| Sequence 1: | NP_573183.2 | Gene: | RhoGAP15B / 32686 | FlyBaseID: | FBgn0030808 | Length: | 1552 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_055531.1 | Gene: | ACAP1 / 9744 | HGNCID: | 16467 | Length: | 740 | Species: | Homo sapiens |
| Alignment Length: | 400 | Identity: | 79/400 - (19%) |
|---|---|---|---|
| Similarity: | 120/400 - (30%) | Gaps: | 132/400 - (33%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 114 EDSYPDP----DDEVPLRILRAAPQIPPKPLNILLDQRSSICSEVSTTSVQTPGKADEDREGSRY 174
Fly 175 A-----------SNASLDCSE------SSH-----------SGKFKSQSPGYVDAVDSSIPQSDH 211
Fly 212 PDPNG-----HHPQAESSSAE-------QSSGSQDGDDDNNLLRSLG-----TTSKLLGEAIGER 259
Fly 260 ITFKAKGAKKRLDRNFKSSTE--AISNIGADAGRS-------LKHASKRFGSNFSLGRNKDKADI 315
Fly 316 GIGGRPGGSGEMDLDRRQTMPSTEVFNTIQFSSPLNRNGGLPDLRENDAKLQKEDYLRPDPDQED 380
Fly 381 DGCYE----VPKTQGKPPSYDEALRSRPSPSDSPMSRNLAQEAAQLVQ-------------LRNQ 428
Fly 429 RQLSSSSSNG 438 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| RhoGAP15B | NP_573183.2 | RhoGAP_ARAP | 1095..1277 | CDD:239850 | |
| ACAP1 | NP_055531.1 | Required for formation of endosomal tubules when overexpressed with PIP5K1C | 1..382 | 21/94 (22%) | |
| BAR | 18..217 | CDD:299863 | |||
| PH | 266..360 | CDD:278594 | 15/72 (21%) | ||
| PH_ACAP | 268..364 | CDD:270070 | 15/76 (20%) | ||
| Required for interaction with GULP1 | 405..740 | 52/281 (19%) | |||
| ArfGap | 406..519 | CDD:279720 | 23/124 (19%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 525..581 | 17/79 (22%) | |||
| Prevents interaction with ITGB1 when S-554 is not phosphorylated | 525..566 | 15/64 (23%) | |||
| ANK | <592..692 | CDD:238125 | 7/48 (15%) | ||
| ANK repeat | 606..637 | CDD:293786 | 5/30 (17%) | ||
| Ank_5 | 626..680 | CDD:290568 | 3/14 (21%) | ||
| ANK repeat | 639..670 | CDD:293786 | 0/1 (0%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5347 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||