DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment RhoGAP15B and Adap2

DIOPT Version :9

Sequence 1:NP_573183.2 Gene:RhoGAP15B / 32686 FlyBaseID:FBgn0030808 Length:1552 Species:Drosophila melanogaster
Sequence 2:XP_038942641.1 Gene:Adap2 / 56826 RGDID:708487 Length:400 Species:Rattus norvegicus


Alignment Length:458 Identity:86/458 - (18%)
Similarity:148/458 - (32%) Gaps:146/458 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   706 DQERAKPYLSRMPESANKASG------------PVDLASASRNRTNWFV-----PDKAS------ 747
            |:||.|..|..:.::|...:|            |..|..:..:.....:     ||.||      
  Rat     3 DRERNKKRLLELLQAAGTGNGHCADCGAAGPACPCTLVQSLSSSAEILLFHPADPDWASYKLGVF 67

  Fly   748 ----CSDV---TPNTSKTTP---PIEGDSPPTYLEAIGGSKDAAGNQENRSTIGSRFRQTINAIS 802
                ||.|   .|:.||...   ....||...::           ......::.::|...:....
  Rat    68 ICLHCSGVHRNFPDISKVKSVRLDFWDDSMVEFM-----------THNGNLSVKAKFEARVPTFY 121

  Fly   803 NVKLKMDAMKRKASF-RGANQRQSDVRVALQMVPRPSLSPLLIRYEGPLVRFPSGVVEDILKEMQ 866
            .|....|.:..|..: |...:||       :.:...::||...| ||.|  :..|  .|..:.::
  Rat   122 YVPQASDCLVLKEQWIRAKYERQ-------EFMAEKAVSPPGDR-EGFL--WKRG--RDNSQFLR 174

  Fly   867 NRKAIL-RERQFQTFLDQEMKTPREMIPLDTITTLQCVSNSRVTDTATHFYCFEITTSQPKNGNG 930
            .|..:| ||...:.:..:|.|||:.:|.:..:..                     |....|.|:.
  Rat   175 RRFVLLSREGLLKYYTKEEGKTPKAIINIKDLNA---------------------TFQTEKIGHP 218

  Fly   931 AGDAMSSNPNLLMTSSSSGNVKQQRVSHLYGVGKE---------SERGVWMQKILESLTNS--LP 984
            .|        |.:|....|..:...|.|  ..|||         :.|..:::.....|..|  :|
  Rat   219 HG--------LQITYRKEGQTRNLFVYH--DSGKEIVDWFNALRAARLQYLKLAFPDLPESELVP 273

  Fly   985 VKYTCHYYRAGWCYLKNSITSE-WSGTWLVLRKSQRRLIFVSE---------------------- 1026
            : .|.:|.:.|:.........| :...|..|...:|||::...                      
  Rat   274 L-ITRNYLKQGFMEKTGPKHREPFKKRWFALDPQERRLLYYKNPLDAFEQGQVFLGSNEQGYEVW 337

  Fly  1027 ------ANGNVEKMDL------RK--ARCIVLKESDESIDNLH-VESGPMLMIDCPPYAVYMIMS 1076
                  ..||..|:.|      ||  ..|...||..|.:::|. |.|.|:       ..::::.:
  Rat   338 EGLPQGIRGNRWKVGLTVITPERKFVFTCPTEKEQREWLESLRGVLSSPL-------SPLHLLTT 395

  Fly  1077 SAR 1079
            ||:
  Rat   396 SAK 398

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RhoGAP15BNP_573183.2 RhoGAP_ARAP 1095..1277 CDD:239850
Adap2XP_038942641.1 ArfGap 4..141 CDD:355783 25/147 (17%)
PH1_ADAP 156..264 CDD:270072 28/143 (20%)
PH2_ADAP 278..385 CDD:241282 20/106 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5347
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.