Protein Alignment RhoGAP15B and Arfgap3

DIOPT Version :9

• Sequence 1: NP_573183.2
• Gene: RhoGAP15B / 32686
• FlyBaseID: FBgn0030808
• Length: 1552
• Species: Drosophila melanogaster
• Sequence 2: NP_001344685.1
• Gene: Arfgap3 / 66251
• MGIID: 1913501
• Length: 525
• Species: Mus musculus
• Alignment Length: 489
• Identity: 95/489 - (19%)
• Similarity: 149/489 - (30%)
• Gaps: 184/489 - (37%)

  Fly   447 PAFPPPR------------------LSQQPEQFRMDALQPP-----VRQKRRKNYEHIELRRPPV 488
            |..|||:                  .|.|||    .|...|     ..:|....         |.
Mouse   141 PVSPPPKEEDFFASHASLEVSGAMQASAQPE----SASSTPWGLETTPEKHEGG---------PG 192

  Fly   489 DSAQLEELNRAAAAAEREESLLISAKNAEAE---------------TKTPKPERSDSWEFYGEDE 538
            ....:|.||....||..|.|.:|..|..:|:               |.|...|.        |.:
Mouse   193 QGPSVEGLNTPGKAAPAEVSSIIKKKPNQAKKGLGAKKGSLGAQKLTNTSFTEI--------EKQ 249

  Fly   539 NEEEDRDEEQE----GSSSPEPLYANQEATYGKLFEMATAGSSRSNVLTPNQVAEQQQLACITED 599
            .:..|:.:|||    |:...|.:.::....| |..|::.....|.| |:..:..|.::|.
Mouse   250 AQAVDKRKEQEDLARGAPKEESIVSSLRLAY-KDLEISRKKDERLN-LSGQKKVEAERLG----- 307

  Fly   600 SELDACEGAVGGVPLPQAVIEEFDPLSSKCSTLARSNKSNELLLLEHLLEEDTYGTVKAEQDDVS 664
            ....:|...:.     .:|..:...:..:..|||:..:.
Mouse   308 MGFGSCRSGIS-----HSVTSDMQTIEQESPTLAKPRRK-------------------------- 341

  Fly   665 MCTSEEEPTTSAATSPKPQQPQIVHQNARLLSDSME---NMLDSDQERAKPY----LSRMPESAN 722
               .:|:|..|..:|......|   .::|...|.||   :...|..:.|..|    .||.||.|.
Mouse   342 ---YQEDPEDSYFSSSSKWSEQ---SSSRYFDDPMELRSSSFSSWDDGADSYWKKDSSRDPEPAM 400

  Fly   723 KASGPVDLASASRNRTNWFVPDKASCSDVTPNTSKTTPPIEGDSPPTYLEAIGGSKDAAGNQENR 787
            :::|..|..||.|.                               |.| |.||.:.:|.....|.
Mouse   401 RSTGSSDRPSARRK-------------------------------PEY-EPIGSTDEAQKKFGNV 433

  Fly   788 STIGS--------------RFR----QTINAISNVKLKMDAMKRKASFRGANQRQSDVRVALQMV 834
            ..|.|              |.|    .|.::||:..|..:..|:.|    .|...|:|      :
Mouse   434 KAISSDMYFGIQAQTDFETRARLERLSTSSSISSADLFDEQRKQTA----GNYNLSNV------L 488

  Fly   835 PRPSLSPLLIRYE-------GPLVRFPSGVVEDI 861
            |.   :|.:.:::       |.|..|.:||:..|
Mouse   489 PN---APDMAQFKQGVRSVAGKLSVFANGVMTSI 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP15B	NP_573183.2	RhoGAP_ARAP	1095..1277	CDD:239850
Arfgap3	NP_001344685.1	ArfGap	13..116	CDD:214518
		CDC27	<134..>292	CDD:312868	35/172 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..206		11/56 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..271		5/21 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900