DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoGAP15B and Smap1

DIOPT Version :9

Sequence 1:	NP_573183.2	Gene:	RhoGAP15B / 32686	FlyBaseID:	FBgn0030808	Length:	1552	Species:	Drosophila melanogaster
Sequence 2:	XP_003750716.3	Gene:	Smap1 / 684800	RGDID:	1585595	Length:	467	Species:	Rattus norvegicus

Alignment Length:	308	Identity:	65/308 - (21%)
Similarity:	114/308 - (37%)	Gaps:	70/308 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   413 RNLAQEAAQLVQLR----NQRQLSSSSSNGDESPRLPMPA-----FPPPRLSQQPEQFRMDALQP 468
            |||....:::..:.    ...|:......|:...||...|     |..|:..|..|.|..|
  Rat    61 RNLGVHISRVKSVNLDQWTPEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIRD---- 121

  Fly   469 PVRQKRRKNYEHIELR-----------RPPVDSAQLEELNRAAAAAEREESLLISAKNAEAETKT 522
              :.:::|.|:...:.           :|.|.|..|      .||.::.:......|..|.:.:.
  Rat   122 --KYEKKKYYDKNAIAITNISSSDAPLQPLVSSPSL------PAAVDKNKIEKEKEKKKEEKKRE 178

  Fly   523 PKPERSDSWEFYGEDENEEEDRDEEQEGSSSPEPLYANQEATYGKLFEMATAGSSRSNVLTPNQV 587
            .:||: .:.....|...::||:..|.:.|:||:.:   .|.|...|   ...|.:.:.|...|..
  Rat   179 KEPEK-PAKALTTEKLQKKEDQQPEPKKSTSPKNV---AEPTVDLL---GLDGPAEAPVTNGNTT 236

  Fly   588 AEQQQLACITEDSELDACEGAVGGVPLPQAVIEEFD-----PLSSKCSTLA---------RSNKS 638
            |...    :::|.::   .|.:...|||.||:.:..     |.::..||:.         ::.||
  Rat   237 AAPP----LSDDLDI---FGPMISNPLPAAVMPQAQGTASIPAAAALSTITSGDLDLFTEQTTKS 294

  Fly   639 NELLLLEHLLEEDT----YGTVKAEQDDVSMCTSEEEPTTSAATSPKP 682
            .|  ..:..|.:|:    ||| .|:|....:...   ||....||..|
  Rat   295 EE--GAKKQLSKDSILSLYGT-GAQQSTPGVFMG---PTNIPFTSQAP 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP15B	NP_573183.2	RhoGAP_ARAP	1095..1277	CDD:239850
Smap1	XP_003750716.3	ArfGap	20..120	CDD:279720	13/58 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900