| Sequence 1: | NP_573183.2 | Gene: | RhoGAP15B / 32686 | FlyBaseID: | FBgn0030808 | Length: | 1552 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_476510.1 | Gene: | GIT2 / 9815 | HGNCID: | 4273 | Length: | 759 | Species: | Homo sapiens |
| Alignment Length: | 634 | Identity: | 125/634 - (19%) |
|---|---|---|---|
| Similarity: | 207/634 - (32%) | Gaps: | 183/634 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 163 GKADEDREGSRY----ASNASLDCSESSHSGKFKSQSPG-------YVDAVDSSIPQSDHPDPNG 216
Fly 217 HHPQAESSSA---------------EQSSGSQDGDDD---NNLLRSLGTTSKLLGEAIGERITFK 263
Fly 264 AKGAKKRLDR-----NFKSSTEAISN-------IGADAGRSLKHASKRFGSNFSLGRNKDKADIG 316
Fly 317 IGGRPGGSGEMDLDRRQTMPSTEVFNTIQFSSPLNRNGGLPD-LRENDAKLQ----KEDYLRPDP 376
Fly 377 DQEDDGCYEVPK-TQGKPPSYDEALRSRPSPSDSPMSRNLAQEAAQLVQLRNQRQLSSSSSNGDE 440
Fly 441 SPRLPMPAFPPPRLSQQPEQFRMDALQP-PVRQKRRKNYEHIELRRPPVDSAQLEELNRAAAAAE 504
Fly 505 REESLLISAKNAEAETKTPKPERSDSWEFYGEDENEEEDRDEEQEGSSSPEPLYANQEATYGKLF 569
Fly 570 EMATAGSSRSNV-----LTPNQVAEQQQLACITEDSELDACEGAVGGVP-LP--QAVIEEFDPLS 626
Fly 627 SKCSTLARSNKSNELLLLEHLLEEDTYGTVKAEQDDVSMCTSEEEPTTSAATSPKPQQPQIVHQN 691
Fly 692 ARLLSDSMENMLDSDQERAKPYLSRMPESANKASGPV-----DLASASR 735 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| RhoGAP15B | NP_573183.2 | RhoGAP_ARAP | 1095..1277 | CDD:239850 | |
| GIT2 | NP_476510.1 | ArfGap | 2..124 | CDD:214518 | |
| ANK | 109..220 | CDD:238125 | |||
| ANK 1 | 132..161 | ||||
| Ank_2 | 137..229 | CDD:289560 | |||
| ANK repeat | 137..165 | CDD:293786 | |||
| ANK 2 | 166..195 | ||||
| ANK repeat | 167..197 | CDD:293786 | |||
| ANK 3 | 199..228 | ||||
| GIT_SHD | 266..294 | CDD:285690 | 7/31 (23%) | ||
| GIT_SHD | 330..358 | CDD:285690 | 4/27 (15%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 379..422 | 8/44 (18%) | |||
| GIT_CC | 414..478 | CDD:293167 | 16/78 (21%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 480..538 | 16/82 (20%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 554..643 | 26/138 (19%) | |||
| GIT1_C | 638..752 | CDD:289013 | 28/128 (22%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5347 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||