Protein Alignment RhoGAP15B and AGE1

DIOPT Version :9

• Sequence 1: NP_573183.2
• Gene: RhoGAP15B / 32686
• FlyBaseID: FBgn0030808
• Length: 1552
• Species: Drosophila melanogaster
• Sequence 2: NP_010812.3
• Gene: AGE1 / 852136
• SGDID: S000002932
• Length: 482
• Species: Saccharomyces cerevisiae
• Alignment Length: 354
• Identity: 76/354 - (21%)
• Similarity: 130/354 - (36%)
• Gaps: 102/354 - (28%)

  Fly   938 NPNLLMTSSS---SGNVKQQRVSHLYGVGKESERGVWMQKILESLTNS-----LPVK------YT 988
            :|.|..|..|   ||:  |.:.:|.:.:..::      ..|..|.:||     :|.|      :|
Yeast   100 SPQLSFTYLSTRLSGS--QHKSTHSHHINHQT------HPIHSSSSNSNSNNRIPTKTDSSKQHT 156

  Fly   989 CHYYRAGWCYLKNSITSEWSGTWLVLRKSQRRLIFVSEANGNVEKMDLRKARCIVLKESDESIDN 1053
            .|:..|      |:..|.......::||              ::|.:|:...|    .|..:::.
Yeast   157 QHFSFA------NAGASNRDELLSIVRK--------------IDKSNLKCCDC----GSTATVEW 197

  Fly  1054 LHVESGPMLMIDCPPYAVYMIMSSARETKIWRHI--IREVAHNNGFSLGDQQLTRYDVPVIVDKC 1116
            :.:....:|.|.|          |.....:..||  ||.:..:|..||....|.:.:|.   :..
Yeast   198 VSINLLCILCIKC----------SGVHRSLGSHISKIRSLTLDNFTSLELMHLLQNNVS---NSN 249

  Fly  1117 INFVYIHGSMSEGIYR----KSGSENSMHKLMSAFRADAFNVE---ITRNEYNEHDVANVLKRFM 1174
            :|.:|      |...|    |..:.||.....|.|..|.:..:   |..|:..|..:.:::|...
Yeast   250 VNAIY------ESNLRNFPVKKITANSDDSERSKFIIDKYQFKKFVIDSNQGREASLKSLIKAIH 308

  Fly  1175 RDLPERLLGKLTDSFVFVTELAVASEKIPIYRELLA--------RLSAIERETLR--RIVG--HL 1227
            .|            .||:.:.|:|..|..: |||.|        ..|:|.:.:|:  .||.  .:
Yeast   309 LD------------SVFMMQRAIAQSKYSL-RELTASEKEQNDLNHSSIFQYSLKHYEIVDGTPI 360

  Fly  1228 VFISSQQAKNKMSVQNLTMI---WGPTLL 1253
            .||:.....|.:.:.||..|   |.|.:|
Yeast   361 FFITEFLLCNGIHIDNLPKITTNWSPKVL 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP15B	NP_573183.2	RhoGAP_ARAP	1095..1277	CDD:239850	43/181 (24%)
AGE1	NP_010812.3	COG5347	164..480	CDD:227651	58/276 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900