTQKKYTDY--------- 1415

  Fly  1319 ALLNTMKIQQSHLKDHPAIESIEMVPILWDSCSYTLQALEIYLYAVEKPLKAELSMRHQSCARNL 1383
                 .|.|.|...|.                        :::|:|.: ...||.:.|  |..||
 Frog  1416 -----SKTQGSPDNDF------------------------LFMYSVAR-TNLELELIH--CGDNL 1448

  Fly  1384 ----VRACSRSSALEWETDLPLLPPMRSQAEFSSRLLDTIFN--QNDTSVLEW------DCFRVL 1436
                ..|..:.|.|.     .|...:.......|  :|..:|  :..|.|::.      |..|..
 Frog  1449 CSGGASAAGKRSCLN-----QLFHVLAMHMRLYS--IDPEYNPWKKLTQVIQKKPSLGDDEEREE 1506

  Fly  1437 VPFQF-GVLNLMVPEKGYKTIIPSGSMFDFY--IMQTMFLAQLTKAVLCFDVEKEKAKRAEKAPN 1498
            ||..| .|.:|::.:   ...:|.....:.:  |::.::....|:|:....|:.:...|.....:
 Frog  1507 VPILFRDVTSLLLIQ---VLTMPQPLCKEHFVCIVKVLYTLLYTQAITSLSVKLQAEDRKVWRES 1568

  Fly  1499 SELTQLDYIEQLPSRIRDNMIDFYRRYNIPARVLQKTKQKQLVEEESEENQGHGQTVVIPCESHH 1563
            ....:..|....|   .:.::.|         |:.:..:..|.::|..::.......     :.:
 Frog  1569 GSSKKSSYSSGKP---WEALLGF---------VISELSRGSLYQDEETDSINMSDFT-----AWY 1616

  Fly  1564 LALLLEYVQRQMSSFLRCSCLFYRFLTDVDFPDTFPTDQPDRFDLMCQYLGLDPMLGVYFDMETV 1628
            ...:..|:|:....|||.:......|..:|.|.   ..:.|.|.::...|||.|.
 Frog  1617 EDAIEHYLQQFCLPFLRITSFLQHHLFGLDLPS---CQEEDEFTVLSNCLGLLPS---------- 1668

  Fly  1629 YATMMHSFASHPHIDREV------EQRC---------QPDARRSLQVEPCLRPLPRLKVLCDDFS 1678
            ::...|.|.|...:|..|      .|.|         .||....|.::.....||||..|.:::
 Frog  1669 FSEASHQFVSASLLDWPVSAFDLISQWCSEVNLFSDKHPDQANVLLIQDTKWDLPRLLQLPENY- 1732

  Fly  1679 DLINSVSDIF---CPNNEREEMKTPTMCLICGLILCGQSYCCQPELGKVSVGACTHHAHACGAEV 1740
               |::...:   |.:...:..|.|.:||:||..:|.:..||:.:    |...|..|:..|||..
 Frog  1733 ---NTIFQYYHRKCCSVCTKVPKDPALCLVCGTFVCLKGLCCKQQ----SYCECVLHSQNCGAGT 1790

  Fly  1741 GIFLRIRDCQVVYLGRGKGCFVPPPYLDEYGETDMGLRRGNPLRLSQAAYRKIYLQWLGH 1800
            ||||.|....::.:...:.|.....|||.:||.|..||||.||.:.:..|..:..||:.|
 Frog  1791 GIFLLINASVIIIIRGHRFCLWGSVYLDAHGEEDRDLRRGKPLYICKERYSMLEQQWVSH 1850

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubr1	NP_001245723.1	zf-UBR	109..176	CDD:280386	25/66 (38%)
		ClpS	236..301	CDD:280736	11/75 (15%)
ubr3	XP_012826536.1	zf-UBR	81..149	CDD:366980	25/67 (37%)
		RING-H2_UBR3	1206..1344	CDD:319397	39/188 (21%)
		RING-H2 finger (C3H2C3-type)	1208..1335	CDD:319397	36/171 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D34639at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010